Phagocytosis Quiz
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Questions and Answers

Which of the following is the primary process by which neutrophils and macrophages destroy ingested microbes?

  • Pinocytosis
  • Phagocytosis (correct)
  • Endocytosis
  • Exocytosis

Which of the following are the principal phagocytic receptors on phagocytes?

  • Mannose receptors and other lectins
  • Receptors for antibodies and complement
  • Both A and B (correct)
  • None of the above

What is the process by which phagocyte oxidase converts molecular oxygen into superoxide anion and free radicals?

  • Phagolysosomal fusion
  • Respiratory burst (correct)
  • Oxidative burst
  • Phagocytosis

Which enzyme is responsible for converting arginine to nitric oxide in macrophages?

<p>Inducible nitric oxide synthase (iNOS) (D)</p> Signup and view all the answers

What is the cause of chronic granulomatous disease (CGD)?

<p>Inherited deficiency of phagocyte oxidase enzyme (A)</p> Signup and view all the answers

What is the purpose of neutrophil extracellular traps (NETs)?

<p>To trap and kill bacteria and fungi (A)</p> Signup and view all the answers

What is the reason why inflammation may cause tissue injury?

<p>The injury caused by enzymes and ROS liberated into the extracellular space (B)</p> Signup and view all the answers

What is the size range of particles that can be ingested through phagocytosis?

<p>Between 0.5 μm and 1 μm in diameter (B)</p> Signup and view all the answers

What are the two types of receptors that can bind to microbes during phagocytosis?

<p>Antibody receptors and complement receptors (B)</p> Signup and view all the answers

What is the purpose of the oxidative burst during phagocytosis?

<p>To convert molecular oxygen into superoxide anion and free radicals (B)</p> Signup and view all the answers

What is the main function of lysosomal proteases in phagocytes?

<p>Break down microbial proteins (C)</p> Signup and view all the answers

What happens to neutrophils in response to pathogens and inflammatory mediators?

<p>They die and extrude their nuclear contents to form NETs (A)</p> Signup and view all the answers

What is the cause of chronic granulomatous disease (CGD)?

<p>Inherited deficiency of the phagocyte oxidase enzyme (A)</p> Signup and view all the answers

What is the potential downside of releasing enzymes and ROS into the extracellular space to kill microbes?

<p>They may injure host tissues (D)</p> Signup and view all the answers

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