Questions and Answers
What is the therapeutic class of Insulin Aspart?
What is the pharmaceutical class of Insulin Aspart?
Pancreatics
What are the indications for using Insulin Aspart?
Control of hyperglycemia in patients with type 1 or type 2 diabetes mellitus.
How does Insulin Aspart lower blood glucose?
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The onset, peak, and duration of Insulin Aspart are ______.
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Which of the following are contraindications for Insulin Aspart?
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When should Insulin Aspart be used with caution?
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Study Notes
Therapeutic and Pharmaceutical Classes
- Classified as antidiabetics and hormones.
- Falls under the pharmaceutical class of pancreatic medications.
Indications
- Used for controlling hyperglycemia in both type 1 and type 2 diabetes mellitus patients.
Mechanism of Action
- Lowers blood glucose levels by:
- Stimulating glucose uptake in skeletal muscle and adipose tissue.
- Inhibiting hepatic glucose production.
- Also inhibits lipolysis and proteolysis while enhancing protein synthesis.
- Considered a rapid-acting insulin with a quicker onset and shorter duration compared to human regular insulin.
- Should be administered alongside intermediate or long-acting insulin for effective results.
Pharmacokinetics
- Onset of action: approximately 15 minutes.
- Peak effect: reached in about 1 hour.
- Duration of action: lasts for approximately 3 hours.
Contraindications and Precautions
- Contraindicated in cases of:
- Hypoglycemia.
- Allergy or hypersensitivity to insulin aspart.
- Cautiously used in patients experiencing:
- Stress and infections, which can increase insulin requirements.
- Renal or hepatic impairment, possibly decreasing insulin needs.
- Must always be combined with a longer-acting insulin for type 1 diabetes management.
- Risk of worsened heart failure and fluid retention when used alongside pioglitazone or rosiglitazone.
- Pregnant patients may experience increased insulin needs temporarily.
- Special consideration is given to pediatric patients.
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Description
This quiz focuses on key concepts related to Insulin Aspart, including its therapeutic and pharmaceutical classes, indications, and action mechanism. Ideal for medical students and healthcare professionals who want to enhance their understanding of diabetes management.