Pathology L5: Cell Adaptation and Homeostasis
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Questions and Answers

What is the primary consequence if a cell fails to adapt to stress?

  • The cell will experience cellular injury. (correct)
  • The cell will undergo hyperplasia.
  • The cell will maintain its normal function.
  • The cell will stabilize through homeostasis.
  • Which of the following types of adaptation is characterized by an increase in cell size?

  • Metaplasia
  • Hypertrophy (correct)
  • Dysplasia
  • Atrophy
  • Which type of cellular adaptation involves an increase in the number of cells?

  • Atrophy
  • Dysplasia
  • Hyperplasia (correct)
  • Metaplasia
  • What defines homeostasis in relation to cellular function?

    <p>The tendency for an organism to maintain stability in normal body states.</p> Signup and view all the answers

    Which of the following adaptations is not considered a minor type?

    <p>Dysfunction</p> Signup and view all the answers

    Which of the following statements regarding cell adaption is false?

    <p>It has an irreversible change</p> Signup and view all the answers

    What are the five minor types of adaption?

    <p>Atrophy, hypertrophy, hyperplasia, dysplasia and metaplasia</p> Signup and view all the answers

    Which factor does NOT contribute to cellular atrophy?

    <p>Increased protein synthesis</p> Signup and view all the answers

    What is an example of physiological atrophy?

    <p>Non-lactating mammary gland post pregnancy</p> Signup and view all the answers

    Which of the following correctly explains the role of denervation in cellular atrophy?

    <p>It leads to a decrease in cell function due to loss of nerve supply</p> Signup and view all the answers

    List some common causes of atrophy (hint 6 in class)

    <p>Decrease workload, denervation, decrease in blood supply or oxygen, inadequate nutrition, loss of endocrine function, aging (senescence)</p> Signup and view all the answers

    What is the primary distinction between hypoplasia and atrophy?

    <p>Hypoplasia is congenital, while atrophy occurs after full development.</p> Signup and view all the answers

    Which of the following terms refers to incomplete or underdevelopment of an organ?

    <p>Hypoplasia</p> Signup and view all the answers

    A condition characterized by the complete lack of development of an organ is known as:

    <p>Aplasia</p> Signup and view all the answers

    What does the term "hypotrophy" or "abiotrophy" describe?

    <p>Progressive loss of tissue vitality and function</p> Signup and view all the answers

    Study Notes

    Cell Adaptation

    • Cell adaptation occurs when cellular homeostasis is disrupted by stress or disease.
    • Cells adapt to stress; failure to adapt leads to cellular injury.
    • Adaptation preserves cellular viability and function.
    • Adaptation is not an irreversible change.
    • Adaptation can be physiological or pathological.

    Types of Cellular Adaptation

    • Atrophy: Decreased cell size and/or number, along with decreased metabolic activity after normal growth has been reached. Cells are not dead. This is characterized by a decrease in protein synthesis and an increase in protein degradation.
      • Causes: Decreased workload, denervation, reduced blood supply or oxygen, inadequate nutrition, loss of endocrine stimulation, and aging (senescence).
      • Examples: Muscle disuse (e.g., limb in a cast), sedentary lifestyle, atrophy of the adrenal cortex due to reduced ACTH stimulation (steroid therapy), atrophy in tissues adjacent to tumors due to pressure and compromised blood supply, and physiological atrophy (e.g., non-lactating mammary gland, postpartum uterus).
    • Hypertrophy: Increased cell size.
    • Hyperplasia: Increased cell number.
    • Dysplasia: Disordered cell growth and maturation.
    • Metaplasia: Replacement of one cell type by another.

    Homeostasis

    • Homeostasis is the tendency toward stability in the normal state of an organism.

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    Description

    Explore the concepts of cellular adaptation and homeostasis. This quiz covers the types of cell adaptation, including atrophy, hypertrophy, hyperplasia, dysplasia, and metaplasia, as well as the importance of maintaining cellular viability and function. Test your understanding of how cells respond to stress and disease.

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