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Questions and Answers
What is the size of the nuclear pore complex compared to a ribosome?
How do molecules up to 40-60 kDa move through the NPC?
What type of interactions do FG nucleoporins possess?
What is the function of a nuclear localization signal (NLS) in proteins?
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What is the function of Ran in nuclear import?
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Study Notes
Nuclear Pore Complex and Ribosome Size Comparison
- The nuclear pore complex is approximately 120 nm in diameter, while a ribosome is around 20-30 nm in diameter, making the NPC significantly larger.
Molecular Transport through Nuclear Pore Complex
- Molecules up to 40-60 kDa can move through the nuclear pore complex (NPC) via facilitated diffusion or passive transport.
FG Nucleoporins
- FG nucleoporins possess hydrophobic and hydrophilic interactions, which facilitate molecular transport through the nuclear pore complex.
Nuclear Localization Signal (NLS)
- A nuclear localization signal (NLS) is a specific amino acid sequence in proteins that helps them target and enter the nucleus.
Ran and Nuclear Import
- Ran, a GTPase, plays a crucial role in nuclear import by facilitating the transport of macromolecules into the nucleus.
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Description
Test your knowledge of nucleo-cytoplasmic transport with this quiz from McGill BIOL200 - Fall 2023. Explore the structure and function of the nuclear pore complex, its role in nucleocytoplasmic transport, and its composition. Sharpen your understanding of this essential process for cellular function.
