10 Questions
What is the primary function of hemostasis?
To limit blood loss
What is a common cause of dysregulated hemostasis?
Hereditary or acquired defects in the clotting mechanism
What is the association between atrial fibrillation and blood clot formation?
Increased risk of occlusive stroke
Why is the use of anticoagulants common in the older population?
Due to high prevalence of chronic atrial fibrillation
What represents a breakdown of the hemostatic mechanism?
Excessive bleeding or thrombosis
Which molecule synthesized from arachidonic acid within platelets is a potent vasoconstrictor and platelet activator?
Thromboxane A2 (TXA2)
Which substance released from platelet granules is a powerful inducer of platelet aggregation?
Adenosine Diphosphate (ADP)
What phenomenon results in the aggregation and formation of a platelet plug?
Fibrin clot stabilization
Which type of thrombi tends to form in the high flow rate and high shear force environment of arteries?
White thrombi
In patients with defects in the formation of the primary platelet plug, where do they typically bleed from with injury?
Surface sites (e.g., gingiva, skin, heavy menses)
Test your knowledge on drugs used in coagulation disorders with this quiz based on the lecture by Dr. Dessi James Ojascastro. Explore topics like hemostasis, anticoagulant drugs, fibrinolytic drugs, antiplatelet agents, and drugs used in bleeding disorders.
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