Podcast
Questions and Answers
Which characteristic is not associated with the pathology of Parkinson's Disease?
Which characteristic is not associated with the pathology of Parkinson's Disease?
- Increased dopamine innervation in the cortex (correct)
- Loss of neuromelanin
- Accumulation of Lewy bodies containing alpha-synuclein
- Death of astrocytes
What is the main role of the gut and vagus nerve in Parkinson's Disease?
What is the main role of the gut and vagus nerve in Parkinson's Disease?
- Trigger Lewy body accumulation in the substantia nigra pars compacta
- Contribute to the development of non-motor symptoms (correct)
- Directly produce dopamine for replacement therapy
- Prevent the loss of dopamine-producing neurons in the midbrain
Which gene mutation is NOT associated with familial Parkinson's Disease?
Which gene mutation is NOT associated with familial Parkinson's Disease?
- LRRK2
- APP (correct)
- SNCA
- PRKN
What is the potential impact of vagotomy on Parkinson's Disease development?
What is the potential impact of vagotomy on Parkinson's Disease development?
Which treatment is NOT part of the non-dopaminergic agents for motor/non-motor symptoms in Parkinson's Disease?
Which treatment is NOT part of the non-dopaminergic agents for motor/non-motor symptoms in Parkinson's Disease?
What is considered an early cause rather than a late consequence of Parkinson's Disease?
What is considered an early cause rather than a late consequence of Parkinson's Disease?
Which receptor family excites neurons in the context of dopamine neurotransmission?
Which receptor family excites neurons in the context of dopamine neurotransmission?
What is the primary abnormal motor feature associated with Parkinson's Disease?
What is the primary abnormal motor feature associated with Parkinson's Disease?
In which region does the progressive loss of dopamine producing neurons occur in Parkinson's Disease?
In which region does the progressive loss of dopamine producing neurons occur in Parkinson's Disease?
Which neuroinflammatory process is increased in a mouse model of Parkinson's Disease?
Which neuroinflammatory process is increased in a mouse model of Parkinson's Disease?
