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Questions and Answers
What is the primary mechanism of action of NSAIDs?
Which medication is specifically used to treat period pain (menorrhagia)?
What type of pain is associated with damage to nerve fibers?
Which medication is a weak μ-opioid receptor agonist?
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What is the primary site of action for Paracetamol?
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What type of pain is associated with the use of NSAIDs?
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Which medication is characterized by being contraindicated in asthmatics and those with gastric problems?
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What is the site of action for medications such as Amitriptyline and Gabapentin?
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What is the primary mechanism of action of medications such as Ibuprofen, Naproxen, and Diclofenac?
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Which medication is used in combination with Codeine to form Co-codamol?
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What is the primary site of action for NSAIDs?
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Which type of pain is specifically targeted by medications like Amitriptyline and Pregabalin?
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What is the primary mechanism of action of medications like Paracetamol?
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Which medication is a combination of Codeine and another analgesic?
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What is the site of action for medications like Morphine?
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Study Notes
The Analgesic Ladder
- The analgesic ladder mirrors the pain pathway, with NSAIDs being the first step in pain management
- NSAIDs work at the site of injury or painful stimulus, targeting inflammatory pain
NSAIDs
- Examples of NSAIDs include ibuprofen, Naproxen, and Diclofenac
- NSAIDs inhibit the production of prostaglandins through Cox inhibitors
- Contraindications for NSAIDs include asthmatics and individuals with gastric problems
- Specific NSAIDs can be used for certain conditions, such as mefenamic acid for period pain (menorrhagia)
Analgesia and Descending Control
- Analgesia is achieved through descending control mechanisms
- Examples of analgesics in this category include Paracetamol, Codeine-based co-codamol, and Tramadol
- Tramadol is a very weak μ-opioid receptor agonist
Neuropathic Pain Management
- Neuropathic pain is managed through spinal (dorsal horn neurons) mechanisms
- Examples of medications used to manage neuropathic pain include Amitriptyline, gabapentin, and Pregabalin
The Analgesic Ladder
- The analgesic ladder mirrors the pain pathway, with NSAIDs being the first step in pain management
- NSAIDs work at the site of injury or painful stimulus, targeting inflammatory pain
NSAIDs
- Examples of NSAIDs include ibuprofen, Naproxen, and Diclofenac
- NSAIDs inhibit the production of prostaglandins through Cox inhibitors
- Contraindications for NSAIDs include asthmatics and individuals with gastric problems
- Specific NSAIDs can be used for certain conditions, such as mefenamic acid for period pain (menorrhagia)
Analgesia and Descending Control
- Analgesia is achieved through descending control mechanisms
- Examples of analgesics in this category include Paracetamol, Codeine-based co-codamol, and Tramadol
- Tramadol is a very weak μ-opioid receptor agonist
Neuropathic Pain Management
- Neuropathic pain is managed through spinal (dorsal horn neurons) mechanisms
- Examples of medications used to manage neuropathic pain include Amitriptyline, gabapentin, and Pregabalin
The Analgesic Ladder
- The analgesic ladder mirrors the pain pathway, with NSAIDs being the first step in pain management
- NSAIDs work at the site of injury or painful stimulus, targeting inflammatory pain
NSAIDs
- Examples of NSAIDs include ibuprofen, Naproxen, and Diclofenac
- NSAIDs inhibit the production of prostaglandins through Cox inhibitors
- Contraindications for NSAIDs include asthmatics and individuals with gastric problems
- Specific NSAIDs can be used for certain conditions, such as mefenamic acid for period pain (menorrhagia)
Analgesia and Descending Control
- Analgesia is achieved through descending control mechanisms
- Examples of analgesics in this category include Paracetamol, Codeine-based co-codamol, and Tramadol
- Tramadol is a very weak μ-opioid receptor agonist
Neuropathic Pain Management
- Neuropathic pain is managed through spinal (dorsal horn neurons) mechanisms
- Examples of medications used to manage neuropathic pain include Amitriptyline, gabapentin, and Pregabalin
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Description
Explore the analgesic ladder, which mirrors the pain pathway, and learn about the different types of medications used to manage pain, including NSAIDs, Paracetamol, and opioids.
