Opioids Agonists and Antagonists in Medicine
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Questions and Answers

Which alkaloid is the chief component of crude opium?

  • Thebaine
  • Codeine
  • Papaverine
  • Morphine (correct)
  • What is the generic term for all substances (exogenous or endogenous) with morphine-like properties?

  • Opioid (correct)
  • Alkaloid
  • Opiate
  • Endorphin
  • Which opioid is classified as a strong agonist?

  • Oxycodone
  • Buprenorphine
  • Methadone (correct)
  • Codeine
  • Which receptor sub-types do opioids function with differing potencies?

    <p>Mu, Kappa, and Delta</p> Signup and view all the answers

    What are drugs called that produce a less than maximal response and have low intrinsic activity?

    <p>Partial Agonists</p> Signup and view all the answers

    Which opioid class generally exerts influence through regulation of the hypothalamus?

    <p>Neuroendocrine</p> Signup and view all the answers

    What is a predictor of opioid-related adverse events according to the text?

    <p>High doses of opioids</p> Signup and view all the answers

    Which opioid is associated with decreased RBF and enhanced renal tubular Na+ absorption?

    <p>Morphine</p> Signup and view all the answers

    Which opioid class generally causes urinary retention and caution for renal calculi colic?

    <p>Strong agonists</p> Signup and view all the answers

    Which opioid-related factor is related to chronic obstructive pulmonary disease?

    <p>Sleep apnea</p> Signup and view all the answers

    Which opioid has a reversal effect for 48 hours in heroin addiction?

    <p>Naltrexone</p> Signup and view all the answers

    Which opioid metabolism pathway leads to potent metabolites for certain drugs?

    <p>P450 system pathway</p> Signup and view all the answers

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