Phagocytosis Quiz
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Questions and Answers

Which of the following is the primary process by which neutrophils and macrophages destroy ingested microbes?

  • Pinocytosis
  • Phagocytosis (correct)
  • Endocytosis
  • Exocytosis
  • Which of the following are the principal phagocytic receptors on phagocytes?

  • Mannose receptors and other lectins
  • Receptors for antibodies and complement
  • Both A and B (correct)
  • None of the above
  • What is the process by which phagocyte oxidase converts molecular oxygen into superoxide anion and free radicals?

  • Phagolysosomal fusion
  • Respiratory burst (correct)
  • Oxidative burst
  • Phagocytosis
  • Which enzyme is responsible for converting arginine to nitric oxide in macrophages?

    <p>Inducible nitric oxide synthase (iNOS)</p> Signup and view all the answers

    What is the cause of chronic granulomatous disease (CGD)?

    <p>Inherited deficiency of phagocyte oxidase enzyme</p> Signup and view all the answers

    What is the purpose of neutrophil extracellular traps (NETs)?

    <p>To trap and kill bacteria and fungi</p> Signup and view all the answers

    What is the reason why inflammation may cause tissue injury?

    <p>The injury caused by enzymes and ROS liberated into the extracellular space</p> Signup and view all the answers

    What is the size range of particles that can be ingested through phagocytosis?

    <p>Between 0.5 μm and 1 μm in diameter</p> Signup and view all the answers

    What are the two types of receptors that can bind to microbes during phagocytosis?

    <p>Antibody receptors and complement receptors</p> Signup and view all the answers

    What is the purpose of the oxidative burst during phagocytosis?

    <p>To convert molecular oxygen into superoxide anion and free radicals</p> Signup and view all the answers

    What is the main function of lysosomal proteases in phagocytes?

    <p>Break down microbial proteins</p> Signup and view all the answers

    What happens to neutrophils in response to pathogens and inflammatory mediators?

    <p>They die and extrude their nuclear contents to form NETs</p> Signup and view all the answers

    What is the cause of chronic granulomatous disease (CGD)?

    <p>Inherited deficiency of the phagocyte oxidase enzyme</p> Signup and view all the answers

    What is the potential downside of releasing enzymes and ROS into the extracellular space to kill microbes?

    <p>They may injure host tissues</p> Signup and view all the answers

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