Drug Absorption and Particle Size Quiz
5 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

How does particle size reduction affect the effective surface area of the drug?

  • It decreases the effective surface area
  • It slightly increases the effective surface area
  • It increases the effective surface area enormously (correct)
  • It has no effect on the effective surface area

    • What is the impact of micronized particle size on the absorption of low aqueous solubility drugs?

  • It only affects specific drugs
  • It decreases absorption rates
  • It increases absorption rates (correct)
  • It has no effect on absorption rates

    • Why might a disintegrant be added to the formulation of poorly soluble drugs?

  • To decrease the water penetration into the particles
  • To ensure rapid disintegration of the tablet and release of the particles (correct)
  • To reduce the dissolution rates
  • To limit the total surface area of the particles

    • What is a limitation of extensive particle size reduction for poorly soluble, hydrophobic drugs?

    <p>It increases the tendency of particles to aggregate in aqueous GIT fluids</p> Signup and view all the answers

    Why might increased rate of dissolution be undesirable for certain drugs like penicillin G and erythromycin?

    <p>It results in increased drug degradation</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser