Pathology of Thyroid Gland: Goitre Definition, Types, and Morphology

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12 Questions

What is the pathogenesis of simple goitre?

Symmetrical diffuse enlargement of follicular cells

Which type of goitre is characterized by asymmetrical, nodular enlargement and irregular thyroid surface?

Multinodular goitre

What is the characteristic microscopic feature of multinodular goitre?

Variable sized nodules separated by fibrous tissue

What can repeated cycles of iodine deficiency and correction lead to in the thyroid?

Symmetrical diffuse enlargement

What is the primary cause of non-toxic endemic goitre?

Increased demands during pregnancy, lactation, and puberty

Which type of goitre is mostly caused by impaired thyroid hormone synthesis due to iodine deficiency?

Endemic goitre

What is the primary pathogenesis of diffuse colloid (simple) goitre?

Impaired synthesis of thyroid hormones due to iodine deficiency

Which factor is a common cause of sporadic non-toxic goitre in young females?

Ingestion of substances like cabbage and cauliflower

What is the specific feature of Graves disease that distinguishes it from other causes of hyperthyroidism?

Exophthalmos

Which of the following is a characteristic feature of Hashimoto’s thyroiditis?

Atrophic follicles with intense lymphocytic infiltration

What is the distinguishing feature of Subacute Granulomatous Thyroiditis?

Transient self-limited nature

Which neoplastic condition is associated with the development of goitre?

Papillary thyroid carcinomas

This quiz covers the pathology of the thyroid gland, focusing on the definition of goitre, types of goitre, and the morphology of different forms of goitre. It also includes a case study of a 33-year-old woman with symptoms related to thyroid dysfunction.

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