Non-insulin Injectable Antidiabetics Quiz

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What is the expected pharmacological action of Amylin mimetics like Pramlintide?

Increase gastric emptying time and promote glucagon secretion

Inhibit gastric emptying time and inhibit glucagon secretion

Increase gastric emptying time and inhibit glucagon secretion

Decrease gastric emptying time and inhibit glucagon secretion (correct)

Which statement is true regarding the therapeutic uses of Amylin mimetics?

Used as supplemental glucose control for both type 1 and type 2 diabetes mellitus (correct)

Can be used alone without any other antidiabetic medication

Primarily used for type 2 diabetes only

Given to clients with effective glucose control using insulin therapy

How do Incretin mimetics like Exenatide affect appetite?

Decrease appetite (correct)

Promote weight gain

Have no effect on appetite

Increase appetite

Which of the following statements is true about Incretin mimetics?

Promotes release of insulin and lowers blood glucose levels Signup and view all the answers

What complication is commonly associated with Amylin mimetics?

Nausea Signup and view all the answers

In what way does Pramlintide affect caloric intake?

Decreases caloric intake Signup and view all the answers

When should Incretin mimetics typically be used in diabetic therapy?

In combination with oral antidiabetic medications Signup and view all the answers

What is the primary purpose of Incretin mimetics like Exenatide?

Decrease blood glucose levels Signup and view all the answers

For which clients are Amylin mimetics typically considered for supplemental glucose control?

Clients with uncontrolled type 2 diabetes Signup and view all the answers

What actions do Incretin mimetics have on gastric emptying?

Slows down gastric emptying Signup and view all the answers

What is a major contraindication for amylin mimetics?

Kidney failure Signup and view all the answers

How should oral medications be administered in relation to exenatide (incretin mimetic) injections?

Administer oral medications 1 hour before exenatide injections Signup and view all the answers

When should the provider decrease the client’s premeal insulin dose by 50% when starting pramlintide therapy?

Pre-breakfast Signup and view all the answers

What is one clinical manifestation that should prompt the client to notify the provider immediately?

Intolerable abdominal pain Signup and view all the answers

What is a significant risk of concurrent use of insulin and amylin mimetics?

Hypoglycemia Signup and view all the answers

Why should amylin mimetics be avoided in clients unable to self-monitor blood glucose levels?

Potential increased risk of hypoglycemia Signup and view all the answers

What part of the body is the recommended injection site for amylin mimetics?

Abdomen Signup and view all the answers

Why should subcutaneous injections of amylin mimetics be at least 5cm (2 in) from an insulin injection site?

To prevent alteration of insulin absorption Signup and view all the answers

In what situation should the oral medication absorption not be delayed in relation to pramlintide injections?

With oral contraceptives Signup and view all the answers

How can the effectiveness of incretin mimetics be evidenced based on therapeutic intent?

Low preprandial glucose levels Signup and view all the answers