Pathophysiology BP204T: Heart Failure & Asthma

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Questions and Answers

Which of the following is a common etiological factor contributing to both congestive heart failure and hypertension?

  • Chronic kidney disease leading to fluid overload and increased renin production. (correct)
  • Increased levels of natriuretic peptides.
  • Vasodilation caused by nitric oxide deficiency.
  • Decreased sympathetic nervous system activity.

In the context of congestive heart failure, what is the primary pathophysiological mechanism that leads to pulmonary edema?

  • Increased systemic vascular resistance causing fluid to shift into the lungs.
  • Right ventricular failure causing backflow into the pulmonary circulation.
  • Decreased oncotic pressure in pulmonary capillaries.
  • Left ventricular dysfunction resulting in increased pulmonary venous pressure. (correct)

Which of the following compensatory mechanisms in heart failure eventually becomes maladaptive, contributing to disease progression?

  • Vasodilation of peripheral blood vessels.
  • Increased heart rate and contractility via sympathetic nervous system activation. (correct)
  • Decreased afterload on the heart.
  • Reduced secretion of atrial natriuretic peptide (ANP).

What is the role of chronic inflammation in the pathophysiology of bronchial asthma?

<p>It causes structural changes in the airways, such as remodeling and hyperresponsiveness. (A)</p> Signup and view all the answers

Which of the following best describes the pathophysiology of hypertension?

<p>It involves a complex interplay of genetic, environmental, and regulatory factors affecting blood volume and vascular resistance. (C)</p> Signup and view all the answers

In bronchial asthma, what is the immediate effect of mast cell degranulation following exposure to an allergen?

<p>Release of histamine and other mediators, leading to bronchoconstriction and inflammation. (B)</p> Signup and view all the answers

Which of the following is a significant long-term complication of uncontrolled hypertension?

<p>End-organ damage, including nephropathy and retinopathy. (D)</p> Signup and view all the answers

What role do leukotrienes play in the pathophysiology of bronchial asthma?

<p>They mediate bronchoconstriction, increase vascular permeability, and enhance mucus production. (A)</p> Signup and view all the answers

Which statement accurately contrasts the remodeling processes in congestive heart failure and bronchial asthma?

<p>Heart failure involves ventricular hypertrophy, while asthma involves airway wall thickening. (B)</p> Signup and view all the answers

How does increased afterload contribute to the pathophysiology of congestive heart failure?

<p>It increases the resistance against which the left ventricle must pump, leading to decreased stroke volume and potential heart failure. (A)</p> Signup and view all the answers

Flashcards

What is Pathophysiology?

The study of the physiological processes underlying disease.

What is Bronchial Asthma?

A chronic inflammatory disorder of the airways, causing airflow obstruction.

What is Etiology?

The causes or origins of a disease or abnormal condition.

What is Pathophysiology?

The functional changes associated with a disease or injury.

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What is Congestive Heart Failure (CHF)?

A condition where the heart can't pump enough blood to meet the body's needs.

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What is Hypertension?

Abnormally high blood pressure.

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Study Notes

  • This is the Pathophysiology Assignment 01, for Bachelor of Pharmacy students at Jharkhand Rai University.
  • The course code is BP204T.
  • The assignment is worth 20 marks.
  • Semester: Second
  • Time: 2 mins

Question 1

  • Question asks for the etiology and pathophysiology of:
    • Congestive Heart Failure
    • Hypertension
  • This question tests Bloom's Taxonomy Level 2: Understand.
  • It is worth 10 marks
  • CO2

Question 2

  • Question asks for the meaning of Pathophysiology and requires a detailed note on the pathophysiology of Bronchial Asthma.
  • Bloom's Taxonomy Level 2: Understand is being assessed.
  • It is worth 10 marks
  • CO2

Overall Assignment

  • Questions 1 and 2, assess the Understand (BTL 2) competence level.
  • The total marks allotted for both questions is 20, which accounts for 100% of the assignment's marks.

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