Creatine Kinase (CK) Function and Diagnostic Significance
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Questions and Answers

In which of the following tissues are CK levels the highest?

  • Skeletal muscle (correct)
  • Liver
  • Thyroid
  • Bladder
  • What is the main function of Creatine Kinase (CK)?

  • Assisting in ATP regeneration in muscle tissue (correct)
  • Aiding in digestion
  • Promoting bone growth
  • Regulating blood sugar levels
  • What is a diagnostic significance of elevated CK levels?

  • Anemia
  • High blood pressure
  • Muscular dystrophy (correct)
  • Respiratory infection
  • Which CK isoenzyme is a sensitive indicator of acute myocardial infarction (AMI)?

    <p>CKMB</p> Signup and view all the answers

    What is the preferred marker for myocardial infarction?

    <p>Troponin</p> Signup and view all the answers

    How is the measurement of CK isoenzymes typically carried out?

    <p>Electrophoresis, ion-exchange chromatography, radioimmunoassay (RIA), and immunoinhibition methods</p> Signup and view all the answers

    Which method is 6 times faster for measuring Creatine Kinase (CK) levels?

    <p>Oliver-Rosalki at pH 6.8</p> Signup and view all the answers

    Which tissue has the smallest CK levels?

    <p>Bladder</p> Signup and view all the answers

    What is the diagnostic significance of elevated CK BB levels?

    <p>Tumor marker for prostatic carcinoma</p> Signup and view all the answers

    Which CK isoenzyme is a rare tumor marker due to its hindered passage across the blood-brain barrier?

    <p>CKBB</p> Signup and view all the answers

    Which is the preferred marker for myocardial infarction?

    <p>Troponin</p> Signup and view all the answers

    In which disorder are CK levels frequently elevated due to the high concentrations of CK in muscle tissue?

    <p>Myocardial infarction (MI)</p> Signup and view all the answers

    Which method is NOT typically used for the measurement of CK isoenzymes?

    <p>Polymerase chain reaction (PCR)</p> Signup and view all the answers

    Which tissue does NOT have high levels of CK?

    <p>Pancreas</p> Signup and view all the answers

    What is the diagnostic significance of elevated CK BB levels?

    <p>Tumor marker for prostatic carcinoma</p> Signup and view all the answers

    Which CK isoenzyme is associated with disorders of cardiac and skeletal muscle due to its high concentrations in muscle tissue?

    <p>CKMM</p> Signup and view all the answers

    What is a sensitive indicator of acute myocardial infarction (AMI) and muscular dystrophy, specifically of Duchenne type?

    <p>CKMM</p> Signup and view all the answers

    In which disorder are CK levels frequently elevated due to the high concentrations of CK in muscle tissue?

    <p>All of the above</p> Signup and view all the answers

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