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Questions and Answers
What is the primary effect of prolonged shock on cellular function?
What is the primary effect of prolonged shock on cellular function?
Which type of shock is characterized by cold and clammy skin?
Which type of shock is characterized by cold and clammy skin?
What compensatory mechanisms are typical in the pre-shock stage?
What compensatory mechanisms are typical in the pre-shock stage?
What lab finding is likely to indicate metabolic acidosis during shock?
What lab finding is likely to indicate metabolic acidosis during shock?
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How does shock typically progress if left untreated?
How does shock typically progress if left untreated?
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Which intervention is NOT part of the ABCs of shock management?
Which intervention is NOT part of the ABCs of shock management?
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What is the primary cause of hypovolemic shock?
What is the primary cause of hypovolemic shock?
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What change occurs in systemic vascular resistance during distributive shock?
What change occurs in systemic vascular resistance during distributive shock?
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What is a common clinical finding in the shock state?
What is a common clinical finding in the shock state?
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What is the role of pulmonary capillary wedge pressure in assessing shock?
What is the role of pulmonary capillary wedge pressure in assessing shock?
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What is the primary goal of pRBC transfusion?
What is the primary goal of pRBC transfusion?
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What is the recommended hemoglobin level to initiate transfusion in actively bleeding patients?
What is the recommended hemoglobin level to initiate transfusion in actively bleeding patients?
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In which scenario should a higher hemoglobin threshold of Hb < 10 g/dL be considered for transfusion?
In which scenario should a higher hemoglobin threshold of Hb < 10 g/dL be considered for transfusion?
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What does a 'Type and Screen' test determine?
What does a 'Type and Screen' test determine?
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What should be done first if a patient exhibits signs of a transfusion reaction?
What should be done first if a patient exhibits signs of a transfusion reaction?
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Which complication occurs if symptoms develop 2-4 hours post transfusion?
Which complication occurs if symptoms develop 2-4 hours post transfusion?
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What is the primary use of a Swan-Ganz catheter?
What is the primary use of a Swan-Ganz catheter?
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Which of the following is NOT a sign of fatal hemolysis?
Which of the following is NOT a sign of fatal hemolysis?
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Which type of shock is characterized by warm, dry skin and decreased systemic vascular resistance?
Which type of shock is characterized by warm, dry skin and decreased systemic vascular resistance?
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What is a common treatment for severe allergic reactions during blood transfusion?
What is a common treatment for severe allergic reactions during blood transfusion?
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In cardiogenic shock, what is the effect on cardiac output?
In cardiogenic shock, what is the effect on cardiac output?
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What is a defining feature of neurogenic shock?
What is a defining feature of neurogenic shock?
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What type of blood product contains clotting factors and may be used during transfusion?
What type of blood product contains clotting factors and may be used during transfusion?
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Which electrolyte abnormality is commonly associated with blood transfusion?
Which electrolyte abnormality is commonly associated with blood transfusion?
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Which treatment is indicated for anaphylactic shock?
Which treatment is indicated for anaphylactic shock?
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What often causes obstructive shock?
What often causes obstructive shock?
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Which symptom is commonly associated with hypovolemic shock?
Which symptom is commonly associated with hypovolemic shock?
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What is the hemodynamic consequence of adrenal insufficiency in shock?
What is the hemodynamic consequence of adrenal insufficiency in shock?
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How does tension pneumothorax typically present?
How does tension pneumothorax typically present?
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Which parameter is calculated using the formula MAP = CO x TPR?
Which parameter is calculated using the formula MAP = CO x TPR?
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What is a common sign of obstructive shock?
What is a common sign of obstructive shock?
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Which of the following conditions is NOT typically classified as distributive shock?
Which of the following conditions is NOT typically classified as distributive shock?
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What is commonly noted in a cardiac echo for pericardial tamponade?
What is commonly noted in a cardiac echo for pericardial tamponade?
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What defines the wedge pressure in healthcare terms?
What defines the wedge pressure in healthcare terms?
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Study Notes
Shock Overview
- Life-threatening condition involving circulatory failure
- Decreased oxygen delivery, increased oxygen consumption, or impaired oxygen utilization leading to cell and tissue hypoxia.
- Inadequate end-organ perfusion results in cell death and organ dysfunction
Shock Classifications
- Hypovolemic Shock: Caused by fluid loss, such as from bleeding or dehydration.
- Cardiogenic Shock: Caused by heart failure, resulting in reduced blood flow.
- Obstructive Shock: Caused by obstruction of blood flow, such as a pulmonary embolism or cardiac tamponade.
- Distributive Shock: Characterized by widespread vasodilation, leading to decreased blood pressure.
Shock Type Chart
- Hypovolemic Shock: Skin - ↓↓; Wedge Pressure (preload) - ↑; SVR (afterload) - ↓; Cardiac Output - ↓
- Cardiogenic Shock: Skin - Cold and clammy; Wedge Pressure (preload) - ↑; SVR (afterload) - ↑; Cardiac Output - ↓
- Obstructive Shock: Wedge Pressure (preload) - ↓ or ↑; SVR (afterload) - ↑; Cardiac Output - ↔ or ↓
- Distributive Shock: Skin - Warm and dry; Wedge Pressure (preload) - ↔ or ↓; SVR (afterload) - ↓↓; Cardiac Output - ↓ or ↑
Cellular Level Effects of Shock
- Cells shift to anaerobic metabolism, leading to inefficient ATP production and lactic acidosis.
- Prolonged shock causes cell membrane damage, loss of electrical gradient, and release of inflammatory mediators.
- Uncorrected, this process progresses to end-organ damage and multiple organ failure.
Stages of Shock
- Pre-shock (Compensated Shock): Body compensates for decreased perfusion with tachycardia, vasoconstriction, and maintained blood pressure.
- Shock (Decompensated Shock): Hypotension, tachycardia, tachypnea, altered mental status, cold/clammy skin, oliguria, and metabolic acidosis occur. Early organ dysfunction is present.
- End-Organ Dysfunction: Irreversible damage, multiorgan failure, and death occur.
Shock Treatment
- Airway Management: Ensure a patent airway (A)
- Breathing Support: Ensure adequate breathing (B)
- Circulation Restoration: Restore blood flow (C)
- Identify and Treat Cause: Address the underlying cause of shock.
Wedge Pressure
- Reflects left ventricular filling pressure and left atrial pressure.
- Measured via Swan-Ganz catheter.
Systemic Vascular Resistance (SVR)
- The amount of force blood encounters as it flows through the vasculature.
- Formula: MAP = CO x SVR
Cardiac Output (CO)
- The amount of blood pumped by the heart per minute.
- Formula: CO = SV x HR
Distributive Shock
- Caused by widespread peripheral vasodilation.
- Examples: Anaphylactic shock, neurogenic shock, septic shock.
- Leads to decreased SVR, initially with increased CO, but eventually decreases CO.
Septic Shock
- A subtype of distributive shock caused by infection.
- Characterized by systemic inflammatory response syndrome (SIRS).
Neurogenic Shock
- Caused by loss of sympathetic nervous system tone.
- Common with spinal cord injuries above T6.
- Leads to hypotension and bradycardia.
Anaphylactic Shock
- Severe allergic reaction mediated by IgE antibodies.
- Triggers release of histamine, heparin, and serotonin, leading to vasodilation.
- Common triggers: Foods, drugs, insect stings, pollen.
Adrenal Insufficiency
- Inability of the adrenal glands to produce adequate cortisol.
- Results in hypotension due to decreased SVR.
- Commonly seen in prolonged stress states, sepsis, and elderly patients.
Cardiogenic Shock
- Caused by heart failure, resulting in inadequate blood flow.
- Characterized by decreased CO and systemic hypoperfusion.
- Commonly caused by myocardial infarction, cardiomyopathy, arrhythmias, and mechanical heart problems.
Obstructive Shock
- Caused by obstruction of blood flow outside the heart.
- Examples: Cardiac tamponade, pulmonary embolism, tension pneumothorax.
Pulmonary Embolism
- A blood clot in the pulmonary arteries.
- Often migrates from deep vein thrombosis (DVT).
- Treatment: Hemodynamic stabilization, anticoagulation, thrombolytics in extreme cases.
Pericardial Tamponade
- Caused by fluid buildup in the pericardial sac, constricting the heart.
- Leads to Beck’s Triad: Hypotension, muffled heart sounds, and distended neck veins.
- Treatment: Pericardiocentesis or surgical decompression.
Tension Pneumothorax
- Air trapped in the pleural space, compressing the lung and heart.
- Causes: Trauma, infections, mechanical ventilation, iatrogenic procedures.
Hypovolemic Shock
- Caused by decreased intravascular volume, leading to decreased preload.
- Hemorrhagic type: Trauma, gastrointestinal bleeding, vascular rupture.
- Non-hemorrhagic type: Gastrointestinal losses, skin losses, third spacing, renal losses.
Blood Transfusion
- Used to increase oxygen carrying capacity and treat active bleeding.
- Goal Hgb: 7-10 g/dL for active bleeding, higher for certain conditions.
- Type and Screen (T&S) vs Type and Cross (T&C) for blood compatibility.
- Whole blood vs Blood components (FFP, platelets, cryoprecipitate).
Transfusion Reactions
- Febrile Reactions: Fever, chills, +/- antipyretics.
- Allergic Reactions: Urticaria, pruritis, +/- antihistamines. Severe cases: Bronchospasm, wheezing, anaphylaxis.
- Transfusion-associated Circulatory Overload (TACO): Respiratory distress, pulmonary edema, +/- diuretics.
- Transfusion-related Acute Lung Injury (TRALI): Acute hypoxemic respiratory distress, supportive care.
- Fatal Hemolysis: Fever, chills, back pain, flushing, dyspnea, tachycardia, and shock. Stop transfusion, IV fluids, cardiorespiratory support, hemolytic workup.
- Electrolyte Abnormalities: Hypocalcemia, Hyperkalemia, Hypokalemia.
- Infections: HIV, Hepatitis C, etc.
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Description
Explore the critical concept of shock in medical emergencies, focusing on its classifications and physiological impacts. This quiz covers hypovolemic, cardiogenic, obstructive, and distributive shock, highlighting their causes and symptoms. Test your knowledge on recognition and management of these life-threatening conditions.