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Questions and Answers
What do fat-soluble vitamins require for digestion and absorption?
What do fat-soluble vitamins require for digestion and absorption?
Which of the following is NOT a function of Vitamin A?
Which of the following is NOT a function of Vitamin A?
Where are excess fat-soluble vitamins primarily stored in the body?
Where are excess fat-soluble vitamins primarily stored in the body?
Which type of vitamin A is a precursor found in plant foods?
Which type of vitamin A is a precursor found in plant foods?
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What increases the risk of toxicity in fat-soluble vitamins?
What increases the risk of toxicity in fat-soluble vitamins?
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What is one of the roles of antioxidants related to free radicals?
What is one of the roles of antioxidants related to free radicals?
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Which of the following statements is TRUE regarding fat-soluble vitamins?
Which of the following statements is TRUE regarding fat-soluble vitamins?
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Which of the following is NOT a dietary form of Vitamin A?
Which of the following is NOT a dietary form of Vitamin A?
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What is the primary cause of vitamin K deficiency?
What is the primary cause of vitamin K deficiency?
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Which statement about vitamin K toxicity is correct?
Which statement about vitamin K toxicity is correct?
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What condition can lead to secondary deficiency of vitamin K?
What condition can lead to secondary deficiency of vitamin K?
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How is vitamin K primarily obtained in newborns?
How is vitamin K primarily obtained in newborns?
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Which statement about the synthesis of vitamin K is accurate?
Which statement about the synthesis of vitamin K is accurate?
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What is a significant consequence of vitamin A deficiency in developing countries?
What is a significant consequence of vitamin A deficiency in developing countries?
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Which symptoms are directly associated with vitamin A deficiency?
Which symptoms are directly associated with vitamin A deficiency?
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What is the role of vitamin A in reproduction and growth?
What is the role of vitamin A in reproduction and growth?
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What condition is primarily caused by vitamin A deficiency?
What condition is primarily caused by vitamin A deficiency?
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How does vitamin A toxicity commonly occur?
How does vitamin A toxicity commonly occur?
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Which population is most vulnerable to vitamin A toxicity?
Which population is most vulnerable to vitamin A toxicity?
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What is the function of retinol compared to carotenoids?
What is the function of retinol compared to carotenoids?
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What effect does overconsumption of beta-carotene from supplements have?
What effect does overconsumption of beta-carotene from supplements have?
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What crucial role does vitamin A play in the integrity of mucous membranes?
What crucial role does vitamin A play in the integrity of mucous membranes?
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Which of the following is NOT a role of vitamin A?
Which of the following is NOT a role of vitamin A?
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What are the two forms of vitamin D?
What are the two forms of vitamin D?
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What is the active form of vitamin D known as?
What is the active form of vitamin D known as?
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Which factor is NOT associated with an increased risk of vitamin D deficiency?
Which factor is NOT associated with an increased risk of vitamin D deficiency?
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What potential health issue is most likely caused by vitamin D deficiency?
What potential health issue is most likely caused by vitamin D deficiency?
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Which of the following is a common source of vitamin D?
Which of the following is a common source of vitamin D?
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What is a potential consequence of vitamin D toxicity?
What is a potential consequence of vitamin D toxicity?
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In addition to calcium, what other mineral absorption is assisted by vitamin D?
In addition to calcium, what other mineral absorption is assisted by vitamin D?
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What is a primary function of the active form of vitamin D?
What is a primary function of the active form of vitamin D?
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Which vitamin is most likely to have toxic effects when taken in excess?
Which vitamin is most likely to have toxic effects when taken in excess?
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What is the primary function of vitamin E in the body?
What is the primary function of vitamin E in the body?
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Which subgroup of vitamin E is predominantly maintained in the body?
Which subgroup of vitamin E is predominantly maintained in the body?
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What condition can vitamin E help prevent in premature infants?
What condition can vitamin E help prevent in premature infants?
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What is a common cause of secondary vitamin E deficiency?
What is a common cause of secondary vitamin E deficiency?
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Which of the following symptoms can result from vitamin E deficiency?
Which of the following symptoms can result from vitamin E deficiency?
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What is the tolerable upper intake level (UL) for vitamin E compared to the recommended dietary allowance (RDA) for adults?
What is the tolerable upper intake level (UL) for vitamin E compared to the recommended dietary allowance (RDA) for adults?
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What potential effect can extremely high doses of vitamin E have?
What potential effect can extremely high doses of vitamin E have?
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What happens to vitamin K in the body when exposed to light and alkalies?
What happens to vitamin K in the body when exposed to light and alkalies?
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Which food sources are commonly fortified with vitamin D?
Which food sources are commonly fortified with vitamin D?
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What is one key characteristic of vitamin E as noted in its absorption?
What is one key characteristic of vitamin E as noted in its absorption?
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Study Notes
Basics of Human Nutrition
- This is a course titled NUTR 202, part of the Department of Clinical Nutrition.
- The course covers fundamental aspects of human nutrition, particularly fat-soluble vitamins.
Fat-Soluble Vitamins
- Learning objectives include identifying vitamin types, functions, sources, and requirements.
- Students will also learn about symptoms and diseases associated with deficiencies of discussed vitamins.
Learning Objectives
- Students should be able to identify the types and functions of different vitamins.
- Students should know at least two sources of each vitamin.
- Understand the symptoms or diseases from vitamin deficiencies.
Introduction
- Fat-soluble vitamins differ from water-soluble vitamins.
- They require bile for digestion/absorption.
- They travel through the lymphatic system.
- Excesses are stored in adipose tissues.
- They are not readily excreted, increasing the risk of toxicity.
- The answer to the question about fat-soluble vitamins is given in the form of bullet points.
Antioxidants
- Antioxidants protect cells from free radicals.
- Free radicals have an unpaired number of electrons.
- These radicals form when oxygen interacts with molecules.
- These form reactive molecules which can damage cells like DNA and membranes.
- Antioxidants safely interact with free radicals, preventing cell damage.
Vitamin A
- Vitamin A consists of retinoids.
- Retinoids include retinol, retinal, retinoic acid and retinyl esters.
- Functions include critical roles in vision, bone growth, reproduction, cell division, regulation of the immune system, and antioxidant activity.
- A vitamin A precursor is Beta-carotene.
- Animal forms of vitamin A are more effective than plant forms.
- Vitamin A's role in vision involves light converting to electrical impulses.
- The retina cells contain rhodopsin (a protein+retinal).
- Light changes cis-retinal to trans-retinal which sends electrical signals to the brain.
- Vitamin A's role in maintaining mucous membrane integrity is critical for healthy cells.
- Reproduction and growth are also important functions of vitamin A.
- It is important for sperm development, normal fetal development and growth.
- Crucial for bone remodeling, too.
- Vitamin A deficiency is prevalent in developing countries.
- Deficiency can lead to increased risk of infectious diseases, causing night blindness/blindness (xerophthalmia).
- Keratinization is a characteristic symptom when vitamin A is deficient.
- This can block hair follicles causing white lumps or hyperkeratosis.
- Vitamin A toxicity is possible with concentrated amounts from supplements.
- It can damage cells, especially with high intakes.
- Children are most vulnerable to this.
- Vitamin A toxicity can lead to bone and birth defects.
Vitamin D
- Vitamin D exists in two forms: cholecalciferol (animal) and ergocalciferol (plant).
- Both forms need activation before functioning fully.
- The active form of vitamin D is 1,25-dihydroxycholecalciferol.
- Vitamin D is stable and not easily oxidized.
- It's not affected by storage, or processing of food.
- Vitamin D is a hormone essential to making/maintaining bones.
- It aids in the absorption of calcium and phosphorus.
- Protects against cognitive decline in brain and nerve cells.
- Vitamin D deficiency can be from dark skin, lack of breastfeeding, lack of sunlight exposure, or low consumption of fortified milk.
- The likely deficiency associated with lack of Vitamin D is Calcium.
- Rickets is a symptom of vitamin D deficiency.
- This may cause bowed legs and beaded ribs.
- Vitamin D toxicity is rare.
- Excess amounts via supplements are dangerous.
- Excess can raise blood calcium levels and form stones in soft tissues.
- Excess vitamin D can harden vessels and lead to death.
- The best sources of vitamin D are sunlight exposure, animal products (fatty fish and beef liver), and small amounts in dairy products.
Vitamin E
- Vitamin E has two subgroups: tocopherols and tocotrienols.
- Only alpha-tocopherol remains in the body.
- Its main function is an antioxidant.
- It is aided by vitamin C and selenium.
- Transported in blood by lipoproteins.
- It prevents hemolytic anemia in premature infants.
- Its antioxidant properties are used commercially to prevent food spoilage.
- Primary deficiency is rare. Secondary may be from fat malabsorption (like cystic fibrosis).
- Deficiency can lead to splitting of red blood cells due to oxidized PUFAs—leading to anemia, neuromuscular dysfunction.
- Muscle coordination, reflex effects, vision can be impaired.
- Vitamin E Toxicity is rare. But high doses can interfere with vitamin K blood-clotting activity
- Liver regulates Vitamin E levels.
- The most significant sources are vegetable oils, seeds and nuts.
Vitamin K
- Vitamin K consists of several compounds crucial for blood clotting.
- It is destroyed by light and alkalis.
- Absorbed from the small and slightly larger intestine—needs bile from the liver and fats in the diet.
- Newborns are given a dose by intramuscular injection.
- The blood-clotting process depends on several factors that use vitamin K.
- Primary vitamin K deficiency is rare. Secondary can be from antibiotic use or bile production issues in the liver, sterilizing the gut
- Insufficient dietary intake, or antibiotic use can lead to a deficiency.
- Babies have sterile guts, so vitamin K is often given at birth due to this.
- Vitamin K toxicity is not common and generally doesn't have adverse effects with high intakes, there is no UL.
- High doses potentially reduce the effectiveness of blood thinners.
- Good sources of vitamin K are green vegetables (collards, spinach, cabbage).
- There is also vitamin K in vegetable oils like soybean and canola oils.
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Description
Test your knowledge on fat-soluble vitamins in the NUTR 202 course. This quiz covers types, functions, sources, and deficiency symptoms of these essential nutrients. Perfect for students wanting to reinforce their understanding of human nutrition.