Pathophysiology Chapter 39: Disorders of the Male Genitourinary System
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Questions and Answers

What is the primary function of the somatic nerves in the male sexual response?

  • Regulate the autonomic nervous system
  • Control erection and ejaculation
  • Stimulate the sinusoidal spaces of the corpora cavernosa
  • Control sensation and contraction of muscles (correct)
  • Which part of the penis is highly concentrated with sensory nerves?

  • Corpus spongiosum
  • Corpora cavernosa
  • Shaft
  • Glans (correct)
  • Which nervous system is involved in controlling ejaculation during the male sexual response?

  • Autonomic nervous system (ANS)
  • Sympathetic nervous system (SNS) (correct)
  • Somatic nervous system (SNS)
  • Parasympathetic nervous system (PNS)
  • What is the term for the masses of erectile tissue in the shaft of the penis?

    <p>Cavernous sinuses</p> Signup and view all the answers

    Which of the following is NOT a part of the neural control of male sexual function?

    <p>Endocrine system</p> Signup and view all the answers

    What is the term for the process by which the penis becomes flaccid after sexual activity?

    <p>Detumescence</p> Signup and view all the answers

    What is the primary function of the ductile system in the male reproductive anatomy?

    <p>Storage, maturation, and transport of sperm</p> Signup and view all the answers

    Which of the following structures is derived from the peritoneum?

    <p>Tunica vaginalis</p> Signup and view all the answers

    What is the main function of the testes in the male reproductive system?

    <p>Production of androgens and sperm</p> Signup and view all the answers

    What is the primary hormone produced by the testes?

    <p>Testosterone</p> Signup and view all the answers

    What is the enzyme responsible for forming dihydrotestosterone from testosterone?

    <p>5-alpha reductase</p> Signup and view all the answers

    Which of the following structures contains spermatogonia and Sertoli cells?

    <p>Seminiferous tubules</p> Signup and view all the answers

    What is the function of the Leydig cells in the testes?

    <p>Production of androgens</p> Signup and view all the answers

    What is the other major function of the testes besides steroidogenesis?

    <p>Spermatogenesis</p> Signup and view all the answers

    What is the primary function of prostaglandins secreted by the seminal vesicles?

    <p>None of the above</p> Signup and view all the answers

    What is the primary characteristic of erectile dysfunction?

    <p>Inability to achieve and maintain an erection</p> Signup and view all the answers

    Which of the following is a cause of erectile dysfunction?

    <p>Therapeutic drugs</p> Signup and view all the answers

    Which of the following is NOT a component of the milky alkaline fluid secreted by the prostate gland?

    <p>Fructose</p> Signup and view all the answers

    What is the function of inhibin B?

    <p>Suppression of FSH secretion</p> Signup and view all the answers

    What is the goal of androgen replacement therapy in treating erectile dysfunction?

    <p>To replace deficient hormones</p> Signup and view all the answers

    What is the role of ABP in the process of spermatogenesis?

    <p>Initiation of spermatogenesis</p> Signup and view all the answers

    What is the role of LH in the regulation of spermatogenesis?

    <p>Stimulation of testosterone production</p> Signup and view all the answers

    What is the term for the twisting of the spermatic cord?

    <p>Testicular torsion</p> Signup and view all the answers

    Which of the following glands produces mucus-like secretions?

    <p>Bulbourethral glands</p> Signup and view all the answers

    What is the role of plasminogen activator in the process of spermatogenesis?

    <p>Detachment of mature spermatozoa from Sertoli cells</p> Signup and view all the answers

    What is the cause of intravaginal torsion?

    <p>Loose attachment between the epididymis and testis</p> Signup and view all the answers

    What is the primary function of the hypothalamus in the regulation of spermatogenesis?

    <p>Secretion of GnRH</p> Signup and view all the answers

    Which of the following is a type of drug used to treat erectile dysfunction?

    <p>PDE-5 inhibitors</p> Signup and view all the answers

    What is the name of the type of testicular torsion that occurs in prenatals or neonates during testicular descent?

    <p>Extravaginal torsion</p> Signup and view all the answers

    What is the term for the inflammation of the epididymis?

    <p>Epididymitis</p> Signup and view all the answers

    At what age range does testicular torsion typically occur?

    <p>8-18 years</p> Signup and view all the answers

    What is a common symptom of intravaginal torsion?

    <p>Nausea</p> Signup and view all the answers

    What is a characteristic clinical manifestation of testicular torsion?

    <p>Testis high in the scrotum with abnormal orientation</p> Signup and view all the answers

    What is the effective time frame for surgical treatment of testicular torsion?

    <p>Within 6 hours</p> Signup and view all the answers

    What is a type of childhood disorder that can affect the testes?

    <p>Hypospadias</p> Signup and view all the answers

    Where do the testes develop from during embryonic development?

    <p>Embryonic kidneys</p> Signup and view all the answers

    What is a complication of untreated testicular torsion?

    <p>Infertility</p> Signup and view all the answers

    What is the purpose of prophylactic fixation of the unaffected testis in testicular torsion?

    <p>To prevent further torsion</p> Signup and view all the answers

    Study Notes

    Male Reproductive Anatomy

    • Testes: produce androgens and sperm
    • Ductile system: stores, matures, and transports sperm
    • Accessory genital organs: produce seminal fluid
    • Penis: eliminates urine and performs sexual functions
    • Histology of testes:
      • Tunica vaginalis: derived from the peritoneum
      • Tunic albuginea: dense connective capsule that forms the septa around the lobules inside the testis
      • Seminiferous tubules: contain spermatogonia and Sertoli cells
      • Connective tissue stroma: contains Leydig cells

    Testicular Function

    • 2 main functions:
      • Steroidogenesis
      • Spermatogenesis

    Androgens

    • Testosterone: main testicular hormone
    • Dihydrotestosterone: formed from testosterone in peripheral tissues, produced by the enzyme 5-alpha reductase
    • Androstenedione: produced by the testes
    • Estrogen: produced in small amounts

    Accessory Genital Glands

    • Paired seminal vesicles: secrete fructose, prostaglandins, proteins, and other substances
    • Prostate gland: secretes milky alkaline fluid containing citric acid, calcium, acid phosphate, a clotting enzyme, and profibrinolysin
    • Paired bulbourethral glands: produce mucus-like secretions

    Hypothalamic-Pituitary-Testicular Axis

    • Hypothalamus: regulates GnRH secretion
    • Pituitary: regulates LH and FSH secretion
    • Testes: produce testosterone and sperm in response to LH and FSH
    • Inhibin: produced by Sertoli cells, suppresses FSH secretion
    • ABP: androgen-binding protein, acts in epididymis to promote maturation of spermatozoa

    Erection and Sexual Function

    • Erection: vasodilation fills spongy tissue with blood
    • Neural innervation:
      • Sensory nerves in penis: mostly concentrated in the glans
      • Motor nerves: ANS (caverous nerves) controls erection, ejaculation, and detumescence, while somatic nerves (pudendal nerve) control sensation and contraction of muscles
    • Shaft: 3 masses of erectile tissue that are cavernous sinuses, including 2 corpora cavernosa and 1 corpus spongiosum
    • Male sex act involves interaction between spinal cord reflexes, higher neural centers, and the vascular system

    Testicular Disorders

    • Varicocele: dilation of the pampiniform plexus
    • Hydrocele: fluid accumulation in the tunica vaginalis
    • Testicular torsion: twisting of the spermatic cord, can be extra- or intravaginal
    • Inflammations: epididymitis, orchitis
    • Testicular torsion symptoms:
      • Nausea
      • Vomiting
      • Tacchycardia
      • Large tender testis
      • Pain radiating to the inguinal area
      • Thickening of the spermatic cord
      • Scrotal swelling
    • Clinical manifestations of testicular torsion:
      • Testis high in the scrotum with abnormal orientation
      • Scrotal swelling
      • Absence of the Cremasteric reflex
    • Treatment of testicular torsion: surgery (effective within 6 hours) involving detorsion or orchiectomy, with prophylactic fixation of the unaffected testis

    Childhood Disorders

    • Hypospadias
    • Epispadias
    • Phimosis
    • Paraphimosis
    • Cryptorchidism: failure of testicular descent

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    Description

    This quiz covers chapter 39 of Pathophysiology, focusing on disorders of the male genitourinary system. It is part of the BIO 218 course at the American University of Iraq - Baghdad. Topics include the male reproductive system and its disorders.

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