Nutrition Research Methods: Specific Nutritional Biomarkers
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Questions and Answers

What is the main limitation of using urinary vitamin C concentration as a biomarker of overall vitamin C intake?

  • It is not affected by endogenous sources of vitamin C
  • It is influenced by dietary sources of vitamin C
  • It is mainly assessed in plasma
  • It cannot accurately reflect long-term vitamin C intake (correct)
  • Why does blood calcium have limited value as a marker of calcium status?

  • It fluctuates widely based on short-term intake
  • It is tightly controlled by the liver
  • It is influenced by endogenous and exogenous sources of calcium (correct)
  • It is not correlated with dietary calcium intake
  • Which form of vitamin E shows a higher correlation with intake in adipose tissue?

  • β-tocopherol
  • δ-tocopherol
  • α-tocopherol
  • γ-tocopherol (correct)
  • What is the main source of dietary vitamin D?

    <p>Fortified foods</p> Signup and view all the answers

    Which micronutrient can be measured in erythrocytes and is highly correlated with plasma levels?

    <p>Vitamin E</p> Signup and view all the answers

    Which biomarker can be used as a marker for fat intake?

    <p>Individual fatty acids</p> Signup and view all the answers

    What is the key limitation of using 24-hour urinary nitrogen as a biomarker for protein intake?

    <p>It is not feasible to collect 24-hour urine samples</p> Signup and view all the answers

    Why is there currently no biomarker for total carbohydrate intake?

    <p>Carbohydrates undergo extensive metabolism</p> Signup and view all the answers

    Which nutrient's bioactive form can be measured in serum and plasma?

    <p>Vitamin A</p> Signup and view all the answers

    What cannot be synthesised de novo by humans and can be used as a marker of intake for fat?

    <p>$\omega − 3$ (α-linoleic acid)</p> Signup and view all the answers

    What can be used as a biomarker of overall vitamin C intake?

    <p>Plasma concentration of vitamin C</p> Signup and view all the answers

    Which form of vitamin E is highly correlated with plasma vitamin E and can be measured in erythrocytes?

    <p>α-tocopherol</p> Signup and view all the answers

    Which mineral status assessment shows significant but variable correlations between intake from dietary sources and plasma concentration?

    <p>Vitamin K status</p> Signup and view all the answers

    What is commonly used as a measure of vitamin D status?

    <p>Plasma 25(OH)D level</p> Signup and view all the answers

    What is the standard method for measuring urinary nitrogen?

    <p>Kjeldahl method</p> Signup and view all the answers

    Which nutrient's intake shows a strong correlation with folic acid and folate in red blood cells, serum, and plasma?

    <p>Vitamin C</p> Signup and view all the answers

    Which biomarker can be used as a predictor of total sugar intake?

    <p>Sum of urinary sucrose and fructose</p> Signup and view all the answers

    Why is there currently no biomarker for total carbohydrate intake?

    <p>The complex nature of carbohydrates and their extensive metabolism make it challenging to identify a specific biomarker.</p> Signup and view all the answers

    What is the bioactive form of vitamin A that can be measured in serum and plasma?

    <p>Retinol</p> Signup and view all the answers

    Which specimen can be used to measure individual fatty acids as a biomarker of fat intake?

    <p>Blood</p> Signup and view all the answers

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