Pathophysiology: DNA, Genes, and Chromosomes Overview

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16 Questions

What is the basic structural unit of DNA packaging in eukaryotes?

Nucleosome

Which process uses the information encoded in a gene to direct the assembly of a protein molecule?

Gene Expression

What is the segment of DNA that encodes proteins?

Genes

What are the coding regions of a gene called?

Exons

What are the base sequences for 'start' and 'stop,' and regions of DNA that function as promoters of gene transcription?

Promoter sequences

What determines the polypeptide formed in gene expression?

Nucleotide sequence in the gene

Which regulatory molecules act as transcription factors by binding to the promoter region and help turn specific genes 'on' or 'off'?

Hormones

How do activators function in terms of gene transcription?

Boost gene transcription

What is the term for groups of transcription factor binding sites that can turn a gene 'on' or 'off' in specific parts of the body?

Enhancers and silencers

How many pairs of chromosomes are present in each human cell?

23

What type of chromosomes do males have?

XY

During meiosis in humans, how many chromosomes do each sperm and ovum receive?

23

What refers to different forms of a gene at a specific location on paired chromosomes?

Allele

What do Punnett squares predict in terms of genetic inheritance?

Probability of inheritance

What type of mutation is characterized by a single nucleotide change in the DNA sequence?

Point mutation

What do congenital anomalies refer to?

Disorders present at birth

Learn about cell nucleus, chromosomes, DNA, and genes in the context of pathophysiology for health sciences. Understand the structure of nucleosome and the process of gene expression.

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