Pathology Lab 7: Intracellular Accumulation and Deposition

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What is the primary characteristic of fatty change or steatosis?

The deposition of lipids in arterial walls

The accumulation of cholesterol within the cytoplasm of cells

The abnormal reversible accumulation of triglycerides within the cytoplasm of cells (correct)

The buildup of saturated fats in the bloodstream

What is the primary cause of high cholesterol levels in the blood in familial hypercholesterolemia?

Abnormalities in liver function

High dietary intake of saturated fats and cholesterol-rich foods

Impaired pancreatic function

Genetic mutations affecting lipid metabolism (correct)

Which condition is characterized by the deposition of cholesterol in arterial walls?

Obesity

Atherosclerosis (correct)

Diabetes mellitus

Steatosis

What is the term for the accumulation of cholesterol within cells?

Cholesterol accumulation Signup and view all the answers

What is the term for the visible accumulation of cholesterol in the skin, often seen in conditions like atherosclerosis?

Xanthoma Signup and view all the answers

What is the term for the excessive deposition of mucin, a glycoprotein that forms the major constituent of mucus, within cells or tissues?

Mucin accumulation Signup and view all the answers

Which of the following is NOT a cause of hyalinosis?

Hypothyroidism Signup and view all the answers

What is the characteristic appearance of amyloid protein accumulation under polarized light?

Apple-green birefringence Signup and view all the answers

Which of the following conditions is associated with the accumulation of mucin in the dermis?

Mucinosis Signup and view all the answers

What is the term for the deposition of a homogenous, glassy, pink material within cells or in the extracellular space?

Hyaline accumulation Signup and view all the answers

Which of the following is a typical cause of myxomatous degeneration?

Age-related changes in connective tissue Signup and view all the answers

What is the underlying mechanism of brown atrophy of the heart?

Oxidative stress and cellular senescence Signup and view all the answers

Which of the following is a characteristic of lead poisoning?

Black pigmentation of the gums Signup and view all the answers

What is the primary cause of carbon poisoning?

Inhalation of carbon monoxide gas Signup and view all the answers

Which of the following is a characteristic of anthracosis?

Black carbon particles within macrophages Signup and view all the answers

What is the underlying mechanism of uric acid accumulation?

Production of too much uric acid or excretion of too little Signup and view all the answers

Which of the following is a potential consequence of uric acid accumulation?

Renal damage and kidney stones Signup and view all the answers

What is the term for the disease involving accumulation of excess hemosiderin?

Hemosiderosis Signup and view all the answers

Which of the following is NOT a cause of jaundice?

Addison's disease Signup and view all the answers

What is the term for the pigment responsible for skin pigmentation?

Melanin Signup and view all the answers

What is the term for the iron-free pigment that increases in the liver in case of jaundice?

Bilirubin Signup and view all the answers

What is the term for the accumulation of lipofuscin in cells, often referred to as the 'wear and tear' pigment?

Cellular aging Signup and view all the answers

What is the genetic disorder of iron absorption that causes hemochromatosis?

Genetic disorder of iron absorption Signup and view all the answers

What is the primary factor that contributes to the accumulation of MSU crystals?

Consumption of foods high in purines Signup and view all the answers

What is the term that describes the deposition of calcium salts in damaged or necrotic tissues?

Dystrophic calcification Signup and view all the answers

Which of the following is NOT a cause of metastatic calcification?

Reduced kidney function Signup and view all the answers

What is the characteristic appearance of calcium deposits under polarized light?

Bright, refractile areas Signup and view all the answers

What is the term that describes the destruction of bone tissue by malignant tumors?

Bone destruction Signup and view all the answers