20 Questions
Which enzyme is responsible for the conversion of PCr and ADP to creatine and ATP?
Creatine Kinase
What is the main source of PCr in the body?
Red meat
Where does the cytosolic isoform of creatine kinase prefer to break down PCr?
In the cytosol of the cell
What is the main function of the creatine-phosphate shuttle?
To transport PCr and Cr between the mitochondria and cytosol
Why is the creatine-phosphate shuttle necessary?
To maintain ATP levels
What happens to PCr levels during exercise?
They decrease
What happens to ATP levels during exercise?
They decrease
What is the main product of glycolysis?
Pyruvate
How many ATP molecules are produced in glycolysis?
4
What is the purpose of adenylate kinase?
To convert ATP to ADP
Which enzyme is responsible for the conversion of pyruvate to lactate?
Lactate Dehydrogenase (LDH)
Which fiber type produces more lactate?
Type 2 (fast twitch) fibers
What is the predominant fiber type in which LDH1-2 is found?
Type 1 (slow twitch) fibers
Which system is primarily responsible for ATP production during high intensity exercise?
Glycolysis
What happens to NAD+ during glycolysis?
It is converted into NADH
Which enzyme is responsible for the conversion of lactate to pyruvate?
Lactate Dehydrogenase (LDH)
What is the main source of ATP during the last 30 seconds of a short-distance race?
Glycolysis
What is the role of LDH1-5 in fast twitch muscle fibers?
To convert pyruvate into lactate
What is the main reason for lactate production during high intensity exercise?
Absence of oxygen
What happens to lactate in the body after exercise?
It is converted into glucose through gluconeogenesis
Test your knowledge on PCr (phosphocreatine) and its sources, its role as an energy buffer, the reversible reaction it undergoes with ATP, and the different isoforms of creatine kinase. Learn about the production of PCr in the liver, pancreas, and kidneys, as well as its dietary sources.
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