Podcast
Questions and Answers
Which time of day is plasma PTH levels the highest?
Which time of day is plasma PTH levels the highest?
- In the early hours of the morning (correct)
- At noon
- In the evening
- In the afternoon
What is the net effect of the activation by intact PTH at the renal tubule?
What is the net effect of the activation by intact PTH at the renal tubule?
- Increases the reabsorption of phosphate and bicarbonate
- Lowers plasma [Ca2+]
- Increases GFR (correct)
- Decreases the reabsorption of calcium and magnesium
Where are the high levels of the parathyroid hormone 1 receptor located?
Where are the high levels of the parathyroid hormone 1 receptor located?
- Central nervous system
- Liver
- Bone (correct)
- Pancreas
Which signaling pathway is activated upon binding of PTH to its receptor?
Which signaling pathway is activated upon binding of PTH to its receptor?
What action does PTH have on the distal tubule in the kidney?
What action does PTH have on the distal tubule in the kidney?
What is the rapid action associated with PTH in bone?
What is the rapid action associated with PTH in bone?
What inhibits the activity of 1α-hydroxylase?
What inhibits the activity of 1α-hydroxylase?
Which enzyme catalyzes the hydroxylation of 25-HCC to 24:25-DHCC?
Which enzyme catalyzes the hydroxylation of 25-HCC to 24:25-DHCC?
What promotes the intestinal reabsorption of calcium?
What promotes the intestinal reabsorption of calcium?
Which protein is released into the bloodstream during bone formation?
Which protein is released into the bloodstream during bone formation?
What can be used as a marker of bone formation and turnover?
What can be used as a marker of bone formation and turnover?
What stimulates the mature osteoclasts leading to bone resorption?
What stimulates the mature osteoclasts leading to bone resorption?
What is the most common single presenting complaint in Primary Hyperparathyroidism?
What is the most common single presenting complaint in Primary Hyperparathyroidism?
What is the most serious complication of Primary Hyperparathyroidism?
What is the most serious complication of Primary Hyperparathyroidism?
Which of the following is NOT a characteristic feature of Secondary Hyperparathyroidism?
Which of the following is NOT a characteristic feature of Secondary Hyperparathyroidism?
What causes hypercalcemia in Primary Hyperparathyroidism?
What causes hypercalcemia in Primary Hyperparathyroidism?
In Primary Hyperparathyroidism, what is responsible for the autonomous production of PTH?
In Primary Hyperparathyroidism, what is responsible for the autonomous production of PTH?
Which organ is most commonly affected in Primary Hyperparathyroidism?
Which organ is most commonly affected in Primary Hyperparathyroidism?
What is the primary target cell for calcitonin?
What is the primary target cell for calcitonin?
What is the effect of calcitonin on osteoblastic activity?
What is the effect of calcitonin on osteoblastic activity?
During which periods is plasma [calcitonin] elevated?
During which periods is plasma [calcitonin] elevated?
What is the mechanism by which calcitonin reduces plasma [Ca2+]?
What is the mechanism by which calcitonin reduces plasma [Ca2+]?
What is the effect of calcitonin on PTH activity?
What is the effect of calcitonin on PTH activity?
How does calcitonin protect against calcium loss from the skeleton?
How does calcitonin protect against calcium loss from the skeleton?
What is the effect of PTH on osteoclasts?
What is the effect of PTH on osteoclasts?
What is the role of 25-hydroxylase in vitamin D metabolism?
What is the role of 25-hydroxylase in vitamin D metabolism?
What is the location of the 1α-hydroxylase enzyme?
What is the location of the 1α-hydroxylase enzyme?
What is the result of PTH stimulating osteoblast activity?
What is the result of PTH stimulating osteoblast activity?
What is the role of vitamin D-binding protein?
What is the role of vitamin D-binding protein?
What is the effect of PTH on plasma Ca2+ and phosphate levels?
What is the effect of PTH on plasma Ca2+ and phosphate levels?
