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Pain Perception Theory and Neurotransmitters

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Pain Perception Theory and Neurotransmitters

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Questions and Answers

What is the role of prostaglandins in pain perception?

Close nerve 'gates' to painful input

Inhibit the transmission of pain signals

Enhance pain receptor sensitivity (correct)

Decrease pain sensitivity

Which chemical amplifies the pain signal and is found in C fibers?

Enkephalins

Endorphins

Prostaglandins

Substance P (correct)

What type of fibers are selectively stimulated with electrodes in PhysioRX TENS to lessen pain?

C fibers

Nociceptive fibers

Nerve 'gates'

Non-nociceptive fibers (correct)

According to the GATE CONTROL THEORY, how is pain modulated?

By closing nerve 'gates' with non-painful input Signup and view all the answers

What is a characteristic of neuropathic pain according to the text?

Persistent neural changes and increased sensitivity Signup and view all the answers

What does peripheral sensitization involve?

Lowering the threshold and increasing excitability of nerve terminals Signup and view all the answers

What is a factor that can activate TRPV1 exogenously?

Low temperature Signup and view all the answers

Which endogenous substance acts as a TRPV1 activator?

Anandamide Signup and view all the answers

What is a characteristic of long exposure to capsaicin on TRPV1 sensitization?

Desensitization Signup and view all the answers

Which type of pain occurs due to ectopic activity post-injury?

Spontaneous pain Signup and view all the answers

What is a mechanism involved in central sensitization?

Loss of inhibition from the dorsal horn Signup and view all the answers

Which neurotransmitter receptor is NOT a major player in central sensitization?

mGluR receptor Signup and view all the answers