Opioids Agonists and Antagonists in Medicine

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Which alkaloid is the chief component of crude opium?

Morphine

What is the generic term for all substances (exogenous or endogenous) with morphine-like properties?

Opioid

Which opioid is classified as a strong agonist?

Methadone

Which receptor sub-types do opioids function with differing potencies?

<p>Mu, Kappa, and Delta</p> Signup and view all the answers

What are drugs called that produce a less than maximal response and have low intrinsic activity?

<p>Partial Agonists</p> Signup and view all the answers

Which opioid class generally exerts influence through regulation of the hypothalamus?

<p>Neuroendocrine</p> Signup and view all the answers

What is a predictor of opioid-related adverse events according to the text?

<p>High doses of opioids</p> Signup and view all the answers

Which opioid is associated with decreased RBF and enhanced renal tubular Na+ absorption?

<p>Morphine</p> Signup and view all the answers

Which opioid class generally causes urinary retention and caution for renal calculi colic?

<p>Strong agonists</p> Signup and view all the answers

Which opioid-related factor is related to chronic obstructive pulmonary disease?

<p>Sleep apnea</p> Signup and view all the answers

Which opioid has a reversal effect for 48 hours in heroin addiction?

<p>Naltrexone</p> Signup and view all the answers

Which opioid metabolism pathway leads to potent metabolites for certain drugs?

<p>P450 system pathway</p> Signup and view all the answers

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