24 Questions
Which diameter is defined as the diameter of a sphere having the same settling velocity as the particle of interest?
Stokes’ diameter
What is the term for particles of the same size?
Monodispersed
Which method is used to find the diameter of irregular particles?
Aerodynamic diameter
What is Martin’s diameter?
The length of a line that divides a particle into two equal halves
What is a weakness of optical microscopy compared to scanning electron microscopy (SEM)?
Limited resolution (0.2-0.5μm)
What is a strength of sieving as a quantitative analysis method?
Simple, quick, and inexpensive
What is a weakness of the Andreasen apparatus?
Lower limit around 1 μm
What is a strength of scanning electron microscopy (SEM) compared to optical microscopy?
High resolution (1-20 nm)
Which diameter is defined as the length of a line that divides a particle into two equal halves?
Martin’s diameter
What is the term for particles of different sizes?
Polydisperse
Which method of particle sizing relates all diameters and is used to find the diameter of irregular particles?
Aerodynamic diameter
What is the diameter of a sphere having the same settling velocity as the particle of interest, used to find the size of particles?
Stokes’ diameter
What is a limitation of optical microscopy for quantitative analysis?
Limited resolution of 0.2-0.5μm
What is a weakness shared by both scanning electron microscopy (SEM) and optical microscopy?
Inability to distinguish overlapping particles or agglomerates
What is a limitation of sieving as a quantitative analysis method?
Lower size limit of 25-50μm
What is a strength of the Andreasen apparatus for particle analysis?
Direct measurement of stokes diameter
What is the term for particles of different sizes?
Polydisperse
What is Martin’s diameter?
Length of a line that divides particle into leave into halves
What is the diameter of a sphere having the same settling velocity as the particle of interest, used to find the size of particles?
Stokes’ diameter
What is a strength of scanning electron microscopy (SEM) compared to optical microscopy?
Higher resolution for smaller particles
What is a weakness shared by both scanning electron microscopy (SEM) and optical microscopy?
Low resolution
What is a strength of sieving as a quantitative analysis method?
Wide particle size range
What is a limitation of the Andreasen apparatus?
Lower limit around 1μm
What is a strength of optical microscopy for qualitative analysis?
Ability to visualize and quickly analyze samples
Test your knowledge of micrometrics and the importance of particle size in therapeutic considerations with this quiz. Explore the impact of particle size on flowability, mixing, sedimentation, creaming, skin feel, stability, and lung deposition in various pharmaceutical formulations. Learn about monodispersed and polydisperse particles and their implications for drug delivery.
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