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Organ Donation and Screening

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Questions and Answers

What type of reaction does the TST elicit?

Immune response

Allergic reaction

Hypersensitivity reaction (correct)

Inflammatory reaction

Which infection is a transplant recipient at risk for, and involves detection of specific IgG antibodies?

Mycobacterium tuberculosis infection

Toxoplasmosis (correct)

Histoplasmosis

Strongyloidiasis

What measure do GRAs evaluate in relation to M.tuberculosis infection?

T cell release of interferon gamma (IFN-γ) (correct)

B cell production of antibodies

Cytokine secretion

Macrophage activation

How is Strongyloidiasis diagnosed in transplant recipients?

Serial stool ova and parasite examinations Signup and view all the answers

What is the test with high sensitivity and specificity for diagnosing strongyloidiasis?

Strongyloides IgG measured by ELISA Signup and view all the answers

What is the estimated incidence of post-transplant histoplasmosis?

Rare Signup and view all the answers

What is the primary goal of pretransplant screening?

To assess the risks for common posttransplant infections Signup and view all the answers

Which test is recommended by the CDC for syphilis screening in transplant candidates?

TP-PA assay Signup and view all the answers

What is the purpose of evaluating all transplant candidates for latent TB infection?

To assess the risk of latent TB infection Signup and view all the answers

Which test assesses cellular immune response to detect latent TB infection?

Interferon gamma release assays (IGRA) Signup and view all the answers

Why is a detailed social history considered important in the evaluation of syphilis in SOT candidates?

To identify potential exposure risks Signup and view all the answers

In syphilis screening, what do non-treponemal tests detect?

Antibodies against cardiolipin Signup and view all the answers