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Questions and Answers
What is the action of Nitrofurantoin?
What is the action of Nitrofurantoin?
- Inhibits bacterial cell wall formation (correct)
- Used only for chronic UTIs
- Treats gram + and gram - (correct)
- Inhibits bacterial enzymes and metabolism (correct)
What is the general information regarding Nitrofurantoin?
What is the general information regarding Nitrofurantoin?
Is bacteriostatic or bactericidal depending on dosage, especially effective against E.coli.
What is the drug class of Nitrofurantoin?
What is the drug class of Nitrofurantoin?
Urinary antiinfective
Which of the following are side effects or adverse reactions of Nitrofurantoin? (Select all that apply)
Which of the following are side effects or adverse reactions of Nitrofurantoin? (Select all that apply)
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What are some nursing interventions for Nitrofurantoin?
What are some nursing interventions for Nitrofurantoin?
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Study Notes
Nitrofurantoin Overview
- Nitrofurantoin (Macrodantin) is an antibiotic effective against both gram-positive and gram-negative bacteria.
- Inhibits bacterial enzymes and metabolism, impairing cell wall formation, making it effective for treating acute and chronic urinary tract infections (UTIs).
General Information
- Functions as either bacteriostatic or bactericidal based on the dosage administered.
- Particularly effective against E. coli, a common cause of UTIs.
Drug Classification
- Classified as a urinary antiinfective agent, specifically designed to combat infections in the urinary system.
Side Effects and Adverse Reactions
- Common side effects include dizziness, headache (HA), drowsiness, and GI distress.
- Notable adverse reactions include:
- Rust-colored or brown urine
- Rash and pruritus (itching)
- Risk of superinfection
- Peripheral neuropathy
- Hepatotoxicity (liver damage)
- Stevens-Johnson syndrome (a severe skin reaction)
- Blood dyscrasias (abnormal blood counts)
Nursing Interventions
- Administer with food to minimize gastrointestinal distress.
- Antacids should be avoided as they can interfere with absorption.
- Capsules should not be crushed or opened to maintain drug efficacy.
- Shake liquid suspension well before use and rinse mouth afterward to prevent staining.
- Caution advised: do not drive or operate heavy machinery due to potential drowsiness.
- Encourage increased fluid intake and the consumption of cranberry juice, plums, proteins, and vitamin C to help in preventing UTIs.
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