Non-insulin Injectable Antidiabetics Quiz
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Questions and Answers

What is the expected pharmacological action of Amylin mimetics like Pramlintide?

  • Increase gastric emptying time and promote glucagon secretion
  • Inhibit gastric emptying time and inhibit glucagon secretion
  • Increase gastric emptying time and inhibit glucagon secretion
  • Decrease gastric emptying time and inhibit glucagon secretion (correct)
  • Which statement is true regarding the therapeutic uses of Amylin mimetics?

  • Used as supplemental glucose control for both type 1 and type 2 diabetes mellitus (correct)
  • Can be used alone without any other antidiabetic medication
  • Primarily used for type 2 diabetes only
  • Given to clients with effective glucose control using insulin therapy
  • How do Incretin mimetics like Exenatide affect appetite?

  • Decrease appetite (correct)
  • Promote weight gain
  • Have no effect on appetite
  • Increase appetite
  • Which of the following statements is true about Incretin mimetics?

    <p>Promotes release of insulin and lowers blood glucose levels</p> Signup and view all the answers

    What complication is commonly associated with Amylin mimetics?

    <p>Nausea</p> Signup and view all the answers

    In what way does Pramlintide affect caloric intake?

    <p>Decreases caloric intake</p> Signup and view all the answers

    When should Incretin mimetics typically be used in diabetic therapy?

    <p>In combination with oral antidiabetic medications</p> Signup and view all the answers

    What is the primary purpose of Incretin mimetics like Exenatide?

    <p>Decrease blood glucose levels</p> Signup and view all the answers

    For which clients are Amylin mimetics typically considered for supplemental glucose control?

    <p>Clients with uncontrolled type 2 diabetes</p> Signup and view all the answers

    What actions do Incretin mimetics have on gastric emptying?

    <p>Slows down gastric emptying</p> Signup and view all the answers

    What is a major contraindication for amylin mimetics?

    <p>Kidney failure</p> Signup and view all the answers

    How should oral medications be administered in relation to exenatide (incretin mimetic) injections?

    <p>Administer oral medications 1 hour before exenatide injections</p> Signup and view all the answers

    When should the provider decrease the client’s premeal insulin dose by 50% when starting pramlintide therapy?

    <p>Pre-breakfast</p> Signup and view all the answers

    What is one clinical manifestation that should prompt the client to notify the provider immediately?

    <p>Intolerable abdominal pain</p> Signup and view all the answers

    What is a significant risk of concurrent use of insulin and amylin mimetics?

    <p>Hypoglycemia</p> Signup and view all the answers

    Why should amylin mimetics be avoided in clients unable to self-monitor blood glucose levels?

    <p>Potential increased risk of hypoglycemia</p> Signup and view all the answers

    What part of the body is the recommended injection site for amylin mimetics?

    <p>Abdomen</p> Signup and view all the answers

    Why should subcutaneous injections of amylin mimetics be at least 5cm (2 in) from an insulin injection site?

    <p>To prevent alteration of insulin absorption</p> Signup and view all the answers

    In what situation should the oral medication absorption not be delayed in relation to pramlintide injections?

    <p>With oral contraceptives</p> Signup and view all the answers

    How can the effectiveness of incretin mimetics be evidenced based on therapeutic intent?

    <p>Low preprandial glucose levels</p> Signup and view all the answers

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