Hematologic System

Play an AI-generated podcast conversation about this lesson

What is the primary site of residence of hematopoietic stem cells in humans?

Liver

Red bone marrow (correct)

Spleen

Yellow bone marrow

Which type of blood cells are mainly produced in the red bone marrow?

White blood cells

Platelets

Plasma cells

Red blood cells (correct)

What is the approximate lifespan of erythrocytes in full-term infants?

60-80 days (correct)

90-100 days

10-20 days

30-40 days

What is the primary factor leading to polycythemia in newborns?

Increased erythropoietin production due to hypoxic intrauterine environment Signup and view all the answers

Which blood cell count is high at birth, then falls within or below normal adult range after 2 weeks?

Neutrophil count Signup and view all the answers

What is the main cause of differences in clotting factors between children and adults?

Decreased risk for thrombotic diseases and complications in children Signup and view all the answers

Which type of blood cell count is higher in children than in teenagers or adults?

Eosinophil count Signup and view all the answers

'Hematopoiesis' is the process of blood cell production primarily occurring in which organ?

Red bone marrow Signup and view all the answers

What stimulates the faster differentiation (maturing) of progenitor cells in hematopoiesis?

Erythropoietin Signup and view all the answers

Where are most of the thrombocytes stored in the body?

Peripheral blood Signup and view all the answers

What is the primary site for the production of erythropoietin?

Kidney Signup and view all the answers

What is the function of erythropoietin?

Increases RBC number within 24h Signup and view all the answers

What is the role of reticulocytes in erythropoiesis?

Contain polyribosomes and mitochondria for hemoglobin synthesis Signup and view all the answers

What factor increases hematopoiesis by stimulating faster proliferation (dividing) of stem cells into progenitor cells?

Conversion of yellow bone marrow to red marrow Signup and view all the answers

Where are matured blood cells stored before being released into the peripheral blood?

In walls around blood vessels Signup and view all the answers

What is the lifespan of erythropoietin in the plasma?

$4-12h$ Signup and view all the answers

What does an elevated retic count indicate?

New RBCs are being produced Signup and view all the answers

Which organ releases erythropoietin in response to low renal oxygenation?

Kidney Signup and view all the answers

What does an elevated erythropoietin level indicate?

Low renal oxygenation Signup and view all the answers

What is the primary function of reticulocytes?