Questions and Answers
What is the primary mechanism of action of Niacin (Vitamin B3) in decreasing liver triglyceride and VLDL synthesis?
Increasing activity of DGAT2 to decrease liver triglyceride synthesis
Why is Niacin dosing recommended twice or thrice daily?
To maintain a consistent level of Niacin in the bloodstream
What is the significant drug-drug interaction (DDI) associated with Niacin and statins?
Elevated myotoxicity
