Pathology findings in Acute Hepatitis C
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Questions and Answers

What is the main pathological feature observed in Hepatitis?

  • Bile plugs in canalliculi under microscope
  • Cytolysis or apoptosis (Councilman bodies) (correct)
  • Hepatocyte proliferation
  • Fatty change in HCV - hydropic degeneration

Which feature is indicative of hepatocyte damage in liver pathology?

  • Bridging necrosis (correct)
  • Intracellular debris in Kupffer cells
  • Mononuclear cells in sinusoids
  • Severe cases: porto-portal, central-central, porto-central accumulation of fat-like indicate bridging necrosis

What is a common histological finding in Cholestasis?

  • Hepatocyte proliferation
  • Round eosinophilic structures (correct)
  • Mononuclear cells in sinusoids
  • Focal necrosis

Which term refers to the phenomenon of bile plugs being present in canalliculi under a microscope?

<p>Cholestasis (A)</p> Signup and view all the answers

What is a characteristic feature of Akut Hepatit Patolojisi (Acute Hepatitis Pathology)?

<p>Periportal necrosis (D)</p> Signup and view all the answers

What type of inflammatory cells are mostly seen in the small necrotic foci around apoptotic cells in Hepatitis?

<p>Macrophages and lymphocytes (B)</p> Signup and view all the answers

What is a common clinical finding in patients with chronic viral hepatitis?

<p>Spider angioma and hepatomegaly (D)</p> Signup and view all the answers

Which histological feature is typically seen in acute viral hepatitis but not in chronic viral hepatitis?

<p>Bridging necrosis (A)</p> Signup and view all the answers

What is the significance of 'Ground glass' appearance in chronic HCV hepatitis?

<p>It represents active viral replication (A)</p> Signup and view all the answers

Which symptom is NOT commonly associated with chronic viral hepatitis?

<p>Joint pain (A)</p> Signup and view all the answers

What is a distinguishing feature of pure cholestatic hepatitis as opposed to viral hepatitis?

<p>Prominent bile duct changes (B)</p> Signup and view all the answers

In chronic HBV hepatitis, what is the significance of the 'ground glass' appearance observed in the cytoplasm?

<p>It corresponds to active HBV replication (A)</p> Signup and view all the answers

Which type of hepatitis virus is usually chronic and rarely detected acutely?

<p>Hepatitis C (C)</p> Signup and view all the answers

What is the characteristic histopathological feature associated with Hepatitis C?

<p>Fatty change and lymphoid aggregates/follicles (C)</p> Signup and view all the answers

Which virus is known to cause chronic liver disease by potentially progressing to chronic hepatitis?

<p>Hepatitis B (A)</p> Signup and view all the answers

What is a histological indicator of Hepatitis B infection?

<p>Ground glass cells (D)</p> Signup and view all the answers

In the pathology of chronic hepatitis, what is observed in the early stage regarding fibrosis?

<p>Mild fibrotic expansion in portal areas (D)</p> Signup and view all the answers

Which type of hepatitis can be transmitted through blood or during birth?

<p>Hepatitis B (A)</p> Signup and view all the answers

What is the most important complication of liver biopsy?

<p>Bleeding (B)</p> Signup and view all the answers

Which type of hepatitis presents with less inflammation but more hepatocyte deaths compared to chronic hepatitis?

<p>Acute hepatitis (C)</p> Signup and view all the answers

What is the first finding in hepatocytes in the process of necrosis?

<p>Hidrotic degeneration (A)</p> Signup and view all the answers

Which type of necrosis is characterized by necrosis in pericentral hepatocytes in severe cases of liver pathology?

<p>E Bridging necrosis (D)</p> Signup and view all the answers

What is the defining characteristic of fulminant hepatitis?

<p>Massive hepatic necrosis (C)</p> Signup and view all the answers

What type of inflammation is minimal or absent in acute hepatitis?

<p>&quot;Portal inflammation&quot; (D)</p> Signup and view all the answers

In chronic hepatitis, what happens to the limiting plates between the portal area and hepatocytes?

<p>&quot;Interface hepatitis&quot; (B)</p> Signup and view all the answers

Which type of hepatitis shows only mild spotty necrosis in chronic cases?

<p>&quot;Chronic inactive hepatitis&quot; (B)</p> Signup and view all the answers

"Councilman body" is associated with which pathology in liver cells?

<p>&quot;One cell necrosis&quot; (B)</p> Signup and view all the answers

"ALT and AST increase 5 times, ALP and GGT increase" in which condition?

<p>Viral hepatitis (all types) (A)</p> Signup and view all the answers

What is the main difference in the inflammatory cells involved in acute and chronic viral hepatitis?

<p>Acute viral hepatitis involves mainly T cells, while chronic viral hepatitis involves mainly B cells. (A)</p> Signup and view all the answers

Which of the following viruses requires co-infection with Hepatitis B for increased risks of fulminant hepatitis, cirrhosis, and hepatocellular carcinoma?

<p>Delta Virus (HDV) (D)</p> Signup and view all the answers

What is the most common route of transmission for Hepatitis A virus?

<p>Fecal-oral (water) (D)</p> Signup and view all the answers

Which virus has the highest probability of causing fulminant hepatitis when superinfected with Hepatitis B?

<p>Delta Virus (HDV) (C)</p> Signup and view all the answers

What is the main mode of transmission for Hepatitis C Virus?

<p>Parenteral transmission (D)</p> Signup and view all the answers

In which type of infection does Hepatitis E Virus commonly result?

<p>Only acute hepatitis (C)</p> Signup and view all the answers

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