Osteoporosis Overview and Fracture Risks
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Questions and Answers

What is a major consequence of osteoporosis?

  • Enhanced bone remodeling
  • Increased bone mineral density
  • Low-impact fragility fractures (correct)
  • Increased skeletal mass
  • Which of the following is a common fracture associated with aging and osteoporosis?

  • Clavicle fracture
  • Fracture of the distal radius (correct)
  • Proximal femur fracture
  • Fracture of the tibia
  • Which group is most likely to experience osteoporotic fractures?

  • Men under 50 years old
  • Postmenopausal women over 50 years old (correct)
  • Children with low BMI
  • Athletes engaged in weight training
  • What is the primary mechanism by which bisphosphonates function in the treatment of osteoporosis?

    <p>Inhibiting osteoclastic bone resorption</p> Signup and view all the answers

    What is the recommended threshold for a T score to diagnose osteoporosis?

    <p>-2.5</p> Signup and view all the answers

    Which of the following drugs is administered annually for osteoporosis treatment?

    <p>Zolendronate</p> Signup and view all the answers

    Which lifestyle factor is a risk for developing osteoporosis?

    <p>Low body weight</p> Signup and view all the answers

    For patients with low to moderate fracture risk, what is the recommended action after 3-5 years of bisphosphonate therapy?

    <p>A bisphosphonate holiday of up to 5 years</p> Signup and view all the answers

    At what age does the risk of hip fracture double every five years?

    <p>70 years</p> Signup and view all the answers

    What is the primary indication for denosumab in osteoporosis treatment?

    <p>Monoclonal antibody to RANKL</p> Signup and view all the answers

    Which of the following drugs is known to be a potential cause of secondary osteoporosis?

    <p>Glucocorticoids</p> Signup and view all the answers

    What is the FRAX tool used for in osteoporosis management?

    <p>Predicting 10-year fracture risk</p> Signup and view all the answers

    What T score indicates osteoporosis?

    <p>T score less than -2.5</p> Signup and view all the answers

    What is the suggested daily supplementation of calcium for osteoporosis management?

    <p>1200mg</p> Signup and view all the answers

    In women under 60 years of age, which of the following conditions can warrant hormone replacement therapy for osteoporosis?

    <p>Less than 10 years post-menopause with vasomotor symptoms</p> Signup and view all the answers

    What is a significant risk factor for secondary osteoporosis outlined by the ABCDE mnemonic?

    <p>Addictions</p> Signup and view all the answers

    Study Notes

    Osteoporosis Consequences

    • Osteoporosis can lead to fractures, especially in the hip, spine, and wrist.
    • Fractures can lead to pain, disability, and loss of independence.

    Osteoporosis Fractures

    • Hip fractures are a common fracture associated with aging and osteoporosis.
    • Women are more likely than men to experience osteoporotic fractures.

    Bisphosphonates Mechanism

    • Bisphosphonates work by inhibiting the activity of osteoclasts, cells responsible for bone resorption.

    Osteoporosis Diagnosis

    • A T score of -2.5 or lower is the standard for diagnosing osteoporosis.

    Osteoporosis Treatment

    • Denosumab is administered annually for osteoporosis treatment.

    Osteoporosis Risk Factors

    • Low calcium intake is a risk for developing osteoporosis.

    Bisphosphonate Therapy

    • For patients with low to moderate fracture risk, a "drug holiday" is recommended after 3-5 years of bisphosphonate therapy.

    Osteoporosis Age Risk

    • The risk of hip fracture doubles every five years after the age of 50.

    Denosumab Indication

    • Denosumab is used to treat osteoporosis in patients at high risk for fractures.

    Secondary Osteoporosis

    • Corticosteroids can cause secondary osteoporosis.

    FRAX Tool

    • The FRAX tool estimates the 10-year fracture risk for individuals.

    T Score Interpretation

    • A T score of -2.5 or lower indicates osteoporosis.

    Calcium Supplementation

    • 1200 mg daily calcium supplementation is suggested for osteoporosis management.

    Hormone Replacement Therapy

    • In women under 60 years of age, early menopause can warrant hormone replacement therapy for osteoporosis.

    Secondary Osteoporosis Risk Factors

    • Endocrine disorders are a significant risk factor for secondary osteoporosis outlined by the ABCDE mnemonic.

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    Description

    This quiz covers the characteristics of osteoporosis, including its causes, clinical profile, and common fractures associated with the condition. Learn about the impact of gender and age on osteoporosis prevalence and the importance of bone density in overall health.

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