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Questions and Answers
Which term collectively refers to the processes of absorption, distribution, metabolism, and elimination of drug substances in the body?
In which administration route do drug substances bypass the need to move into the systemic circulation, as mentioned in the text?
Which drug substance tends to stay within the systemic circulation, as indicated in the text?
Which type of drug substances do not get metabolized because they are not substrates of metabolizing enzymes in the body?
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Which drug substance never gets absorbed from the gastrointestinal system after oral administration?
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How do dissolved drug particles cross an epithelium?
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Which process requires energy and occurs against the concentration gradient?
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What factor affects the rate of diffusion by permeability and concentration difference?
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What does the term 'pharmacokinetics' refer to?
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Which of the following is NOT a part of PK actions?
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What is the main function of distribution in pharmacokinetics?
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Which type of drug substances undergo movement into the systemic circulation during absorption?
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What role does metabolism play in pharmacokinetics?
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Which factor affects the rate of diffusion by permeability and concentration difference in pharmacokinetics?
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What does pharmacokinetics (PK) study?
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Which of the following is NOT included in the PK actions of drug substances?
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What is distribution in pharmacokinetics (PK)?
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What does pharmacodynamics (PD) study?
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Which of the following is NOT a type of pharmacokinetic action?
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What is elimination in pharmacokinetics (PK)?
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What is the term used to describe the concept of the drug's ability to produce a maximum response at a specific dose?
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In pharmacodynamics, which type of inhibition occurs when the inhibitor binds to a different site other than the active site of the enzyme?
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What is the term for the region of an enzyme where the substrate binds and the chemical reaction takes place?
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Which term describes the phenomenon where two or more drugs interact with each other to produce an effect that is greater than the sum of their individual effects?
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What is the term for the ability of a drug to bind to a receptor and produce a biological response?
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Which factor affects the binding of a substrate to a protein by changing the protein's conformation and reducing its activity?
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What is the main function of insulin?
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What happens when proteins denature at extreme pH or temperature?
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What is the lock-and-key hypothesis used to describe?
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What is an effect of the locked key being opened in the lock-key complex analogy?
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What is the effect of substrate binding that is related to molecular polarity?
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What are substrates that bind to the active site classified as?
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What is the main function of distribution in pharmacokinetics?
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What is the role of metabolism in pharmacokinetics (PK)?
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What factor affects the rate of diffusion by permeability and concentration difference?
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What type of substances undergo movement into the systemic circulation during absorption?
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