Pathophysiology Quiz: Atrophy, Hypertrophy, and Cell Changes
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Questions and Answers

Which of the following is a cause of atrophy?

  • Normal workload (correct)
  • Increased protein synthesis
  • Loss of innervations
  • Diminished blood supply
  • What term describes a reduction in the size of an organ or tissue resulting from a decrease in cell size?

  • Hypertrophy
  • Hyperplasia
  • Metaplasia
  • Atrophy (correct)
  • What is the main characteristic of hypertrophy?

  • Decrease in cell size
  • Increase in cell size (correct)
  • Replacement of one cell type by another
  • Increase in cell number
  • Which of the following is an example of physiologic hypertrophy?

    <p>Uterine hypertrophy during pregnancy</p> Signup and view all the answers

    Hyperplasia is defined as an increase in the __________ of cells in an organ or tissue.

    <p>Number</p> Signup and view all the answers

    Which of the following is a pathologic cause of hyperplasia?

    <p>Papilloma virus infection</p> Signup and view all the answers

    Barrett's esophagus is an example of metaplasia in which the lower esophageal epithelium transforms from?

    <p>Squamous to columnar epithelium</p> Signup and view all the answers

    Mesenchymal metaplasia is characterized by the transformation of __________ into osteoblasts or chondroblasts.

    <p>Fibroblasts</p> Signup and view all the answers

    Which of the following is NOT a histologic change associated with atrophy?

    <p>Increased cell number</p> Signup and view all the answers

    Which form of adaptation involves an increase in the size of cells and the organ?

    <p>Hypertrophy</p> Signup and view all the answers

    Which of the following is a pathologic cause of hypertrophy?

    <p>Acromegaly</p> Signup and view all the answers

    Which type of metaplasia is reversible?

    <p>Epithelial metaplasia</p> Signup and view all the answers

    Study Notes

    Cellular Adaptations

    • Atrophy is a reduction in the size of an organ or tissue resulting from a decrease in cell size.

    Hypertrophy

    • Characterized by an increase in the size of cells and the organ.
    • Example of physiologic hypertrophy: muscle hypertrophy in athletes.
    • Pathologic cause of hypertrophy: high blood pressure (hypertension) leading to cardiac hypertrophy.

    Hyperplasia

    • Defined as an increase in the number of cells in an organ or tissue.
    • Pathologic cause of hyperplasia: endometrial hyperplasia caused by prolonged exposure to estrogen.

    Metaplasia

    • Barrett's esophagus is an example of metaplasia, where the lower esophageal epithelium transforms from squamous epithelium to columnar epithelium.
    • Mesenchymal metaplasia is characterized by the transformation of fibroblasts into osteoblasts or chondroblasts.
    • Reversible type of metaplasia: squamous metaplasia.

    Atrophy

    • NOT a histologic change associated with atrophy: increase in the number of cells.

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    Description

    Test your knowledge of atrophy, hypertrophy, and cell changes with this quiz. Answer questions about the causes and characteristics of these physiological processes.

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