Nucleotides: Structure, Functions, and Disorders
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Questions and Answers

What is the primary function of nucleotides in all cells?

  • Function as structural components of lipids
  • Act as building blocks for proteins
  • Are the main storage form of genetic information
  • Serve as metabolic regulators (correct)

Which of the following is true regarding nucleotide derivatives?

  • They are not involved in biosynthetic processes
  • They primarily function as enzymes
  • They serve as the structural components of cell membranes
  • They are activated intermediates in biosynthetic processes (correct)

What is a consequence of defects in nucleotide metabolism?

  • Decreased risk of human disorders
  • Increased production of ATP
  • Association with some human disorders (correct)
  • Enhanced cell signaling activation

How do several drugs used to treat cancer and bacterial infections typically function?

<p>At the level of nucleotide metabolism (B)</p> Signup and view all the answers

Which nucleotide serves as the major currency of energy in all cells?

<p>ATP (B)</p> Signup and view all the answers

What term is used to describe the group of three nucleotides that encode an amino acid in the genetic code?

<p>Codons (A)</p> Signup and view all the answers

Which term best describes the degeneracy of the genetic code?

<p>Some amino acids have more than one codon (B)</p> Signup and view all the answers

What is typically discarded during RNA processing?

<p>Introns (D)</p> Signup and view all the answers

In the genetic code, what do codons represent?

<p>Amino acids (C)</p> Signup and view all the answers

What is the direction in which codons are read by the translation machinery?

<p>5' to 3' (D)</p> Signup and view all the answers

What aspect of the genetic code ensures that each triplet specifies only one amino acid?

<p>Unambiguity (B)</p> Signup and view all the answers

What amino acid replaces glutamic acid in the HbS molecule found in sickle cell anemia?

<p>Valine (D)</p> Signup and view all the answers

In sickle-cell disease, which nucleotide change can lead to the production of an abnormal protein?

<p>Adenine to thymine (A)</p> Signup and view all the answers

The AB blood type is an example of what genetic phenomenon?

<p>Codominance (D)</p> Signup and view all the answers

Which genetic concept is exemplified when both alleles for A and B blood groups are dominant to the i allele?

<p>Codominance (A)</p> Signup and view all the answers

What genetic term describes a scenario where one gene affects multiple phenotypic characters?

<p>Pleiotropy (D)</p> Signup and view all the answers

Which blood type combination showcases two non-identical alleles that are both displayed?

<p>(IAIB) (D)</p> Signup and view all the answers

Which statement best describes the structure of a tRNA molecule?

<p>A tRNA molecule looks like a cloverleaf when flattened into one plane due to base pairing. (B)</p> Signup and view all the answers

What is the role of hydrogen bonds in the structure of tRNA?

<p>Hydrogen bonds help tRNA twist and fold into a three-dimensional molecule. (D)</p> Signup and view all the answers

What is the significance of the wobble hypothesis in genetic translation?

<p>The wobble hypothesis states that base pairing rules are relaxed at the third position of the codon. (C)</p> Signup and view all the answers

In the context of the wobble hypothesis, what is meant by 'wobble'?

<p>'Wobble' describes the flexibility in base pairing at the third position of the codon. (A)</p> Signup and view all the answers

Why is the third position of a codon particularly important according to the wobble hypothesis?

<p>The third position allows for redundancy in codons coding for the same amino acid due to wobble. (B)</p> Signup and view all the answers

What distinguishes tRNA from other RNA molecules based on its structure?

<p>tRNA forms a cloverleaf shape when flattened, unlike other RNA molecules. (C)</p> Signup and view all the answers

In the context of genetics, what does the term 'norm of reaction' refer to?

<p>The phenotypic range of a genotype influenced by the environment (B)</p> Signup and view all the answers

Why do hydrangea flowers of the same genotype range from blue-violet to pink?

<p>Depending on soil acidity (B)</p> Signup and view all the answers

What type of characters exhibit broad norms of reaction and are influenced by both genetic and environmental factors?

<p>Polygenic characters (D)</p> Signup and view all the answers

If unattached earlobes are dominant to attached earlobes, what is the probability that two parents with unattached earlobes will have a child with attached earlobes?

<p>0% (C)</p> Signup and view all the answers

Based on the pedigree provided, what inheritance pattern does Duchenne Muscular Dystrophy (DMD) follow?

<p>X-linked recessive disorder (D)</p> Signup and view all the answers

What is the name of the gene located on the Y chromosome that encodes the proteins determining maleness?

<p>SRY gene (C)</p> Signup and view all the answers

What is the genetic basis of Down Syndrome?

<p>Extra copy of chromosome 21 (C)</p> Signup and view all the answers

Which condition results from an extra X chromosome in males?

<p>Klinefelter syndrome (B)</p> Signup and view all the answers

What is a characteristic feature of Turner syndrome individuals?

<p>Fertility in females (C)</p> Signup and view all the answers

Which syndrome results from a specific deletion in chromosome 5?

<p>Cri du chat syndrome (D)</p> Signup and view all the answers

What is the correlation between maternal age and the frequency of Down syndrome?

<p>Frequency increases with maternal age (A)</p> Signup and view all the answers

Which condition is caused by a missing chromosome in females?

<p>Monosomy X (B)</p> Signup and view all the answers

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