Pain Perception Theory and Neurotransmitters
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Questions and Answers

What is the role of prostaglandins in pain perception?

  • Close nerve 'gates' to painful input
  • Inhibit the transmission of pain signals
  • Enhance pain receptor sensitivity (correct)
  • Decrease pain sensitivity

Which chemical amplifies the pain signal and is found in C fibers?

  • Enkephalins
  • Endorphins
  • Prostaglandins
  • Substance P (correct)

What type of fibers are selectively stimulated with electrodes in PhysioRX TENS to lessen pain?

  • C fibers
  • Nociceptive fibers
  • Nerve 'gates'
  • Non-nociceptive fibers (correct)

According to the GATE CONTROL THEORY, how is pain modulated?

<p>By closing nerve 'gates' with non-painful input (B)</p> Signup and view all the answers

What is a characteristic of neuropathic pain according to the text?

<p>Persistent neural changes and increased sensitivity (D)</p> Signup and view all the answers

What does peripheral sensitization involve?

<p>Lowering the threshold and increasing excitability of nerve terminals (A)</p> Signup and view all the answers

What is a factor that can activate TRPV1 exogenously?

<p>Low temperature (D)</p> Signup and view all the answers

Which endogenous substance acts as a TRPV1 activator?

<p>Anandamide (C)</p> Signup and view all the answers

What is a characteristic of long exposure to capsaicin on TRPV1 sensitization?

<p>Desensitization (C)</p> Signup and view all the answers

Which type of pain occurs due to ectopic activity post-injury?

<p>Spontaneous pain (B)</p> Signup and view all the answers

What is a mechanism involved in central sensitization?

<p>Loss of inhibition from the dorsal horn (A)</p> Signup and view all the answers

Which neurotransmitter receptor is NOT a major player in central sensitization?

<p>mGluR receptor (A)</p> Signup and view all the answers

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