Periodontics I Lesson 5: Pathology of Periodontal Disease Host-Parasite Interactions
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Questions and Answers

Which type of microbiota virulence factor is capable of digesting collagen, elastin, and components of the extracellular matrix?

  • Leukotoxin
  • Soluble enzymes
  • Arg-1 protease produced by Porphyromonas gingivalis (correct)
  • Harmful metabolic waste products
  • Which microbial virulence factor has a great capacity to kill Leukocytes?

  • Arg-1 protease produced by Porphyromonas gingivalis (correct)
  • Proteinases
  • Soluble enzymes
  • Lipopolysaccharides (LPS)
  • Which component of the host defense system acts as the first innate defense system?

  • Saliva and gingival crevicular fluid
  • Physical barriers (correct)
  • Phagocytes
  • Chemical barriers
  • Which cells and proteins are part of the inflammatory response and recognize proteins and microorganisms as part of the innate defense system?

    <p>Leukocytes and polymorphonuclear cells</p> Signup and view all the answers

    What do phagocytes do in the host defense system?

    <p>Attack and destroy harmful pathogens, and secrete cytokines to recruit other leukocytes</p> Signup and view all the answers

    What is the main role of the host's immune system in the gingival tissues?

    <p>To produce a defense reaction against microorganisms that protects the dentogingival junction</p> Signup and view all the answers

    What can result from an exaggerated immune reaction in the gingival tissues?

    <p>Bone destruction extending deeper into the connective tissue</p> Signup and view all the answers

    What characterizes the host response in immunocompromised patients?

    <p>Weak response inadequate to battle the dental biofilm</p> Signup and view all the answers

    What do microbial virulence factors directly do to host cells and tissues?

    <p>Injure host cells and tissues</p> Signup and view all the answers

    In periodontal disease, what do virulence factors from subgingival microbiota primarily do?

    <p>Sustain factors produced by subgingival microbiota</p> Signup and view all the answers

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