Nutrition and Trace Elements Quiz
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Questions and Answers

What is the primary function of iron in the human body?

  • Enhances insulin action
  • Delivers oxygen to cells (correct)
  • Helps with lipid metabolism
  • Strengthens tooth enamel
  • Which group is most at risk for zinc deficiency?

  • Vegetarians (correct)
  • Infants and preschool children
  • Elderly individuals
  • Athletes
  • What symptom may indicate selenium deficiency?

  • Enlarged thyroid
  • Poor growth
  • Muscle pain and weakness (correct)
  • Decreased immune function
  • What is the upper limit (UL) for copper intake in adults?

    <p>10 mg/day</p> Signup and view all the answers

    Which trace element is specifically involved in thyroid hormone synthesis?

    <p>Iodine</p> Signup and view all the answers

    Which of the following foods contains high levels of fluorine?

    <p>Fluoridated water</p> Signup and view all the answers

    What is a possible side effect of manganese toxicity?

    <p>Nerve damage</p> Signup and view all the answers

    What condition may arise from chromium deficiency?

    <p>High blood glucose</p> Signup and view all the answers

    What is the recommended intake of manganese for adults?

    <p>1.8-2.3 mg/day</p> Signup and view all the answers

    Which trace element's toxicity can lead to decreased copper absorption?

    <p>Zinc</p> Signup and view all the answers

    What is the risk associated with Vitamin B12 deficiency?

    <p>Pernicious anemia</p> Signup and view all the answers

    Which group is at the highest risk of Vitamin C deficiency?

    <p>Alcoholics</p> Signup and view all the answers

    What major function does Vitamin D serve in the body?

    <p>Bone maintenance</p> Signup and view all the answers

    Which is a symptom of Choline toxicity?

    <p>Liver damage</p> Signup and view all the answers

    What is the upper limit of intake for Vitamin A in micrograms?

    <p>3000 µg/day</p> Signup and view all the answers

    Which food source is high in Vitamin E?

    <p>Leafy greens</p> Signup and view all the answers

    Which symptom is associated with a deficiency of Calcium?

    <p>Osteoporosis</p> Signup and view all the answers

    Which vitamin can mask a deficiency in B12 if consumed in excess?

    <p>Folate</p> Signup and view all the answers

    What is the recommended intake of Vitamin K for adults?

    <p>90-120 µg/day</p> Signup and view all the answers

    What mineral is necessary for nerve transmission?

    <p>Calcium</p> Signup and view all the answers

    Which of the following is NOT a source of Vitamin D?

    <p>Citrus fruits</p> Signup and view all the answers

    What upper limit is set for Vitamin E intake from supplements?

    <p>1000 mg/day</p> Signup and view all the answers

    Which group is primarily at risk for Vitamin D deficiency?

    <p>Elderly with dark skin</p> Signup and view all the answers

    Which phytochemical is known to provide antioxidant protection and may decrease the risk of muscular degeneration?

    <p>Carotenoids</p> Signup and view all the answers

    Which food source is rich in phytosterols, which have been shown to decrease cholesterol absorption?

    <p>Nuts</p> Signup and view all the answers

    What is the primary biological activity of sulforaphane found in cruciferous vegetables?

    <p>Detoxifies carcinogens</p> Signup and view all the answers

    Which vitamin deficiency is characterized by dermatitis, nausea, and hallucinations?

    <p>Biotin</p> Signup and view all the answers

    Which class of phytochemicals is known to mimic estrogen and may reduce the risk of osteoporosis?

    <p>Phytoestrogens</p> Signup and view all the answers

    Which nutrient serves as a coenzyme in the synthesis and breakdown of lipids?

    <p>Pantothenic acid</p> Signup and view all the answers

    Which of the following is a food source high in flavonols that can help block carcinogens?

    <p>Onions</p> Signup and view all the answers

    What is a notable characteristic of niacin deficiency?

    <p>Pellagra</p> Signup and view all the answers

    Which phytochemical, found in turmeric, acts as an antioxidant and reduces carcinogen formation?

    <p>Curcumin</p> Signup and view all the answers

    What effect do polyphenols like flavanoids have on blood vessels?

    <p>Strengthen capillary blood vessels</p> Signup and view all the answers

    Which nutrient is synthesized by bacteria in the gut and plays a role in amino acid metabolism?

    <p>Biotin</p> Signup and view all the answers

    Saponins are known to do which of the following?

    <p>Reduce cancer risk</p> Signup and view all the answers

    What are the primary functions of vitamin B6?

    <p>Coenzyme in protein metabolism and neurotransmitter synthesis</p> Signup and view all the answers

    Which phytochemical is primarily found in hot peppers and modulates blood clotting?

    <p>Capsaicin</p> Signup and view all the answers

    Study Notes

    Phytochemicals in foods:

    • Carotenoids: (alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein, zeaxanthin, lycopene)

      • Food sources:

        • Apricots, carrots, cantaloupe, tomatoes, peppers, sweet potatoes, squash, broccoli, spinach, leafy greens
      • Biological activities and possible effects:

        • Some are converted to vitamin A, provide antioxidant protection, some decrease the risk of muscular degeneration
    • polyphenols: flavonols (quercetin, kaempferol, myricetin), flavones (apigenin), flavanols (catechins), anthocyanidins (cyanidin, delphinidin):

      • Food sources:

        • Berries, citrus fruit, onions, purple grapes, green tea, red wine, chocolate
      • Biological activities and possible effects:

        • Make capillary blood vessels stronger, block carcinogens, slow the growth of cancer cells
    • Phytoestrogens including lignins, isoflavones such as genistein, biochanin A, daidzein:

      • Food sources:

        • Tofu, soy milk, soy beans, flax seed, rye bread
      • Biological activities and possible effects:

        • Mimic effect of estrogen, induce cancer cell death, slow the growth of cancer cells, reduce blood cholesterol, may reduce risk of osteoporosis 
    • Phytosterols: beta-sitosterol, stigmasterol, campesterol

      • Food sources:

        • Nuts, seeds, legumes
      • Biological activities and possible effects:

        • Decrease cholesterol absorption, reduce the risk of colon cancer by slowing growth of colon cells 
    • Capsaicin

      • Food sources:

        • Hot peppers
      • Biological activities and possible effects:

        • Modulates blood clotting 
    • Glucosinolates, isothiocyanates, indoles:

      • Food sources:

        • Broccoli, brussels sprouts, cabbage
      • Biological activities and possible effects:

        • Increase the activity of enzymes that deactivate carcinogens, alter estrogen metabolism, affect the regulation of gene expression 
    • Sulfides and allium compounds:

      • Food sources:

        • Onions, garlic, leeks, chives 
      • Biological activities and possible effects:

        • Deactivate carcinogens, kill bacteria, protect against heart disease
    • Inositol

      • Food sources:

        • Sesame seeds and soy beans
      • Biological activities and possible effects:

        • Protects against free radicals, protects against cancer
    • Saponins

      • Food sources:

        • Beans and herbs 
      • Biological activities and possible effects:

        • Decrease cholesterol absorption, decrease cancer risk, antioxidant 
    • Ellagic acid

      • Food sources:

        • Nuts, grapes, strawberries 
      • Biological activities and possible effects:

        • Anticancer properties, prevents formation of carcinogens in the stomach
    • Tannins, catechins

      • Food sources:

        • Tea, red wine
      • Biological activities and possible effects:

        • Antioxidants, cancer protection
    • Curcumin

      • Food sources:

        • Turmeric, mustard 
      • Biological activities and possible effects:

        • Reduces carcinogen formation, antioxidant, anti-inflammatory 
    • Sulforaphane

      • Food sources:

        • Broccoli, cruciferous vegetables
      • Biological activities and possible effects:

        • Detoxifies carcinogens, protect animals from breast cancer
    • Limonene

      • Food sources:

        • Citrus fruit peels
      • Biological activities and possible effects:

        • Inhibits cancer cell growth 

    Water soluble vitamins and choline:

    • Thiamin (B1): 

      • Sources:

        • Pork, whole and enriched grains, seeds, nuts, legumes
    • Recommended intake for adults:

      • 1.1-1.2mg/day
    • Major functions:

      • Coenzyme in acetyl-CoA formation and citric acid cycle, acetylcholine synthesis, nerve function
    • Deficiency diseases and symptoms:

      • Berberi: weakness, apathy, irritability, nerve tingling, poor coordination, paralysis, heart changes such as rapid heart beat, enlargement of the heart, congestive heart failure 
    • Groups at risk:

      • Alcoholics, those living in poverty
    • No reported toxicity 

    • Riboflavin (B2):

      • Sources: 

        • dairy products, whole and enriched grains, leafy green vegetables, meats
      • Intake for adults: 

        • 1.1-1.3 mg/day
      • Major functions:

        • Coenzyme in citric acid cycle, lipid metabolism, and electron transport chain
      • Deficiency diseases and symptoms:

        • Ariboflavinosis: inflammation of mouth and tongue, cracks at corner of the mouth 
      • No groups at risk

      • No reported toxicity 

    • Niacin (vitamin B3): 

      • Sources: 

        • Beef, chicken, fish, peanuts, legumes, whole and enriched grains, can be made from tryptophan
      • Recommended intake for adults:

        • 14-16 mg NE/day
      • Major functions:

        • Coenzyme in glycolysis, citric acid cycle, electron transport chain, and lipid synthesis and breakdown
      • Deficiency diseases and symptoms:

        • Pellagra: diarrhea, dermatitis on areas exposed to the sun, dementia 
      • Groups at risk:

        • Those consuming a limited diet based on corn, alcoholics
      • Toxicity:

        • Flushing, nausea, rash, tingling extremities 
      • UL: 35 mg/day from fortified foods and supplements 

    • Biotin:

    • Sources:

      • Liver, egg yolks, synthesized bacteria in the gut
    •  Recommended intake for adults:

      • 30 µg/day
    • Major functions:

      • Coenzyme in glucose and fatty acid synthesis and amino acid metabolism
    • Deficiency diseases and symptoms:

      • Dermatitis, nausea, depression, hallucinations 
    • Groups at risk of deficiency:

      • Those consuming large amounts of egg whites, alcoholics 
    • No reported toxicity 

    • Pantothenic acid (calcium pantothenate):

      • Sources: 

        • Meat, legumes, whole grains, widespread in foods 
      • Recommended intake for adults:

        • 5 mg/day
      • Major functions:

        • Coenzyme in citric acid cycle and lipid synthesis and breakdown 
      • Deficiency diseases and symptoms:

        • Fatigue, rash
      • Groups at risk of deficiency:

        • Alcoholics
      • No reported toxicity 

    • Vitamin B6 (pyridoxine, pyridoxal phosphate, pyridoxamine):

      • Sources:

        • Meat, fish, poultry, liver, legumes, whole grains, nuts, seeds
      • Recommended intake for adults:

        • 1.4-1.7 mg/day
      • Major functions:

        • Coenzyme in protein and amino acid metabolism, neurotransmitter and hemoglobin synthesis 
      • Deficiency diseases and symptoms:

        • Headache, convulsions, other neurological symptoms, decreased immune function, poor growth, anemia 
      • Groups at risk of deficiency:

        • Alcoholics
      • Toxicity: 

        • numbness, nerve damage
      • UL: 100 mg/day

    • Folate (folic acid, folacin, pteroylglutamic acid):

      • Sources:

        • Leafy green vegetables, legumes, nuts, seeds, enriched grains, oranges, liver 
      • Recommended intake for adults:

        • 400 µg DFE/day
      • Major functions:

        • Coenzyme in DNA synthesis and amino acid metabolism
      • Deficiency diseases and symptoms:

        • Macrocytic anemia, inflammation of tongue, diarrhea, poor growth, neural tube defects
      • Groups at risk of deficiency:

        • Pregnant women, premature infants, alcoholics 
      • Toxicity:

        • Masks B12 deficiency 
      • UL: 1000 µg/day from fortified foods and supplements 

    • Vitamin B13 (cobalamin, cyanocobalamin): 

      • Sources:

        • Animal products
      • Recommended intake for adults:

        • 2.4 µg/day
      • Major functions:

        • Coenzyme in folate and fatty acid metabolism; nerve function
      • Deficiency diseases and symptoms:

        • Pernicious anemia, macrocytic anemia, nerve damage
      • Groups at risk of deficiency:

        • Vegans, elderly, those with stomach or intestinal disease
      • No reported toxicity 

    • Vitamin C (ascorbic acid, ascorbate):

      • Sources: 

        • Citrus fruits, broccoli, strawberries, greens, peppers, potatoes 
      • Recommended intake for adults:

        • 75-90 mg/day
      • Major functions:

        • Coenzyme in collagen synthesis, hormone and neurotransmitter synthesis, antioxidant 
      • Deficiency diseases and symptoms:

        • Scurvy: poor wound healing, bleeding gums, loose teeth, bone fragility, joint pain, pinpoint hemorrhages 
      • Groups at risk of deficiency:

        • Alcoholics, elderly 
      • Toxicity:

        • GI distress, diarrhea 
      • UL: 2000 mg/day

    • Choline:

      • Sources:

        • Egg yolks, organ meats, leafy greens, nuts, body synthesis
      • Recommended intake for adults:

        • 425-550 mg/day 
      • Major functions:

        • Synthesis of cell membranes and neurotransmitters
      • Deficiency diseases and symptoms:

        • Liver dysfunction 
      • Toxicity:

        • Sweating, low blood pressure, liver damage
      • UL: 3500 mg/day

    A summary of the fat soluble vitamins:

    • Vitamin A (retinol, retinal, retinoic acid, vitamin A acetate, retinyl palmitate, beta-carotene, etc.)

      • Sources: 

        • retinol: liver, fish, fortified milk and margarine, butter, eggs

        • Carotenoids: carrots, leafy greens, sweet potatoes, broccoli, apricots, cantaloupe

      • Recommended intake for adults:

        • Women: 700 µg/day

        • Men: 900 µg/day

      • Major functions:

        • Vision, health of cornea and other epithelial tissue, cell differentiation, reproduction, immune function
      • Deficiency diseases and symptoms:

        • Night blindness, xerophthalmia, poor growth, dry skin, impaired immunity 
      • Groups at risk of deficiency:

        • Those with a limited diet (children and pregnant women), those consuming low fat or low protein diets 
      • Toxicity:

        • Headache, vomiting, hair loss, liver damage, skin changes, bone and muscle pain, fractures, birth defects
      • UL: 3,000 µg/day 

    • Vitamin D (calciferol, cholecalciferol, ergocalciferol, dihydroxy vitamin D):

      • Sources:

        • Egg yolk, liver, fish oils, tuna, salmon, fortified milk, synthesis from sunlight
      • Recommended intake for adults:

        • 15-20 µg/day
      • Major functions:

        • Absorption of calcium and phosphorus, maintenance of bone 
      • Deficiency diseases and symptoms:

        • Rickets in children: abnormal growth, misshapen bones, bowed legs, soft bones

        • Osteomalacia in adults: weak bones and bone and muscle pain 

      • Groups at risk of deficiency:

        • Some breastfed infants, children and elderly, especially those with dark skin and little sun exposure, people with kidney disease 
      • Toxicity:

        • Calcium deposits in soft tissues, growth retardation, kidney damage
      • UL: 100 µg/day

    • Vitamin E (tocopherol, alpha-tocopherol):

      • Sources:

        • Vegetable oils, leafy greens, seeds, nuts, peanuts
      • Recommended intake for adults:

        • 15 mg/day
      • Major functions:

        • Antioxidant, protects cell membranes 
      • Deficiency diseases and symptoms:

        • Broken red blood cells, nerve damage 
      • Groups at risk of deficiency:

        • Those with poor fat absorption, premature infants
      • Toxicity:

        • Inhibition of vitamin K activity 
      • UL: 1000 mg/day 

    • Vitamin K (phylloquinones, menaquinone):

      • Sources:

        • Vegetable oils, leafy greens, synthesis by intestinal bacteria
      • Recommended intake for adults:

        • 90-120 µg/day
      • Major functions:

        • Coenzyme for synthesis of blood clotting proteins and proteins in bone
      • Deficiency diseases and symptoms:

        • Hemorrhage 
      • Groups at risk of deficiency:

        • Newborns (especially premature), people on long term antibiotics
      • Toxicity:

        • Anemia and brain damage in infants 
      • UL: Not determined 

    Summary of calcium, phosphorus, magnesium, and sulfur

    • Calcium:

      • Sources: 

        • milk and alternatives, fish consumed with bones, leafy green vegetables, fortified foods
      • Recommended intake for adults:

        • 1000-1200 mg/day
      • Major functions:

        • Bone and tooth structure, nerve transmission, muscle contraction, blood clotting, blood pressure regulation, hormone secretion
      • Deficiency disease and symptoms:

        • Increased risk of osteoporosis 
      • Groups at risk of deficiency:

        • Post menopausal women, elderly, those who consume vegan diet, lactose intolerance, kidney disease 
      • Toxicity:

        • Elevated blood calcium, calcification of the kidney, kidney stones, reduced absorption of other mineral 
      • UL: 2500 mg/day

      • UL: 70+ 2000 mg/day

    • Phosphorus:

      • Sources:

        • Meat, milk products, cereals, baked goods
      • Recommended intake for adults:

        • 700 mg/day
      • Major functions:

        • Structure of bones and teeth, membranes, ATP, DNA, acid base balance
      • Deficiency diseases and symptoms:

        • Bone loss, weakness, lack of appetite
      • Groups at risk of deficiency:

        • Premature infants, alcoholics, elderly
      • Toxicity:

        • Calcium resorption of bone 
      • UL: 4000 mg/day

    • Magnesium:

      • Sources:

        • Greens, whole grains, nuts, seeds
      • Recommended intake for adults:

        • 310-420 mg/day
      • Major functions:

        • Bone structure, ATP stabilization, enzyme activity, nerve and muscle function
      • Deficiency diseases and symptoms:

        • Nausea, vomiting, weakness, muscle pain, irregular heart beat 
      • Groups at risk of deficiency:

        • Alcoholics, those with kidney and gastrointestinal disease
    •  Toxicity:

      • Nausea, vomiting, diarrhea, low blood pressure
    • UL: 350 mg/day non food sources

    • Sulfur:

    • Sources:

      • High protein foods, preservatives 
    • Recommended intake for adults:

      • Not specified 
    • Major functions:

      • Part of amino acids, vitamins, acid base balance
    • Deficiency diseases and symptoms:

      • None when protein needs are met 
    • Groups at risk of deficiency:

      • None
    • Toxicity:

      • None
    • No UL

    A summary of trace elements:

    • Iron:

      • Sources:

        • Red meats, leafy greens, dried fruit, whole and enriched grains
      • Recommended intake for adults:

        • 8-18 mg/day
      • Major functions:

        • Part of hemoglobin, which delivers oxygen to cells; myoglobin which holds oxygen in muscle; and electron carriers in the electron transport chain; needed for immune function 
      • Deficiency diseases and symptoms:

        • Iron deficiency anemia: fatigue, weakness, small pale red blood cells, low hemoglobin
      • Groups at risk of deficiency:

        • Infants and preschool children, adolescents, women of child bearing age, pregnant women, athletes 
      • Toxicity:

        • Gastrointestinal upset, liver damage
      • UL: 45 mg/day

    • Zinc:

      • Sources:

        • Meat, seafood, whole grains, eggs
      • Recommended intake for adults:

        • 8-11 mg/day
      • Major functions:

        • Regulates protein synthesis; functions in growth, development, wound healing, immunity, antioxidant protection 
      • Deficiency disease and symptoms:

        • Poor growth and development, skin rashes, decreased immune function
      • Groups at risk of deficiency:

        • Vegetarians, low income children, elderly 
      • Toxicity:

        • Decreased copper absorption, depressed immune function
      • UL: 40 mg/day

    • Copper:

      • Sources:

        • Organ meats, nuts, seeds, whole grains, seafood, cocoa 
      • Recommended intake for adults:

        • 900 µg/day
      • Major functions:

        • A part of proteins needed for iron absorption, lipid metabolism, collagen synthesis, nerve and immune function, antioxidant protection 
      • Deficiency diseases and symptoms:

        • Anemia, poor growth, bone abnormalities 
      • Groups at risk of deficiency:

        • Those who over supplement zinc
      • Toxicity:

        • Vomiting 
      • UL: 10 mg/day

    • Manganese:

      • Sources: 

        • Nuts, legumes, whole grains, tea
      • Recommended intake for adults:

        • 1.8-2.3 mg/day
      • Major functions:

        • Functions in carbohydrate and lipid metabolism and antioxidant protection 
      • Deficiency diseases and symptoms:

        • Growth retardation
      • Toxicity:

        • Nerve damage
      • UL: 11 mg/day

    • Selenium:

      • Sources:

        • Organ meats, seafood, eggs, whole grains
      • Recommended intake for adults: 

        • 55 µg/day
      • Major functions:

        • Antioxidant protection as part of glutathione peroxidase, synthesis of thyroid hormones, spares vitamin E
      • Deficiency diseases and symptoms:

        • Muscle pain, weakness, keshan disease 
      • Groups at risk of deficiency:

        • Populations in areas with low selenium soil
      • Toxicity:

        • Nausea, diarrhea, vomiting, fatigue, hair changes 
      • UL: 400 µg/day

    • Iodine:

      • Sources:

        • Iodized salt, salt water fish, seafood, dairy
      • Recommended intake for adults:

        • 150 µg/day
      • Major functions:

        • Needed for synthesis of thyroid hormones
      • Deficiency diseases and symptoms:

        • Goiter, cretinism, intellectual development disorder, growth and developmental abnormalities
      • Groups at risk of deficiency:

        • Populations in areas with low-iodine soil and where iodized salt is not used 
      • Toxicity:

        • Enlarged thyroid
      • UL: 1110 µg/day

    • Chromium:

      • Sources:

        • Brewers yeast, nuts, whole grains, mushrooms
      • Recommended intake for adults:

        • 25-35 µg/day 
      • Major functions:

        • Enhances insulin action
      • Deficiency diseases and symptoms:

        • High blood glucose 
    • Groups at risk of deficiency: 

    • Malnourished children  

    • Fluoride:

    • Sources:

      • Fluoridated water, tea, fish, toothpaste
    • Recommended daily intake for adults:

      • 3-4 mg/day
    • Major functions:

      • Strengthens tooth enamel, enhances remineralization of tooth enamel, reduces acid production by bacteria in the mouth
    • Deficiency diseases and symptoms:

      • Increased risk of dental caries 
    • Groups at risk of deficiency:

      • Populations in areas with unfluoridated water 
    • Toxicity:

      • Mottled teeth, kidney damage, bone abnormalities 
    • UL: 10 mg/day

    • Molybdenum:

      • Sources:

        • Milk, organ meats, grains, legumes
    • Recommended intake for adults:

      • 45 µg/day
    • Major functions:

      • Cofactor for a number of enzymes 
    • Toxicity:

      • Arthritis and joint pain
    • UL: 2 mg/day

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