Nitrofurantoin (Macrobid) Flashcards

Study Notes

Nitrofurantoin (Macrobid) Overview

Nitrofurantoin's brand name is Macrobid.
The generic name for Macrobid is nitrofurantoin.
Nitrofurantoin belongs to the class of nitrofuran antibiotics.

Approved Uses

Primarily indicated for the treatment of urinary tract infections (UTIs).
Also used for UTI prophylaxis.

Contraindications

Not to be used in individuals with hypersensitivity to nitrofurantoin.
Contraindicated in neonates born to pregnant patients at term (38-42 weeks) due to the risk of hemolytic anemia.
Should not be administered in cases of anuria or oliguria.

Common Side Effects

May cause nausea and headache.
Can lead to urine discoloration, which is a recognized side effect.

Black Box Warnings

Nitrofurantoin does not carry any black box warnings.

Monitoring Parameters

Efficacy should be assessed by the resolution of clinical signs of infection within 2-3 days.
Monitor for signs of toxicity including severe diarrhea, jaundice, unusual bruising or bleeding, blistering skin rash, or shortness of breath.
Be aware of potential pulmonary reactions and symptoms such as numbness or tingling in extremities.
With long-term use, it's important to monitor complete blood count (CBC), liver function tests (LFTs), and serum creatinine (SCr).

Description

Test your knowledge on Nitrofurantoin, commonly known as Macrobid, through these flashcards. Explore important information including its generic name, drug class, approved indications, and contraindications. Perfect for students studying pharmacology or healthcare providers.