Parkinson's Disease Pathology and Clinical Features
10 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What has been associated with a 50% reduced risk of developing PD?

  • Environmental toxins
  • Genetic mutations in genes like SNCA, PRKN, LRRK2, and PINK1
  • Vagotomy (correct)
  • Dopamine replacement therapy using levodopa and dopamine agonists

Which neurotransmitter is thought to underlie many of the motor symptoms seen in PD patients?

  • Acetylcholine
  • Serotonin
  • Dopamine (correct)
  • Norepinephrine

What has been found to increase microglial TLR4 expression and markers of activation in PD?

  • Dopamine replacement therapy
  • Vagotomy
  • Environmental toxins
  • Alpha-synuclein (correct)

Which area of research focuses on deep brain stimulation, neurotrophic factors, and stem cell transplantation for PD?

<p>Emerging and experimental therapies (A)</p> Signup and view all the answers

Where are Lewy bodies known to first occur in relation to PD?

<p>Vagal nerve (A)</p> Signup and view all the answers

What is the key pathological feature of Parkinson's disease involving the accumulation of Lewy bodies?

<p>Increased reactive microglia (C)</p> Signup and view all the answers

Which area of the brain experiences the initial loss of dopamine neurons in Parkinson's disease?

<p>Substantia nigra pars compacta (A)</p> Signup and view all the answers

What non-motor symptom is associated with Parkinson's disease?

<p>Dementia (B)</p> Signup and view all the answers

Which area experiences a loss of dopamine innervation due to the loss of dopamine-producing neurons in Parkinson's disease?

<p>Striatum (D)</p> Signup and view all the answers

How is Parkinson's disease typically diagnosed?

<p>Neuroimaging techniques or immunohistochemistry after death (A)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser