Nitrofurantoin (Macrobid) Flashcards

Questions and Answers

What is the brand name of Nitrofurantoin?

Nitrofurantoin

Macrobid (correct)

Antibiotic

UTI

What is the generic name of Macrobid?

Nitrofurantoin

What is the drug class of Nitrofurantoin (Macrobid)?

Nitrofuran Antibiotic

Approved indications for Nitrofurantoin (Macrobid) include ______.

UTI, treatment; UTI, prophylaxis Signup and view all the answers

What is a contraindication for Nitrofurantoin (Macrobid)?

Hypersensitivity to nitrofurantoin, use in neonates of pregnant patients at term (38-42 weeks) due to risk of hemolytic anemia, anuria or oliguria Signup and view all the answers

What are common adverse reactions for Nitrofurantoin (Macrobid)?

Nausea, Headache, Discoloration of urine Signup and view all the answers

Nitrofurantoin (Macrobid) has a black box warning.

False Signup and view all the answers

What are the monitoring parameters for Nitrofurantoin (Macrobid)?

Efficacy: Resolution of clinical signs of infection within 2-3 days. Toxicity: Severe diarrhea, yellowing of skin or eye, unusual bruising or bleeding, blistering skin rash, or shortness of breath. Signs of pulmonary reaction, numbness or tingling of extremities. With long-term use, CBC, LFTs, SCr. Signup and view all the answers

Study Notes

Nitrofurantoin (Macrobid) Overview

Nitrofurantoin's brand name is Macrobid.
The generic name for Macrobid is nitrofurantoin.
Nitrofurantoin belongs to the class of nitrofuran antibiotics.

Approved Uses

Primarily indicated for the treatment of urinary tract infections (UTIs).
Also used for UTI prophylaxis.

Contraindications

Not to be used in individuals with hypersensitivity to nitrofurantoin.
Contraindicated in neonates born to pregnant patients at term (38-42 weeks) due to the risk of hemolytic anemia.
Should not be administered in cases of anuria or oliguria.

Common Side Effects

May cause nausea and headache.
Can lead to urine discoloration, which is a recognized side effect.

Black Box Warnings

Nitrofurantoin does not carry any black box warnings.

Monitoring Parameters

Efficacy should be assessed by the resolution of clinical signs of infection within 2-3 days.
Monitor for signs of toxicity including severe diarrhea, jaundice, unusual bruising or bleeding, blistering skin rash, or shortness of breath.
Be aware of potential pulmonary reactions and symptoms such as numbness or tingling in extremities.
With long-term use, it's important to monitor complete blood count (CBC), liver function tests (LFTs), and serum creatinine (SCr).

Description

Test your knowledge on Nitrofurantoin, commonly known as Macrobid, through these flashcards. Explore important information including its generic name, drug class, approved indications, and contraindications. Perfect for students studying pharmacology or healthcare providers.