Escalation of Potency in Pain Management with NSAIDs and Opioids

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15 Questions

What is the current recommendation for meeting nutritional needs in patients with pancreatitis?

Utilize the enteral route whenever possible

What is a potential benefit of escalating from low potency to higher potency of NSAIDs alone or in combination with opioids for pain management?

Improved pain management

When should enteral feedings be initiated in the course of acute pancreatitis?

Early in the course of the disease

Why should NSAIDs be avoided or used with caution in patients at risk for bleeding?

To lower the potential for bleeding

What is the role of parenteral nutrition in severe acute pancreatitis?

It is used when enteral nutrition cannot be tolerated

What common problems can be aggravated with the use of high-dose opioids in early acute pancreatitis?

GI paralysis and ileus

What symptom may nasogastric suction help relieve in acute pancreatitis?

Nausea and vomiting

Why is it important to follow guidelines for acute pain management in the perioperative setting?

Until evidence-based recommendations are developed

Why is the routine use of nasogastric tubes not supported for patients with acute pancreatitis?

To limit pancreatic secretion

What is a necessary correction in intensive care for patients with acute pancreatitis to prevent acute kidney injury?

Correction of fluid and blood loss

What type of therapy is discouraged in the literature but is still common for hospitalized patients?

Acid-suppressive therapy

Which type of medication inhibits gastric acid secretion by decreasing pancreatic activity?

Histamine-2 (H2) antagonists

What is the recommended approach to pain management in patients with pancreatitis?

Utilizing opioids and assessing effectiveness

Which medication may be used for patients who do not tolerate Histamine-2 (H2) antagonists or for whom this therapy is ineffective?

Proton pump inhibitors

What approach provides a pragmatic way to manage pain in patients with pancreatitis?

Implementing the World Health Organization (WHO) analgesia ladder

Learn about the stepwise escalation of potency from low to high in the management of pain using nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids, as well as the potential benefits in lowering opioid dependency. Understand the considerations and precautions in using NSAIDs in patients.

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