10 Questions
Which type of microbiota virulence factor is capable of digesting collagen, elastin, and components of the extracellular matrix?
Arg-1 protease produced by Porphyromonas gingivalis
Which microbial virulence factor has a great capacity to kill Leukocytes?
Arg-1 protease produced by Porphyromonas gingivalis
Which component of the host defense system acts as the first innate defense system?
Physical barriers
Which cells and proteins are part of the inflammatory response and recognize proteins and microorganisms as part of the innate defense system?
Leukocytes and polymorphonuclear cells
What do phagocytes do in the host defense system?
Attack and destroy harmful pathogens, and secrete cytokines to recruit other leukocytes
What is the main role of the host's immune system in the gingival tissues?
To produce a defense reaction against microorganisms that protects the dentogingival junction
What can result from an exaggerated immune reaction in the gingival tissues?
Bone destruction extending deeper into the connective tissue
What characterizes the host response in immunocompromised patients?
Weak response inadequate to battle the dental biofilm
What do microbial virulence factors directly do to host cells and tissues?
Injure host cells and tissues
In periodontal disease, what do virulence factors from subgingival microbiota primarily do?
Sustain factors produced by subgingival microbiota
Test your knowledge on the pathology of periodontal disease and the host-parasite interactions in gingival tissues. Understand the immune system's response to microbial attacks and its role in protecting the dentogingival junction.
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