Questions and Answers
What is Niacin classified as?
What is the therapeutic class of Niacin?
Antilipemic Drug (lipid lowering agent)
What is a primary action of Niacin?
Which of the following increases the risk for myopathy when taking Niacin?
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Which condition is a contraindication for Niacin?
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Aspirin should be taken 30 minutes before each dose of Niacin to reduce side effects.
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What are some common side effects of Niacin?
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Niacin monitoring includes blood glucose, liver function tests, and ______.
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Study Notes
Niacin (Nicotinic Acid, Vitamin B3)
- Water-soluble vitamin important for various bodily functions.
- Therapeutic class as an antilipemic drug, useful in lowering lipid levels.
- Classified as Pregnancy Category C, indicating potential risks during pregnancy.
Actions and Uses
- Decreases LDL cholesterol and triglyceride levels.
- Beneficial for patients at risk for pancreatitis and high triglyceride levels.
- Used for treating and preventing niacin deficiency (pellagra).
- Large doses can inhibit the release of free fatty acids from adipose tissue.
Interactions
- Increased risk of myopathy when used in combination with statins.
Contraindications
- Not recommended for individuals with hypertension, peptic ulcer disease, liver disease, active bleeding, or gout.
Administration Considerations
- Administered orally; large doses are necessary for lipid-lowering effects and cannot typically be achieved with over-the-counter supplements.
- Pre-medication with aspirin or NSAIDs 30 minutes prior helps mitigate side effects like flushing.
Side/Adverse Effects
- Common side effects include gastrointestinal distress, facial flushing, pruritis (itching), rash, and temporary tingling sensations in hands and feet.
- Severe adverse effects can include hepatotoxicity and hyperuricemia.
Nursing Considerations
- Monitor blood glucose levels during treatment.
- Establish baseline liver function tests and continue monitoring liver and kidney functions regularly.
- Keep track of blood urea nitrogen (BUN), creatinine, and input/output (I&O) levels.
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Description
Test your knowledge of Niacin, also known as nicotinic acid or vitamin B3, through these informative flashcards. Learn about its pharmacological class, therapeutic uses, and its role in managing cholesterol levels. Perfect for students and professionals in the health sciences field.
