18 Questions
What is the consequence of severe injury?
A pathologic process
Which type of necrosis is most commonly seen in hypoxic death of all tissues except the brain?
Coagulative necrosis
What is the characteristic of affected cells in coagulative necrosis?
Acidophilic, opaque mass with loss of nucleus
What is the result of microbial stimulation in liquefactive necrosis?
Accumulation of leucocytes and liberation of enzymes
What is the gross morphology of affected area in liquefactive necrosis?
Affected area is soft, liquid, viscous mass
What is the difference between coagulative necrosis and liquefactive necrosis?
Coagulative necrosis affects all tissues except brain, while liquefactive necrosis affects brain tissue
What is the appearance of the affected area in caseous necrosis?
Soft, friable white cheesy material
What is the cause of fat necrosis in acute haemorrhagic pancreatitis?
Release of activated pancreatic lipases
What type of necrosis is characterized by complete destruction of cells and is amorphous acidophilic fluid?
Gangrenous necrosis
What is the result of the combination of fatty acids with calcium in fat necrosis?
Visible chalky white areas
What is the predominant type of necrosis in dry gangrene?
Coagulative necrosis
What is the cause of liquefactive necrosis in gangrenous necrosis?
Bacteria and the attracted leucocytes
What is the characteristic histological feature of fibrinoid necrosis?
Bright pink and amorphous appearances in H&E stains
What is the primary cause of dry gangrene?
Arterial occlusion
What is the characteristic difference in the distribution of dry and wet gangrene?
Dry gangrene affects only limbs, while wet gangrene affects limbs and bowel
What is the characteristic gross appearance of wet gangrene?
Moist, soft, and swollen
What is the primary difference in the presence of bacteria between dry and wet gangrene?
Bacteria are present in wet gangrene but absent in dry gangrene
What is the characteristic feature of traumatic fat necrosis?
Due to trauma to superficial adipose tissue
Assess your understanding of necrosis and gangrene, including their definitions, types, and clinical examples. This quiz covers coagulative, liquefactive, caseous, fat, and fibrinoid necrosis, as well as dry and wet gangrene.
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