Pathology findings in Acute Hepatitis C

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What is the main pathological feature observed in Hepatitis?

Bile plugs in canalliculi under microscope

Cytolysis or apoptosis (Councilman bodies) (correct)

Hepatocyte proliferation

Fatty change in HCV - hydropic degeneration

Which feature is indicative of hepatocyte damage in liver pathology?

Bridging necrosis (correct)

Intracellular debris in Kupffer cells

Mononuclear cells in sinusoids

Severe cases: porto-portal, central-central, porto-central accumulation of fat-like indicate bridging necrosis

What is a common histological finding in Cholestasis?

Hepatocyte proliferation

Round eosinophilic structures (correct)

Mononuclear cells in sinusoids

Focal necrosis

Which term refers to the phenomenon of bile plugs being present in canalliculi under a microscope?

Cholestasis Signup and view all the answers

What is a characteristic feature of Akut Hepatit Patolojisi (Acute Hepatitis Pathology)?

Periportal necrosis Signup and view all the answers

What type of inflammatory cells are mostly seen in the small necrotic foci around apoptotic cells in Hepatitis?

Macrophages and lymphocytes Signup and view all the answers

What is a common clinical finding in patients with chronic viral hepatitis?

Spider angioma and hepatomegaly Signup and view all the answers

Which histological feature is typically seen in acute viral hepatitis but not in chronic viral hepatitis?

Bridging necrosis Signup and view all the answers

What is the significance of 'Ground glass' appearance in chronic HCV hepatitis?

It represents active viral replication Signup and view all the answers

Which symptom is NOT commonly associated with chronic viral hepatitis?

Joint pain Signup and view all the answers

What is a distinguishing feature of pure cholestatic hepatitis as opposed to viral hepatitis?

Prominent bile duct changes Signup and view all the answers

In chronic HBV hepatitis, what is the significance of the 'ground glass' appearance observed in the cytoplasm?

It corresponds to active HBV replication Signup and view all the answers

Which type of hepatitis virus is usually chronic and rarely detected acutely?

Hepatitis C Signup and view all the answers

What is the characteristic histopathological feature associated with Hepatitis C?

Fatty change and lymphoid aggregates/follicles Signup and view all the answers

Which virus is known to cause chronic liver disease by potentially progressing to chronic hepatitis?

Hepatitis B Signup and view all the answers

What is a histological indicator of Hepatitis B infection?

Ground glass cells Signup and view all the answers

In the pathology of chronic hepatitis, what is observed in the early stage regarding fibrosis?

Mild fibrotic expansion in portal areas Signup and view all the answers

Which type of hepatitis can be transmitted through blood or during birth?

Hepatitis B Signup and view all the answers

What is the most important complication of liver biopsy?

Bleeding Signup and view all the answers

Which type of hepatitis presents with less inflammation but more hepatocyte deaths compared to chronic hepatitis?

Acute hepatitis Signup and view all the answers

What is the first finding in hepatocytes in the process of necrosis?

Hidrotic degeneration Signup and view all the answers

Which type of necrosis is characterized by necrosis in pericentral hepatocytes in severe cases of liver pathology?

E Bridging necrosis Signup and view all the answers

What is the defining characteristic of fulminant hepatitis?

Massive hepatic necrosis Signup and view all the answers

What type of inflammation is minimal or absent in acute hepatitis?

"Portal inflammation" Signup and view all the answers

In chronic hepatitis, what happens to the limiting plates between the portal area and hepatocytes?

"Interface hepatitis" Signup and view all the answers

Which type of hepatitis shows only mild spotty necrosis in chronic cases?

"Chronic inactive hepatitis" Signup and view all the answers

"Councilman body" is associated with which pathology in liver cells?

"One cell necrosis" Signup and view all the answers

"ALT and AST increase 5 times, ALP and GGT increase" in which condition?

Viral hepatitis (all types) Signup and view all the answers

What is the main difference in the inflammatory cells involved in acute and chronic viral hepatitis?

Acute viral hepatitis involves mainly T cells, while chronic viral hepatitis involves mainly B cells. Signup and view all the answers

Which of the following viruses requires co-infection with Hepatitis B for increased risks of fulminant hepatitis, cirrhosis, and hepatocellular carcinoma?

Delta Virus (HDV) Signup and view all the answers

What is the most common route of transmission for Hepatitis A virus?

Fecal-oral (water) Signup and view all the answers