L7 (T1): Histology and pathology of the Endocrine system
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Questions and Answers

Which gland is divided into adenohypophysis and neurohypophysis?

  • Adrenal gland
  • Thyroid gland
  • Pancreas
  • Pituitary gland (correct)
  • Which type of cells in the anterior pituitary gland take up acidic dyes?

  • Acidophils (correct)
  • Follicles
  • Chromophobes
  • Basophils
  • Which hormone is secreted by both chromophobes and basophils in the pituitary gland?

  • Growth hormone (GH)
  • Thyroid stimulating hormone (TSH)
  • Adrenocorticotrophic hormone (ACTH) (correct)
  • Prolactin
  • Which hormone from the anterior pituitary gland stimulates bone growth?

    <p>Growth hormone (GH)</p> Signup and view all the answers

    Which hormone from the posterior pituitary gland facilitates the absorption of water in the kidneys?

    <p>Antidiuretic hormone (ADH)</p> Signup and view all the answers

    What condition is characterized by an enlarged thyroid gland due to hyperplasia and hypertrophy of thyroid cells?

    <p>Goitre</p> Signup and view all the answers

    Which disease is characterized by hypothyroidism and an enlarged thyroid gland?

    <p>Hashimoto's disease</p> Signup and view all the answers

    What is the main function of thyroxine (T4) and triiodothyronine (T3) synthesized by the thyroid gland?

    <p>Stimulate metabolic rate</p> Signup and view all the answers

    What is the term for a benign tumor arising from the anterior lobe of the pituitary gland?

    <p>Adenoma</p> Signup and view all the answers

    What is the term for a tumor that causes pressure effect and can be associated with overproduction of hormones?

    <p>Adenoma</p> Signup and view all the answers

    Which condition is characterized by diffuse enlargement of the thyroid gland due to hyperplasia of thyroid cells?

    <p>Grave's Disease</p> Signup and view all the answers

    What is the most common cause of hypothyroidism in areas where iodine is readily available?

    <p>Hashimoto's Thyroiditis</p> Signup and view all the answers

    Which condition is characterized by the immune system destroying its own thyroid tissue, leading to progressive depletion of thyroid cells and fibrosis?

    <p>Hashimoto's Thyroiditis</p> Signup and view all the answers

    Which type of thyroid carcinoma is associated with an increased risk of lymph node metastasis?

    <p>Papillary</p> Signup and view all the answers

    Which type of thyroid carcinoma has an increased risk of metastasis to bone, lung, and liver?

    <p>Follicular</p> Signup and view all the answers

    Which type of thyroid carcinoma arises from C cells and is associated with multiple endocrine neoplasm (MEN 2) syndrome?

    <p>Medullary</p> Signup and view all the answers

    Which condition is characterized by the accumulation of soft tissue and inflammatory cells behind the eye, leading to proptosis?

    <p>Grave's Disease</p> Signup and view all the answers

    Which condition is characterized by the thickening and induration of the skin on the anterior shin, known as pre-tibial myxoedema?

    <p>Grave's Disease</p> Signup and view all the answers

    What is the term for the benign tumour of the thyroid follicular cells?

    <p>Follicular adenoma</p> Signup and view all the answers

    What is the term for the softening of the trachea, which collapses and obstructs the airways?

    <p>Tracheomalacia</p> Signup and view all the answers

    Which of the following is NOT a learning objective mentioned in the text?

    <p>Learning the basic pathology of the major endocrine glands</p> Signup and view all the answers

    What is the meaning of the term 'hormone' in Greek?

    <p>To arouse</p> Signup and view all the answers

    Which gland is mentioned as both an exocrine and endocrine gland?

    <p>Pancreas</p> Signup and view all the answers

    What is the term for the action of a hormone on a target organ away from the secreting cell?

    <p>Endocrine</p> Signup and view all the answers

    Which type of gland is stimulated by neural stimulation to secrete hormones?

    <p>Adrenal gland</p> Signup and view all the answers

    What is the overall structure of endocrine glands?

    <p>Cuboidal secretory cells supported by myoepithelial cells</p> Signup and view all the answers

    Which glands mentioned in the text do not have lumina in their functional units?

    <p>Pituitary and parathyroid glands</p> Signup and view all the answers

    What is the topic of the text?

    <p>Histology and pathology of the endocrine system</p> Signup and view all the answers

    What is the email address of Catherine Chinyama mentioned in the text?

    <p><a href="mailto:[email protected]">[email protected]</a></p> Signup and view all the answers

    When was the text published?

    <p>6th January 2023</p> Signup and view all the answers

    Which of the following is NOT a learning objective mentioned in the text?

    <p>Learning the clinical details of the endocrine system</p> Signup and view all the answers

    What is the term for a tumor that causes pressure effect and can be associated with overproduction of hormones?

    <p>Adenoma</p> Signup and view all the answers

    Which hormone from the posterior pituitary gland facilitates the absorption of water in the kidneys?

    <p>Antidiuretic hormone (ADH)</p> Signup and view all the answers

    Which type of thyroid carcinoma is associated with an increased risk of lymph node metastasis?

    <p>Papillary carcinoma</p> Signup and view all the answers

    Which hormones are secreted by the posterior pituitary gland?

    <p>Antidiabetic hormone and oxytocin</p> Signup and view all the answers

    What is the function of antidiabetic hormone (ADH) secreted by the posterior pituitary gland?

    <p>Facilitates absorption of water in the kidneys</p> Signup and view all the answers

    What is oxytocin's role in the body?

    <p>Promotes contraction of smooth muscle in the uterus</p> Signup and view all the answers

    How do we identify the specific hormones secreted by cells in the pituitary gland?

    <p>By using antibody staining against specific hormones</p> Signup and view all the answers

    Which of the following is NOT a hormone produced by the anterior pituitary gland?

    <p>Vasopressin</p> Signup and view all the answers

    What is the term for the action of a hormone on an adjacent cell?

    <p>Paracrine</p> Signup and view all the answers

    Which of the following glands mentioned in the text does NOT have a lumen in its functional unit?

    <p>Parathyroid glands</p> Signup and view all the answers

    Which hormone produced by the anterior pituitary gland acts on the breast?

    <p>Prolactin</p> Signup and view all the answers

    Which gland is referred to as the 'father' of the endocrine glands?

    <p>Pituitary gland</p> Signup and view all the answers

    What is the term for the condition characterized by the accumulation of soft tissue and inflammatory cells behind the eye, leading to proptosis?

    <p>Graves' disease</p> Signup and view all the answers

    What is the term for the enlargement of the thyroid gland due to hyperplasia of thyroid cells?

    <p>Goitre</p> Signup and view all the answers

    Which hormone from the anterior pituitary gland stimulates bone growth?

    <p>Growth hormone (GH)</p> Signup and view all the answers

    Which condition is characterized by the enlargement of the thyroid gland due to hyperplasia and hypertrophy of thyroid cells?

    <p>Goitre</p> Signup and view all the answers

    What is the term for the benign tumor arising from the anterior lobe of the pituitary gland?

    <p>Adenoma</p> Signup and view all the answers

    Which hormone deficiency leads to the enlargement of the thyroid gland in patients with goitre?

    <p>Thyroid-stimulating hormone (TSH)</p> Signup and view all the answers

    What is the term for the softening of the trachea, which collapses and obstructs the airways in patients with goitre?

    <p>Tracheomalacia</p> Signup and view all the answers

    Which condition is characterized by the accumulation of soft tissue and inflammatory cells behind the eyes, leading to proptosis?

    <p>Graves Disease</p> Signup and view all the answers

    What is the term for a benign tumor arising from the anterior lobe of the pituitary gland?

    <p>Adenoma</p> Signup and view all the answers

    Which type of thyroid carcinoma has an increased risk of metastasis to bone, lung, and liver?

    <p>Follicular Thyroid Carcinoma</p> Signup and view all the answers

    What is the term for the softening of the trachea, which collapses and obstructs the airways?

    <p>Tracheomalacia</p> Signup and view all the answers

    Which term is used to describe the thickening and integration of the anterior skin in infiltrated democracy?

    <p>Mixed oedema</p> Signup and view all the answers

    What is the biochemical characteristic of patients with good law to search and how to three and two for due to the negative feedback?

    <p>Normal thyroid function</p> Signup and view all the answers

    What is the appearance of the thyroid gland in patients with Grave's disease?

    <p>Enlarged and vascular</p> Signup and view all the answers

    What is the main reason why appropriate medication is used to suppress the production of excess to 24 in patients with thyroid gland abnormalities?

    <p>To regulate hormone levels</p> Signup and view all the answers

    What is the characteristic feature of thyroid glands with excessive 24 production?

    <p>Permanent blood vessels</p> Signup and view all the answers

    What is the term used to describe the accumulation of soft tissue and inflammatory cells behind the eye in thyroid gland abnormalities?

    <p>Proptosis</p> Signup and view all the answers

    Study Notes

    Pituitary Gland

    • The pituitary gland is divided into adenohypophysis and neurohypophysis.
    • Basophils in the anterior pituitary gland take up acidic dyes.
    • Chromophobes and basophils in the pituitary gland secrete growth hormone.
    • Growth hormone from the anterior pituitary gland stimulates bone growth.
    • Vasopressin (ADH) from the posterior pituitary gland facilitates the absorption of water in the kidneys.

    Thyroid Gland

    • Goitre is a condition characterized by an enlarged thyroid gland due to hyperplasia and hypertrophy of thyroid cells.
    • Thyroid hormones (T3 and T4) synthesized by the thyroid gland regulate metabolism.
    • A benign tumor arising from the anterior lobe of the pituitary gland is called a pituitary adenoma.
    • A tumor that causes pressure effect and can be associated with overproduction of hormones is called a space-occupying lesion.
    • Graves' disease is characterized by diffuse enlargement of the thyroid gland due to hyperplasia of thyroid cells.
    • Autoimmune thyroiditis is a condition where the immune system destroys its own thyroid tissue, leading to progressive depletion of thyroid cells and fibrosis.
    • Papillary thyroid carcinoma is associated with an increased risk of lymph node metastasis.
    • Follicular thyroid carcinoma has an increased risk of metastasis to bone, lung, and liver.
    • Medullary thyroid carcinoma arises from C cells and is associated with multiple endocrine neoplasm (MEN 2) syndrome.
    • Thyroid follicular adenoma is a benign tumor of the thyroid follicular cells.
    • Tracheomalacia is the softening of the trachea, which collapses and obstructs the airways.
    • Pretibial myxoedema is a condition characterized by the thickening and induration of the skin on the anterior shin.
    • Exophthalmos is a condition characterized by the accumulation of soft tissue and inflammatory cells behind the eye, leading to proptosis.

    General Endocrinology

    • Hormone from Greek means "to stimulate" or "to excite".
    • The pancreas is mentioned as both an exocrine and endocrine gland.
    • The action of a hormone on a target organ away from the secreting cell is called endocrine action.
    • Neural stimulation stimulates the secretion of hormones in certain glands.
    • The overall structure of endocrine glands is compact, epithelial cells, and richly vascularized.
    • The pituitary gland, thyroid gland, and adrenal glands mentioned in the text do not have lumina in their functional units.

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    Description

    Test your knowledge of the histology and pathology of the endocrine system with this quiz. Learn about the relationship between endocrine glands and target organs, the types of hormones secreted by major endocrine glands, and the histological features of these glands.

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