Opioids Agonists and Antagonists in Medicine
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Questions and Answers

Which alkaloid is the chief component of crude opium?

  • Thebaine
  • Codeine
  • Papaverine
  • Morphine (correct)

What is the generic term for all substances (exogenous or endogenous) with morphine-like properties?

  • Opioid (correct)
  • Alkaloid
  • Opiate
  • Endorphin

Which opioid is classified as a strong agonist?

  • Oxycodone
  • Buprenorphine
  • Methadone (correct)
  • Codeine

Which receptor sub-types do opioids function with differing potencies?

<p>Mu, Kappa, and Delta (B)</p> Signup and view all the answers

What are drugs called that produce a less than maximal response and have low intrinsic activity?

<p>Partial Agonists (A)</p> Signup and view all the answers

Which opioid class generally exerts influence through regulation of the hypothalamus?

<p>Neuroendocrine (D)</p> Signup and view all the answers

What is a predictor of opioid-related adverse events according to the text?

<p>High doses of opioids (D)</p> Signup and view all the answers

Which opioid is associated with decreased RBF and enhanced renal tubular Na+ absorption?

<p>Morphine (D)</p> Signup and view all the answers

Which opioid class generally causes urinary retention and caution for renal calculi colic?

<p>Strong agonists (D)</p> Signup and view all the answers

Which opioid-related factor is related to chronic obstructive pulmonary disease?

<p>Sleep apnea (B)</p> Signup and view all the answers

Which opioid has a reversal effect for 48 hours in heroin addiction?

<p>Naltrexone (D)</p> Signup and view all the answers

Which opioid metabolism pathway leads to potent metabolites for certain drugs?

<p>P450 system pathway (D)</p> Signup and view all the answers

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