38 Questions
What is the normal range for INR in individuals not taking anticoagulation drugs?
1.1 or below
What is the primary mechanism of action of warfarin?
Inhibiting the action of vitamin K
What is the therapeutic class of warfarin?
Anticoagulant
What is the normal range for platelet counts in healthy individuals?
150,000-450,000
What is the primary nursing consideration for patients taking warfarin?
Monitoring for bleeding
What is the pharmacologic class of warfarin?
Vitamin K antagonist
What is the primary adverse effect of warfarin?
Bleeding
What is the pregnancy category of warfarin?
X
What is the purpose of overlapping heparin therapy with warfarin?
To ensure therapeutic anticoagulation
What is the primary mechanism of action of direct thrombin inhibitors?
Directly inhibiting thrombin
What is the main concern when administering anticoagulants to patients with liver impairment?
Elevated liver enzymes and bilirubin
What is the primary indication for the use of heparin?
Preventing excessive clotting within blood vessels
Why is protamine sulfate used in the treatment of overdose?
To neutralize heparin effects
What is the primary side effect of anticoagulants?
Bleeding
Why is it essential to monitor the patient's activated partial thromboplastin time (aPTT) when administering heparin?
To keep the value at 1.5 to 2 times the baseline
What is the contraindication for dabigatran?
Active bleeding
Why is it essential to wait at least 18 hours following the last dose of rivaroxaban to remove an epidural catheter?
To allow for the elimination of the drug from the system
What is the primary interaction between heparin and other medications?
Increased risk of bleeding
What is the purpose of monitoring the patient's CBC and liver function tests when administering rivaroxaban?
To monitor liver function and detect potential adverse effects
Which of the following anticoagulants acts by directly inhibiting thrombin?
Dabigatran
What is the primary mechanism of action of heparin?
Inactivate several clotting factors
Which of the following is a major adverse effect of heparin administration during spinal or epidural anesthesia?
Neurologic damage from hematoma
What is the primary interaction between dabigatran and other medications?
Increased risk of bleeding with other anticoagulants
What is the therapeutic class of rivaroxaban?
Anticoagulant
What is the primary nursing consideration for patients taking heparin?
Observe for bleeding
What laboratory value should be monitored when administering heparin?
Activated partial thromboplastin time (aPTT)
What is the treatment of overdose for dabigatran?
No antidote available
What is the primary adverse effect of rivaroxaban?
Bleeding
What is the contraindication for heparin administration?
Active internal bleeding
What is the primary action of warfarin on the synthesis of clotting factors?
Inhibits the synthesis of clotting factors II, VII, IX, and X
Which of the following is a contraindication for warfarin therapy?
Recent trauma
What is the purpose of monitoring PT levels in patients on warfarin therapy?
To monitor the effectiveness of warfarin therapy
Which of the following herbal medications may interact with warfarin?
Ginkgo
What is the normal range for aPTT in individuals not receiving heparin therapy?
30-40 seconds
What is the primary mechanism of action of warfarin?
Inhibiting the action of vitamin K
Which of the following laboratory values is used to monitor the effectiveness of warfarin therapy?
INR
What is the pregnancy category of warfarin?
X
Which of the following is an adverse effect of warfarin therapy?
Hepatitis
Test your knowledge of coagulation disorders, including thrombocytopenia, laboratory values, and oral anticoagulants like warfarin. This quiz covers the pathophysiology of bleeding disorders and their treatment.
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