Non-insulin Injectable Antidiabetics Quiz

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Questions and Answers

What is the expected pharmacological action of Amylin mimetics like Pramlintide?

  • Increase gastric emptying time and promote glucagon secretion
  • Inhibit gastric emptying time and inhibit glucagon secretion
  • Increase gastric emptying time and inhibit glucagon secretion
  • Decrease gastric emptying time and inhibit glucagon secretion (correct)

Which statement is true regarding the therapeutic uses of Amylin mimetics?

  • Used as supplemental glucose control for both type 1 and type 2 diabetes mellitus (correct)
  • Can be used alone without any other antidiabetic medication
  • Primarily used for type 2 diabetes only
  • Given to clients with effective glucose control using insulin therapy

How do Incretin mimetics like Exenatide affect appetite?

  • Decrease appetite (correct)
  • Promote weight gain
  • Have no effect on appetite
  • Increase appetite

Which of the following statements is true about Incretin mimetics?

<p>Promotes release of insulin and lowers blood glucose levels (D)</p> Signup and view all the answers

What complication is commonly associated with Amylin mimetics?

<p>Nausea (B)</p> Signup and view all the answers

In what way does Pramlintide affect caloric intake?

<p>Decreases caloric intake (B)</p> Signup and view all the answers

When should Incretin mimetics typically be used in diabetic therapy?

<p>In combination with oral antidiabetic medications (B)</p> Signup and view all the answers

What is the primary purpose of Incretin mimetics like Exenatide?

<p>Decrease blood glucose levels (A)</p> Signup and view all the answers

For which clients are Amylin mimetics typically considered for supplemental glucose control?

<p>Clients with uncontrolled type 2 diabetes (A)</p> Signup and view all the answers

What actions do Incretin mimetics have on gastric emptying?

<p>Slows down gastric emptying (C)</p> Signup and view all the answers

What is a major contraindication for amylin mimetics?

<p>Kidney failure (D)</p> Signup and view all the answers

How should oral medications be administered in relation to exenatide (incretin mimetic) injections?

<p>Administer oral medications 1 hour before exenatide injections (B)</p> Signup and view all the answers

When should the provider decrease the client’s premeal insulin dose by 50% when starting pramlintide therapy?

<p>Pre-breakfast (D)</p> Signup and view all the answers

What is one clinical manifestation that should prompt the client to notify the provider immediately?

<p>Intolerable abdominal pain (B)</p> Signup and view all the answers

What is a significant risk of concurrent use of insulin and amylin mimetics?

<p>Hypoglycemia (C)</p> Signup and view all the answers

Why should amylin mimetics be avoided in clients unable to self-monitor blood glucose levels?

<p>Potential increased risk of hypoglycemia (D)</p> Signup and view all the answers

What part of the body is the recommended injection site for amylin mimetics?

<p>Abdomen (D)</p> Signup and view all the answers

Why should subcutaneous injections of amylin mimetics be at least 5cm (2 in) from an insulin injection site?

<p>To prevent alteration of insulin absorption (D)</p> Signup and view all the answers

In what situation should the oral medication absorption not be delayed in relation to pramlintide injections?

<p>With oral contraceptives (A)</p> Signup and view all the answers

How can the effectiveness of incretin mimetics be evidenced based on therapeutic intent?

<p>Low preprandial glucose levels (C)</p> Signup and view all the answers

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