PCC SOM 2026 Pharmacology and Therapeutics: Drugs Used in Coagulation Disorders Quiz

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Questions and Answers

What is the primary function of hemostasis?

  • To promote thrombosis
  • To repair vascular injuries
  • To limit blood loss (correct)
  • To maintain blood fluidity

What is a common cause of dysregulated hemostasis?

  • Regular exercise
  • Hereditary or acquired defects in the clotting mechanism (correct)
  • Healthy lifestyle choices
  • Excessive consumption of vitamin C

What is the association between atrial fibrillation and blood clot formation?

  • Decreased risk of occlusive stroke
  • Increased risk of occlusive stroke (correct)
  • No association with blood clot formation
  • Decreased risk of thrombosis

Why is the use of anticoagulants common in the older population?

<p>Due to high prevalence of chronic atrial fibrillation (C)</p> Signup and view all the answers

What represents a breakdown of the hemostatic mechanism?

<p>Excessive bleeding or thrombosis (C)</p> Signup and view all the answers

Which molecule synthesized from arachidonic acid within platelets is a potent vasoconstrictor and platelet activator?

<p>Thromboxane A2 (TXA2) (D)</p> Signup and view all the answers

Which substance released from platelet granules is a powerful inducer of platelet aggregation?

<p>Adenosine Diphosphate (ADP) (B)</p> Signup and view all the answers

What phenomenon results in the aggregation and formation of a platelet plug?

<p>Fibrin clot stabilization (A)</p> Signup and view all the answers

Which type of thrombi tends to form in the high flow rate and high shear force environment of arteries?

<p>White thrombi (D)</p> Signup and view all the answers

In patients with defects in the formation of the primary platelet plug, where do they typically bleed from with injury?

<p>Surface sites (e.g., gingiva, skin, heavy menses) (B)</p> Signup and view all the answers

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