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Lecture 1.1c - Cell injury and cell death 1

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6 Questions

What is the primary characteristic that distinguishes gangrene from other types of necrosis?

Visible to the naked eye

What type of necrosis is associated with dry gangrene?

Coagulative necrosis

What is the term used to describe an area of necrotic tissue resulting from loss of arterial blood supply?

Infarction

Which type of gangrene is characterized by the production of gas by anaerobic bacteria?

Gas gangrene

What is the primary difference between wet gangrene and dry gangrene?

Presence of air exposure

Which of the following is NOT a type of gangrene?

Ischaemic gangrene

Study Notes

Gangrene, Infarction, and Infarct

  • Gangrene is a clinical term describing necrosis visible to the naked eye, not a type of necrosis itself.
  • Infarction is necrosis caused by a reduction in arterial blood flow, which can result in gangrene.
  • Infarction is also an area of necrotic tissue resulting from a loss of arterial blood supply, also known as an area of ischemic necrosis.

Types of Gangrene

  • Dry gangrene: necrosis modified by exposure to air, characterized by coagulative necrosis, resulting in blackening and desiccation of the affected area.
  • Wet gangrene: necrosis modified by infection with a mixed bacterial culture, characterized by liquefactive necrosis, resulting in a foul-smelling, oozing affect.
  • Gas gangrene: a type of wet gangrene where the infection is with anaerobic bacteria that produce gas.

Understand the differences between gangrene and infarction, including their causes, effects, and characteristics in the context of necrosis and tissue damage.

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