Oxidative Stress and Physiological Consequences Quiz

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Which of the following is a source of reactive oxygen species (ROS)?

Antioxidants

Glutathione peroxidase

Catalase

Mitochondrial respiration (correct)

Which of the following is a definition of prooxidants?

Chemicals that promote the production of antioxidants

Chemicals that neutralize ROS

Chemicals that induce oxidative stress (correct)

Chemicals that inhibit the antioxidant system

What are some examples of antioxidants found in the biological system?

ONOO-, H2O2, neutrophil

SOD, catalase, GPx, vitamins (correct)

SOD, hydroxyl radical, NO

ROS, catalase, GPx

What is the primary source of ROS in the vasculature?

NADPH oxidases Signup and view all the answers

Which organelle contains numerous enzymes that help to catalyze redox reactions, primarily in the role of lipid metabolism?

Peroxisomes Signup and view all the answers

Which of the following can cause oxidative stress at the cellular level?

All of the above Signup and view all the answers

What is the biochemical effect of oxidative stress?

Both A and B Signup and view all the answers

Which of the following vitamins has the ability to react with various ROS and free radical species?

Vitamin C Signup and view all the answers

Which form of Vitamin E is the most biologically active?

Alpha-tocopherol Signup and view all the answers

What is the mechanism by which α-tocopherol reduces free radicals?

It has a hydroxyl group that can react with unpaired electrons from free radicals Signup and view all the answers

What is the role of p53 in response to oxidative stress?

p53 promotes antioxidative activity at low levels of oxidative stress and increases production of oxidants at high levels of oxidative stress Signup and view all the answers

What is the function of SOD in response to oxidative stress?

SOD converts O2− to H2O2 Signup and view all the answers

What is the role of catalase in response to oxidative stress?

Catalase converts H2O2 to water and oxygen Signup and view all the answers

What is the function of ferritin and ceruloplasmin in response to oxidative stress?

Ferritin and ceruloplasmin scavenge free metal ions and prevent them from eliciting redox reaction Signup and view all the answers

Oxidative Stress and Physiological Consequences Quiz

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