14 Questions
Oxidative stress is caused by an excess of antioxidants within the cell.
False
ROS are only produced as by-products of mitochondrial respiration.
False
The biological system has no mechanisms to maintain the oxidative balance.
False
NOX1 is not a membrane-bound enzyme complex
False
CYP450 proteins are not involved in Phase I metabolism of xenobiotics
False
Peroxisomes primarily play a role in carbohydrate metabolism
False
NP-induced ROS cannot cause genetic damage
False
β-carotene is a strong antioxidant.
False
Ascorbic acid is a lipid-soluble vitamin.
False
The induction of oxidative stress by NPs can only lead to negative health outcomes.
False
Oxidative stress is not associated with aging, cancer, vascular disease, neurodegeneration, diabetes or inflammation.
False
P53 is a tumor suppressor that plays a role in the link between oxidative stress and aging.
True
During low levels of oxidative stress, p53 promotes the production of oxidants which leads to cell death.
False
SOD is an enzymatic system that converts O2− to H2O2 and has three isoforms in humans that are found in different subcellular locations.
True
Test your knowledge on the physiological consequences of oxidative stress, including its association with aging, cancer, vascular disease, neurodegeneration, diabetes, and inflammation. Learn about the role of oxidative DNA, protein, and lipid damage, as well as the potential link between oxidative stress and aging through the tumor suppressor p53. Take the quiz to see how much you know about this important topic.
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