Podcast
Questions and Answers
Which of the following is the primary process by which neutrophils and macrophages destroy ingested microbes?
Which of the following is the primary process by which neutrophils and macrophages destroy ingested microbes?
- Pinocytosis
- Phagocytosis (correct)
- Endocytosis
- Exocytosis
Which of the following are the principal phagocytic receptors on phagocytes?
Which of the following are the principal phagocytic receptors on phagocytes?
- Mannose receptors and other lectins
- Receptors for antibodies and complement
- Both A and B (correct)
- None of the above
What is the process by which phagocyte oxidase converts molecular oxygen into superoxide anion and free radicals?
What is the process by which phagocyte oxidase converts molecular oxygen into superoxide anion and free radicals?
- Phagolysosomal fusion
- Respiratory burst (correct)
- Oxidative burst
- Phagocytosis
Which enzyme is responsible for converting arginine to nitric oxide in macrophages?
Which enzyme is responsible for converting arginine to nitric oxide in macrophages?
What is the cause of chronic granulomatous disease (CGD)?
What is the cause of chronic granulomatous disease (CGD)?
What is the purpose of neutrophil extracellular traps (NETs)?
What is the purpose of neutrophil extracellular traps (NETs)?
What is the reason why inflammation may cause tissue injury?
What is the reason why inflammation may cause tissue injury?
What is the size range of particles that can be ingested through phagocytosis?
What is the size range of particles that can be ingested through phagocytosis?
What are the two types of receptors that can bind to microbes during phagocytosis?
What are the two types of receptors that can bind to microbes during phagocytosis?
What is the purpose of the oxidative burst during phagocytosis?
What is the purpose of the oxidative burst during phagocytosis?
What is the main function of lysosomal proteases in phagocytes?
What is the main function of lysosomal proteases in phagocytes?
What happens to neutrophils in response to pathogens and inflammatory mediators?
What happens to neutrophils in response to pathogens and inflammatory mediators?
What is the cause of chronic granulomatous disease (CGD)?
What is the cause of chronic granulomatous disease (CGD)?
What is the potential downside of releasing enzymes and ROS into the extracellular space to kill microbes?
What is the potential downside of releasing enzymes and ROS into the extracellular space to kill microbes?
Flashcards
Phagocytosis
Phagocytosis
Neutrophils and macrophages engulf and destroy microbes through this process.
Phagocytic receptors
Phagocytic receptors
These receptors on phagocytes are key for recognizing and binding to microbes.
Respiratory burst
Respiratory burst
Phagocyte oxidase converts oxygen into superoxide and free radicals.
Inducible nitric oxide synthase (iNOS)
Inducible nitric oxide synthase (iNOS)
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Chronic granulomatous disease (CGD)
Chronic granulomatous disease (CGD)
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Neutrophil extracellular traps (NETs)
Neutrophil extracellular traps (NETs)
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Inflammation tissue injury
Inflammation tissue injury
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Phagocytosis particle size
Phagocytosis particle size
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Microbe-binding receptors
Microbe-binding receptors
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Oxidative burst
Oxidative burst
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Lysosomal proteases
Lysosomal proteases
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Neutrophil response to pathogens
Neutrophil response to pathogens
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Cause of chronic granulomatous disease (CGD)
Cause of chronic granulomatous disease (CGD)
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Extracellular enzyme/ROS downside
Extracellular enzyme/ROS downside
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