28 Questions
What is the primary characteristic of fatty change or steatosis?
The abnormal reversible accumulation of triglycerides within the cytoplasm of cells
What is the primary cause of high cholesterol levels in the blood in familial hypercholesterolemia?
Genetic mutations affecting lipid metabolism
Which condition is characterized by the deposition of cholesterol in arterial walls?
Atherosclerosis
What is the term for the accumulation of cholesterol within cells?
Cholesterol accumulation
What is the term for the visible accumulation of cholesterol in the skin, often seen in conditions like atherosclerosis?
Xanthoma
What is the term for the excessive deposition of mucin, a glycoprotein that forms the major constituent of mucus, within cells or tissues?
Mucin accumulation
Which of the following is NOT a cause of hyalinosis?
Hypothyroidism
What is the characteristic appearance of amyloid protein accumulation under polarized light?
Apple-green birefringence
Which of the following conditions is associated with the accumulation of mucin in the dermis?
Mucinosis
What is the term for the deposition of a homogenous, glassy, pink material within cells or in the extracellular space?
Hyaline accumulation
Which of the following is a typical cause of myxomatous degeneration?
Age-related changes in connective tissue
What is the underlying mechanism of brown atrophy of the heart?
Oxidative stress and cellular senescence
Which of the following is a characteristic of lead poisoning?
Black pigmentation of the gums
What is the primary cause of carbon poisoning?
Inhalation of carbon monoxide gas
Which of the following is a characteristic of anthracosis?
Black carbon particles within macrophages
What is the underlying mechanism of uric acid accumulation?
Production of too much uric acid or excretion of too little
Which of the following is a potential consequence of uric acid accumulation?
Renal damage and kidney stones
What is the term for the disease involving accumulation of excess hemosiderin?
Hemosiderosis
Which of the following is NOT a cause of jaundice?
Addison's disease
What is the term for the pigment responsible for skin pigmentation?
Melanin
What is the term for the iron-free pigment that increases in the liver in case of jaundice?
Bilirubin
What is the term for the accumulation of lipofuscin in cells, often referred to as the 'wear and tear' pigment?
Cellular aging
What is the genetic disorder of iron absorption that causes hemochromatosis?
Genetic disorder of iron absorption
What is the primary factor that contributes to the accumulation of MSU crystals?
Consumption of foods high in purines
What is the term that describes the deposition of calcium salts in damaged or necrotic tissues?
Dystrophic calcification
Which of the following is NOT a cause of metastatic calcification?
Reduced kidney function
What is the characteristic appearance of calcium deposits under polarized light?
Bright, refractile areas
What is the term that describes the destruction of bone tissue by malignant tumors?
Bone destruction
Learn about fatty change, steatosis, and cholesterol accumulation in cells, including causes and conditions like atherosclerosis, alcoholism, and diabetes. Test your knowledge of intracellular accumulation and extracellular deposition in this lab quiz.
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