Parkinson's Disease Overview

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10 Questions

What part of the brain is affected by the degeneration of nerve cells in Parkinson's disease?

Substantia nigra

What important chemical is not produced in sufficient quantities due to the degeneration of nerve cells in Parkinson's disease?

Dopamine

At what percentage loss of dopamine-producing cells in the substantia nigra do symptoms of Parkinson's typically develop?

80 percent

What are the hallmark symptoms of Parkinson's disease?

Tremor, rigidity, slowness of movement, impaired balance and coordination

How does the lack of dopamine affect the coordination of nerve and muscle cells involved in movement?

Disrupts the delicate balance with other neurotransmitters

Parkinson’s disease is a progressive disorder caused by degeneration of nerve cells in the part of the brain called the substantia nigra, which controls ______.

movement

Studies have shown that symptoms of Parkinson's develop in patients with an 80 percent or greater loss of ______-producing cells in the substantia nigra.

dopamine

Normally, dopamine operates in a delicate balance with other neurotransmitters to help coordinate the millions of nerve and muscle cells involved in ______.

movement

Without enough dopamine, the balance is disrupted, resulting in tremor, rigidity, slowness of movement, and impaired balance and ______ – the hallmark symptoms of Parkinson's.

coordination

The hallmark symptoms of Parkinson's include tremor, rigidity, slowness of movement, and impaired balance and ______.

coordination

Learn about the progressive disorder caused by degeneration of nerve cells in the substantia nigra leading to a loss of dopamine production. Explore the symptoms and impact of Parkinson's disease on movement control.

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