Podcast
Questions and Answers
At what age is peak adult bone mass typically achieved?
At what age is peak adult bone mass typically achieved?
- Between 18 and 25 years (correct)
- Between 25 and 30 years
- Between 35 and 40 years
- Between 30 and 35 years
What factors can affect peak adult bone mass?
What factors can affect peak adult bone mass?
- Socioeconomic status, education level, and geographic location
- Dietary preferences, sleeping habits, and social interactions
- Genetic factors, nutrition, physical activity, medications, endocrine status, and general health (correct)
- Occupational status, marital status, and mental health
At what age do women typically experience primary osteoporosis?
At what age do women typically experience primary osteoporosis?
- By age 51 (correct)
- By age 30
- By age 40
- By age 60
What contributes to the development of osteopenia without associated bone loss?
What contributes to the development of osteopenia without associated bone loss?
What interventions can decrease the risk of fractures and associated disability later in life?
What interventions can decrease the risk of fractures and associated disability later in life?
What is secondary osteoporosis the result of?
What is secondary osteoporosis the result of?
Which gender typically develops larger, heavier bones?
Which gender typically develops larger, heavier bones?
What age range is associated with the manifestation of osteoporosis in men?
What age range is associated with the manifestation of osteoporosis in men?
What is the consequence of failure to develop optimal peak bone mass and low vitamin D levels?
What is the consequence of failure to develop optimal peak bone mass and low vitamin D levels?
What are some interventions that can decrease the risk of fractures and associated disability later in life?
What are some interventions that can decrease the risk of fractures and associated disability later in life?
Which group of women is at highest risk for osteoporosis?
Which group of women is at highest risk for osteoporosis?
What tool is used to estimate fracture risk and guide treatment decisions?
What tool is used to estimate fracture risk and guide treatment decisions?
What contributes to osteoporosis development?
What contributes to osteoporosis development?
What causes accelerated bone resorption in women?
What causes accelerated bone resorption in women?
What is used to diagnose osteoporosis?
What is used to diagnose osteoporosis?
Who has a greater peak bone mass and experiences osteoporosis later in life?
Who has a greater peak bone mass and experiences osteoporosis later in life?
What contributes to poor bone health?
What contributes to poor bone health?
At what age is baseline DEXA testing recommended for women?
At what age is baseline DEXA testing recommended for women?
What may be a cause of osteoporosis in men?
What may be a cause of osteoporosis in men?
When is osteoporosis undetectable on routine x-rays?
When is osteoporosis undetectable on routine x-rays?
What is the prevalence of osteoporosis in women older than 80 years?
What is the prevalence of osteoporosis in women older than 80 years?
What is a fragility fracture?
What is a fragility fracture?
Why are routine vertebral fracture screenings not recommended for older adults?
Why are routine vertebral fracture screenings not recommended for older adults?
What is the primary cause of net bone loss over time?
What is the primary cause of net bone loss over time?
What is the primary characteristic of osteoporosis?
What is the primary characteristic of osteoporosis?
What contributes to the greater prevalence of secondary causes of osteoporosis in men compared to women?
What contributes to the greater prevalence of secondary causes of osteoporosis in men compared to women?
Why are most residents of long-term care facilities at risk for bone fracture?
Why are most residents of long-term care facilities at risk for bone fracture?
What is the projected trend for the number of hip fractures and associated costs by 2040?
What is the projected trend for the number of hip fractures and associated costs by 2040?
What happens to the rate of bone resorption and bone formation in osteoporosis?
What happens to the rate of bone resorption and bone formation in osteoporosis?
What contributes to the altered absorption and excretion of dietary calcium in older adults?
What contributes to the altered absorption and excretion of dietary calcium in older adults?
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Study Notes
Osteoporosis and Fragility Fractures: Key Points
- Men are more likely than women to have secondary causes of osteoporosis, including the use of corticosteroids and excessive alcohol intake.
- The prevalence of osteoporosis in women older than 80 years is 50%.
- Most residents of long-term care facilities have a low bone mineral density (BMD) and are at risk for bone fracture.
- The number of hip fractures and associated costs are projected to double by 2040 due to the aging of the U.S. population.
- A fragility fracture is defined as one that occurs when a person falls from their natural height or with low velocity.
- Routine vertebral fracture screenings are not recommended for older adults, but 80% to 90% of these fractures can be seen incidentally on chest x-rays.
- Older adults absorb dietary calcium less efficiently and excrete it more readily through their kidneys.
- Osteoporosis is characterized by reduced bone mass, deterioration of bone matrix, and diminished bone architectural strength.
- Normal homeostatic bone turnover is altered in osteoporosis, with the rate of bone resorption maintained by osteoclasts being greater than the rate of bone formation maintained by osteoblasts.
- Compression fractures of the thoracic and lumbar spine, hip fractures, and Colles fractures of the wrist are common in osteoporosis.
- The gradual collapse of a vertebra may be asymptomatic, leading to kyphosis, loss of height, and postural changes.
- Age-related loss of bone mass begins soon after peak bone mass is achieved, with decreased calcitonin and estrogen, and increased parathyroid hormone contributing to net bone loss over time.
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