Pain Management and Side Effects of NSAIDs and Opioids

Explore the management of pain using non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, fenoprofen, naproxen, and opioids. Learn about the side effects associated with these medications including abdominal or lower back pain, jaundice, hemoglobinuria, anemia, hepatic necrosis, and nephrotoxicity.

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Questions and Answers

What is the primary mechanism of action of fentanyl compared to morphine?

Fentanyl has a faster onset and shorter duration of pain relief when administered by injection.

Why is meperidine (pethidine) used less often than other opioid analgesics?

Meperidine is associated with a higher incidence of side effects compared to other opioids.

What is the primary use of dextropropoxyphene?

Dextropropoxyphene is a weak opioid that is usually combined with acetaminophen for the treatment of mild to moderate pain.

Which of the following is an opioid antagonist?

Naloxone Signup and view all the answers

Which of the following is considered a non-narcotic analgesic?

Tramadol Signup and view all the answers

Which of the following is a non-narcotic analgesic with marked anti-inflammatory activity?

Ibuprofen Signup and view all the answers

What is the primary mechanism of action for narcotic analgesics in the spinal cord?

Blocking pain messages to the brain Signup and view all the answers

Which of the following is a non-narcotic analgesic with mild to moderate anti-inflammatory activity?

Naproxen Signup and view all the answers

Which of the following narcotic analgesics is often referred to as the 'gold standard' among opioids?

Morphine Signup and view all the answers

Which of the following is a semisynthetic opioid derived from morphine in the 1920s?

Hydromorphone Signup and view all the answers

What is the primary mechanism of action for narcotic analgesics in the brain?

Changing the interpretation of pain messages Signup and view all the answers

What is the effect of prostaglandin binding to smooth muscle tissues in blood vessels?

Vasodilation Signup and view all the answers

Which eicosanoid increases platelet aggregability and is important for the clotting mechanism?

Thromboxane Signup and view all the answers

What is a characteristic of non-narcotic analgesics?

Abuse potential Signup and view all the answers

Which type of analgesic usually requires drug regulations like DD (Dangerous Drug) or Rx (Prescription)?

Narcotic analgesics Signup and view all the answers

What is the main reason non-narcotic analgesics do not cause physical dependence?

They act on different receptors than narcotics Signup and view all the answers

Which pharmacologic action is associated with non-narcotic analgesics?

Analgesia Signup and view all the answers

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