Pathology Lab 7: Intracellular Accumulation and Deposition

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Questions and Answers

What is the primary characteristic of fatty change or steatosis?

  • The deposition of lipids in arterial walls
  • The accumulation of cholesterol within the cytoplasm of cells
  • The abnormal reversible accumulation of triglycerides within the cytoplasm of cells (correct)
  • The buildup of saturated fats in the bloodstream

What is the primary cause of high cholesterol levels in the blood in familial hypercholesterolemia?

  • Abnormalities in liver function
  • High dietary intake of saturated fats and cholesterol-rich foods
  • Impaired pancreatic function
  • Genetic mutations affecting lipid metabolism (correct)

Which condition is characterized by the deposition of cholesterol in arterial walls?

  • Obesity
  • Atherosclerosis (correct)
  • Diabetes mellitus
  • Steatosis

What is the term for the accumulation of cholesterol within cells?

<p>Cholesterol accumulation (B)</p> Signup and view all the answers

What is the term for the visible accumulation of cholesterol in the skin, often seen in conditions like atherosclerosis?

<p>Xanthoma (D)</p> Signup and view all the answers

What is the term for the excessive deposition of mucin, a glycoprotein that forms the major constituent of mucus, within cells or tissues?

<p>Mucin accumulation (D)</p> Signup and view all the answers

Which of the following is NOT a cause of hyalinosis?

<p>Hypothyroidism (A)</p> Signup and view all the answers

What is the characteristic appearance of amyloid protein accumulation under polarized light?

<p>Apple-green birefringence (C)</p> Signup and view all the answers

Which of the following conditions is associated with the accumulation of mucin in the dermis?

<p>Mucinosis (D)</p> Signup and view all the answers

What is the term for the deposition of a homogenous, glassy, pink material within cells or in the extracellular space?

<p>Hyaline accumulation (D)</p> Signup and view all the answers

Which of the following is a typical cause of myxomatous degeneration?

<p>Age-related changes in connective tissue (D)</p> Signup and view all the answers

What is the underlying mechanism of brown atrophy of the heart?

<p>Oxidative stress and cellular senescence (D)</p> Signup and view all the answers

Which of the following is a characteristic of lead poisoning?

<p>Black pigmentation of the gums (A)</p> Signup and view all the answers

What is the primary cause of carbon poisoning?

<p>Inhalation of carbon monoxide gas (C)</p> Signup and view all the answers

Which of the following is a characteristic of anthracosis?

<p>Black carbon particles within macrophages (D)</p> Signup and view all the answers

What is the underlying mechanism of uric acid accumulation?

<p>Production of too much uric acid or excretion of too little (A)</p> Signup and view all the answers

Which of the following is a potential consequence of uric acid accumulation?

<p>Renal damage and kidney stones (B)</p> Signup and view all the answers

What is the term for the disease involving accumulation of excess hemosiderin?

<p>Hemosiderosis (D)</p> Signup and view all the answers

Which of the following is NOT a cause of jaundice?

<p>Addison's disease (B)</p> Signup and view all the answers

What is the term for the pigment responsible for skin pigmentation?

<p>Melanin (D)</p> Signup and view all the answers

What is the term for the iron-free pigment that increases in the liver in case of jaundice?

<p>Bilirubin (B)</p> Signup and view all the answers

What is the term for the accumulation of lipofuscin in cells, often referred to as the 'wear and tear' pigment?

<p>Cellular aging (A)</p> Signup and view all the answers

What is the genetic disorder of iron absorption that causes hemochromatosis?

<p>Genetic disorder of iron absorption (C)</p> Signup and view all the answers

What is the primary factor that contributes to the accumulation of MSU crystals?

<p>Consumption of foods high in purines (D)</p> Signup and view all the answers

What is the term that describes the deposition of calcium salts in damaged or necrotic tissues?

<p>Dystrophic calcification (C)</p> Signup and view all the answers

Which of the following is NOT a cause of metastatic calcification?

<p>Reduced kidney function (D)</p> Signup and view all the answers

What is the characteristic appearance of calcium deposits under polarized light?

<p>Bright, refractile areas (D)</p> Signup and view all the answers

What is the term that describes the destruction of bone tissue by malignant tumors?

<p>Bone destruction (A)</p> Signup and view all the answers

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