Oxidative Stress and Physiological Consequences Quiz
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Questions and Answers

Which of the following is a source of reactive oxygen species (ROS)?

  • Antioxidants
  • Glutathione peroxidase
  • Catalase
  • Mitochondrial respiration (correct)

    • Which of the following is a definition of prooxidants?

  • Chemicals that promote the production of antioxidants
  • Chemicals that neutralize ROS
  • Chemicals that induce oxidative stress (correct)
  • Chemicals that inhibit the antioxidant system

    • What are some examples of antioxidants found in the biological system?

  • ONOO-, H2O2, neutrophil
  • SOD, catalase, GPx, vitamins (correct)
  • SOD, hydroxyl radical, NO
  • ROS, catalase, GPx

    • What is the primary source of ROS in the vasculature?

    <p>NADPH oxidases</p> Signup and view all the answers

    Which organelle contains numerous enzymes that help to catalyze redox reactions, primarily in the role of lipid metabolism?

    <p>Peroxisomes</p> Signup and view all the answers

    Which of the following can cause oxidative stress at the cellular level?

    <p>All of the above</p> Signup and view all the answers

    What is the biochemical effect of oxidative stress?

    <p>Both A and B</p> Signup and view all the answers

    Which of the following vitamins has the ability to react with various ROS and free radical species?

    <p>Vitamin C</p> Signup and view all the answers

    Which form of Vitamin E is the most biologically active?

    <p>Alpha-tocopherol</p> Signup and view all the answers

    What is the mechanism by which α-tocopherol reduces free radicals?

    <p>It has a hydroxyl group that can react with unpaired electrons from free radicals</p> Signup and view all the answers

    What is the role of p53 in response to oxidative stress?

    <p>p53 promotes antioxidative activity at low levels of oxidative stress and increases production of oxidants at high levels of oxidative stress</p> Signup and view all the answers

    What is the function of SOD in response to oxidative stress?

    <p>SOD converts O2− to H2O2</p> Signup and view all the answers

    What is the role of catalase in response to oxidative stress?

    <p>Catalase converts H2O2 to water and oxygen</p> Signup and view all the answers

    What is the function of ferritin and ceruloplasmin in response to oxidative stress?

    <p>Ferritin and ceruloplasmin scavenge free metal ions and prevent them from eliciting redox reaction</p> Signup and view all the answers

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