Podcast
Questions and Answers
What is the most common site for ulcerative PG to develop?
What is the most common site for ulcerative PG to develop?
- Back
- Arm
- Abdomen
- Leg (correct)
Which of the following is a characteristic feature of ulcerative PG?
Which of the following is a characteristic feature of ulcerative PG?
- Purulent necrotic material at the base (correct)
- Base covered with clear fluid
- Surrounding zone of cyanosis
- Central elevation of skin
What distinguishes Bullous PG from the most common variant of PG?
What distinguishes Bullous PG from the most common variant of PG?
- Appearance as a furuncle
- Associated with hematologic disease (correct)
- Development on the chest
- Presence of painless blisters
What characterizes the development of Bullous PG?
What characterizes the development of Bullous PG?
What phenomenon describes the induction of exaggerated flaring of PG at the site of trauma or surgery?
What phenomenon describes the induction of exaggerated flaring of PG at the site of trauma or surgery?
Which of the following best describes the classic ulcerative variant of Pyoderma gangrenosum?
Which of the following best describes the classic ulcerative variant of Pyoderma gangrenosum?
What is a common characteristic of Pyoderma gangrenosum ulcers during the healing process?
What is a common characteristic of Pyoderma gangrenosum ulcers during the healing process?
What is a distinguishing feature of Pyoderma gangrenosum in relation to trauma?
What is a distinguishing feature of Pyoderma gangrenosum in relation to trauma?
How is Pyoderma gangrenosum believed to be associated with other conditions?
How is Pyoderma gangrenosum believed to be associated with other conditions?
What is the estimated incidence of Pyoderma gangrenosum cases per million people per year?
What is the estimated incidence of Pyoderma gangrenosum cases per million people per year?
At what age range do most Pyoderma gangrenosum cases occur?
At what age range do most Pyoderma gangrenosum cases occur?
What is a recommended approach for the diagnosis of Pyoderma Gangrenosum (PG)?
What is a recommended approach for the diagnosis of Pyoderma Gangrenosum (PG)?
Which of the following is NOT mentioned as a potential non-cutaneous finding associated with PG?
Which of the following is NOT mentioned as a potential non-cutaneous finding associated with PG?
What is a potential consequence of poorly controlled cutaneous PG?
What is a potential consequence of poorly controlled cutaneous PG?
Which side effect is specifically mentioned for corticosteroid therapy in the context of PG treatment?
Which side effect is specifically mentioned for corticosteroid therapy in the context of PG treatment?
Why should elective surgery be approached cautiously in patients with PG?
Why should elective surgery be approached cautiously in patients with PG?
What can be a consequence of failing to recognize neutrophilic infiltration in internal organs in PG?
What can be a consequence of failing to recognize neutrophilic infiltration in internal organs in PG?
What factors are likely to contribute to the etiology of PG?
What factors are likely to contribute to the etiology of PG?
How does resection of diseased bowel affect PG skin healing?
How does resection of diseased bowel affect PG skin healing?
What improvement has been observed in bullous PG after treatment of acute myeloid leukemia?
What improvement has been observed in bullous PG after treatment of acute myeloid leukemia?
Which cells are suggested to be important in the development of PG according to the text?
Which cells are suggested to be important in the development of PG according to the text?
What is postulated to occur due to the presence of a lymphocytic infiltrate at the active advancing border of PG lesions?
What is postulated to occur due to the presence of a lymphocytic infiltrate at the active advancing border of PG lesions?
Which inflammatory mediator is mentioned as a potent neutrophil chemotactic agent?
Which inflammatory mediator is mentioned as a potent neutrophil chemotactic agent?
Which tissue, other than the skin, is mentioned as a location where neutrophils are present?
Which tissue, other than the skin, is mentioned as a location where neutrophils are present?
Which proinflammatory cytokine is NOT mentioned as being produced by TNF-α?
Which proinflammatory cytokine is NOT mentioned as being produced by TNF-α?
What is the genetic disorder associated with mutations in the PSTPIP1 gene?
What is the genetic disorder associated with mutations in the PSTPIP1 gene?
What does PAPASH syndrome include, along with pyogenic sterile arthritis and PG?
What does PAPASH syndrome include, along with pyogenic sterile arthritis and PG?
Which syndrome results from an increased CCTG microsatellite repeat in the promoter region of the PSTPIP1 gene?
Which syndrome results from an increased CCTG microsatellite repeat in the promoter region of the PSTPIP1 gene?
What is the function of PSTPIP1 in relation to pyrin and the inflammasome?
What is the function of PSTPIP1 in relation to pyrin and the inflammasome?
