40 Questions
Niacin is also known as __________ acid.
False
Niacin is a vitamer of vitamin ___.
False
Niacin is produced by plants and animals from the amino acid __________.
False
Niacin's role in the cure of pellagra was discovered in the ____.
False
Niacin's lipid-lowering effects were discovered in the year ____.
False
Excessive intake of niacin can cause severe skin flushing combined with ________.
False
The recommended tolerable upper intake level of niacin is ___ mg per day.
False
Niacin can be used for the prevention of premenstrual ________.
False
For individuals 19 years of age and older, the recommended amount of niacin for males is ___ mg NE.
False
The uses of niacin include protection from toxins and pollutants, improvement in ________, and relaxation promotion.
False
Niacin intake was found to have a U-shaped relationship with depression in adults.
True
Moderate niacin intake did not reduce depression risk according to the study.
False
The lowest risk of depression was observed at a niacin intake of approximately 36 mg/day.
True
Niacin may lower the risk of Alzheimer's disease and offer protection against cognitive decline.
True
Niacin interacts with the niacin receptor HCAR2, primarily expressed by neurons in the brain.
False
An FDA-approved niacin formulation (Niaspan®) was administered daily in the study on Alzheimer's disease.
True
The study on Alzheimer's disease showed a significant increase in Aβ burden and plaques after administering niacin.
False
People with Parkinson’s disease were found to have higher vitamin B3 levels according to the study at Augusta University.
False
Low-dose niacin improved motor scores and secondary measures in people with Parkinson’s disease.
True
Niacin has no potential to enhance treatment for Parkinson's disease.
False
Niacin is also known as nicotinic acid. True or False?
True
Niacin is a vitamer of vitamin B2. True or False?
False
Niacin is essential for human health. True or False?
True
Niacin's role in the cure of pellagra was discovered in the late 1930s. True or False?
True
Excessive intake of niacin can cause abdominal pain and gout. True or False?
True
Niacin can be used for the prevention of premenstrual headaches. True or False?
True
The recommended amount of niacin for males 19 years of age and older is 16 mg NE. True or False?
True
Excessive intake of niacin can reduce glucose tolerance and insulin resistance. True or False?
True
Niacin is produced by plants and animals from the amino acid tyrosine. True or False?
False
The tolerable upper intake level of niacin is 35 mg per day. True or False?
True
Niacin intake showed a U-shaped relationship with depression in adults according to the study?
True
The study on Alzheimer's disease showed that niacin may increase the risk of Aβ burden and plaques?
False
Niacin plays no potential role in enhancing treatment for Parkinson's disease?
False
Vitamin B3 deficiency may contribute to Parkinson’s disease symptoms like fatigue, sleep dysfunction, and mood changes?
True
Niacin interacts with the niacin receptor primarily expressed by neurons in the brain?
False
Niacin is also known as nicotinic acid?
True
The lowest risk of depression was observed at a niacin intake of approximately 36 mg/day?
True
An FDA-approved niacin formulation (Niaspan®) was not administered daily in the study on Alzheimer's disease?
False
People with Parkinson’s disease were found to have lower vitamin B3 levels according to the study at Augusta University?
True
Excessive intake of niacin can cause severe skin flushing combined with itching?
True
Study Notes
Niacin Overview
- Niacin is also known as nicotinic acid.
- Niacin is a vitamer of vitamin B3.
- Niacin is produced by plants and animals from the amino acid tryptophan.
Health Effects
- Niacin's role in the cure of pellagra was discovered in the 1930s.
- Niacin's lipid-lowering effects were discovered in the year 1950.
- Excessive intake of niacin can cause severe skin flushing combined with itching.
- The recommended tolerable upper intake level of niacin is 35 mg per day.
Benefits and Uses
- Niacin can be used for the prevention of premenstrual headaches.
- For individuals 19 years of age and older, the recommended amount of niacin for males is 14 mg NE.
- The uses of niacin include protection from toxins and pollutants, improvement in cholesterol levels, and relaxation promotion.
Relationship with Depression and Alzheimer's Disease
- Niacin intake was found to have a U-shaped relationship with depression in adults.
- The lowest risk of depression was observed at a niacin intake of approximately 36 mg/day.
- Niacin may lower the risk of Alzheimer's disease and offer protection against cognitive decline.
- An FDA-approved niacin formulation (Niaspan®) was administered daily in the study on Alzheimer's disease.
Relationship with Parkinson's Disease
- People with Parkinson’s disease were found to have higher vitamin B3 levels according to the study at Augusta University.
- Low-dose niacin improved motor scores and secondary measures in people with Parkinson’s disease.
- Niacin has no potential to enhance treatment for Parkinson's disease.
Test your knowledge of the history, importance, and role of niacin, also known as vitamin B3, in human health. Learn about its discovery by chemist Hugo Weidel, its role in curing pellagra, and its fortification in flour.
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