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Opioid Analgesic Drugs Overview
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Opioid Analgesic Drugs Overview

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Questions and Answers

Which type of opioid drug is known for its spasmolytic effect on smooth muscles?

  • Meperidine
  • Morphine
  • Papaverine (correct)
  • Codeine
  • What is the main constituent of natural opium alkaloids?

  • Codeine
  • Morphine (correct)
  • Diacetyl Morphine
  • Papaverine
  • Which opioid drug is used parenterally due to its low oral bioavailability of 25%?

  • Meperidine
  • Diacetyl Morphine
  • Fentanyl
  • Morphine (correct)
  • What liver process conjugates morphine with glucuronic acid to form the active morphine-6-conjugate?

    <p>Glucuronidation</p> Signup and view all the answers

    Which opioid receptor site is stimulated by morphine and related compounds in the CNS and peripheral tissues?

    <p>Opioid receptors</p> Signup and view all the answers

    Which opioid drug is classified as a synthetic opioid agonist?

    <p>Methadone</p> Signup and view all the answers

    Among the natural alkaloids, which one has a spasmogenic effect on smooth muscles?

    <p>Morphine</p> Signup and view all the answers

    What is the main difference between natural opium alkaloid morphine and papaverine?

    <p>Spasmolytic effect</p> Signup and view all the answers

    Which endogenous natural opioid peptides bind to opioid receptors in the body?

    <p>Enkephalins and Endorphins</p> Signup and view all the answers

    What is the main reason for using morphine parenterally instead of orally?

    <p>Low oral bioavailability</p> Signup and view all the answers

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